NURS 3365 UPDATED 2026 EXAM SCRIPT QUESTIONS
AND ANSWERS RATED A+
✔✔steady state - ✔✔the equilibrium when the amount of drug entering equals the same
amount exiting
✔✔clearance - ✔✔how fast the drug leaves the body
✔✔half life t1/2 - ✔✔time it takes for 50% of a drug to be eliminated from the body
✔✔bio transformation - ✔✔changing of a parent drug to metabolite , outcome of
motabolism
✔✔prodrug - ✔✔drug that becomes active only after metabolism to its active metabolite
✔✔p-glycoprotien - ✔✔pumps drugs back into the circulation to protect the brain and
placenta
✔✔first pass effect - ✔✔gut circulation through the portal vein to the liver
✔✔what require a higher dose IV or oral - ✔✔oral
✔✔CYP450 inducers - ✔✔nicotine. makes more cyp450 enzymes
✔✔CYP450 inhibitors - ✔✔grapefruit or tagament. make less CYP450 risk of intoxicity
✔✔main excretion organ - ✔✔kidney/ renal
✔✔creatine serum range - ✔✔0.8-1.4
✔✔BP normal range - ✔✔100-120
✔✔HR normal range - ✔✔60-100
✔✔glucose level normal - ✔✔60-100
✔✔respiration normal level - ✔✔12-20
✔✔albumin - ✔✔> 3.0
✔✔normal potassium level - ✔✔3.5-5
✔✔normal weight - ✔✔2.2lb=1Kg=1L
, ✔✔drug action - ✔✔MOA of a drug
✔✔Drug effect - ✔✔outcome of a drug
✔✔Efficacy - ✔✔Measure of the maximum response a drug can produce
✔✔additive - ✔✔same mechanism of action 1+1=2
✔✔synergistic - ✔✔Different mechanism of action 1+1=3
✔✔therapeutic index - ✔✔the margine between the effective dose and the lethal dose
✔✔heptatoxicity - ✔✔DILT= drug induced liver toxicity. MOST common
✔✔types of drug toxicity - ✔✔Cardio toxicity, neurotoxicity, ototoxicity, nephrotoxicity,
hepatotoxicity
✔✔example of hepatoxicity - ✔✔TYLENOL produces a toxic metabolite that can cause
liver failure and need for a liver transplant
✔✔dosage calculations for pediatrics - ✔✔mg/kg body weight
✔✔fetal drug explosure via placenta - ✔✔drug properties
fetal gastral age
maternal factors
✔✔as creatine increases ex 2.5 - ✔✔clearance decreases and increases toxicity
✔✔why is medical reconciliation important - ✔✔so PT wont have a drug interaction
✔✔LASA drugs - ✔✔those that look alike and sound alike
✔✔high alert drugs - ✔✔those with a narrow therapuetic index
✔✔6 rights of administration - ✔✔PT
time
dose
route
drug
documents
✔✔what are some methods of preventing medication error - ✔✔dont abbreviate
dont know, ask
AND ANSWERS RATED A+
✔✔steady state - ✔✔the equilibrium when the amount of drug entering equals the same
amount exiting
✔✔clearance - ✔✔how fast the drug leaves the body
✔✔half life t1/2 - ✔✔time it takes for 50% of a drug to be eliminated from the body
✔✔bio transformation - ✔✔changing of a parent drug to metabolite , outcome of
motabolism
✔✔prodrug - ✔✔drug that becomes active only after metabolism to its active metabolite
✔✔p-glycoprotien - ✔✔pumps drugs back into the circulation to protect the brain and
placenta
✔✔first pass effect - ✔✔gut circulation through the portal vein to the liver
✔✔what require a higher dose IV or oral - ✔✔oral
✔✔CYP450 inducers - ✔✔nicotine. makes more cyp450 enzymes
✔✔CYP450 inhibitors - ✔✔grapefruit or tagament. make less CYP450 risk of intoxicity
✔✔main excretion organ - ✔✔kidney/ renal
✔✔creatine serum range - ✔✔0.8-1.4
✔✔BP normal range - ✔✔100-120
✔✔HR normal range - ✔✔60-100
✔✔glucose level normal - ✔✔60-100
✔✔respiration normal level - ✔✔12-20
✔✔albumin - ✔✔> 3.0
✔✔normal potassium level - ✔✔3.5-5
✔✔normal weight - ✔✔2.2lb=1Kg=1L
, ✔✔drug action - ✔✔MOA of a drug
✔✔Drug effect - ✔✔outcome of a drug
✔✔Efficacy - ✔✔Measure of the maximum response a drug can produce
✔✔additive - ✔✔same mechanism of action 1+1=2
✔✔synergistic - ✔✔Different mechanism of action 1+1=3
✔✔therapeutic index - ✔✔the margine between the effective dose and the lethal dose
✔✔heptatoxicity - ✔✔DILT= drug induced liver toxicity. MOST common
✔✔types of drug toxicity - ✔✔Cardio toxicity, neurotoxicity, ototoxicity, nephrotoxicity,
hepatotoxicity
✔✔example of hepatoxicity - ✔✔TYLENOL produces a toxic metabolite that can cause
liver failure and need for a liver transplant
✔✔dosage calculations for pediatrics - ✔✔mg/kg body weight
✔✔fetal drug explosure via placenta - ✔✔drug properties
fetal gastral age
maternal factors
✔✔as creatine increases ex 2.5 - ✔✔clearance decreases and increases toxicity
✔✔why is medical reconciliation important - ✔✔so PT wont have a drug interaction
✔✔LASA drugs - ✔✔those that look alike and sound alike
✔✔high alert drugs - ✔✔those with a narrow therapuetic index
✔✔6 rights of administration - ✔✔PT
time
dose
route
drug
documents
✔✔what are some methods of preventing medication error - ✔✔dont abbreviate
dont know, ask
