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Summary Grade 12 IEB Life Sciences – Endocrine System Handwritten Notes

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These handwritten notes provide a detailed and easy-to-understand summary of the Endocrine System for Grade 12 IEB Life Sciences, fully aligned with the IEB syllabus. Concepts are explained in a student-friendly format, making it simple to revise and apply in exams.

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Endocrine System
Homeostasis : maintaining
2 constant internal environment


Endo : "ductless" >
-
into bloodstream



& me




Zer
Exo



Saliva
A
- ↑ Nears
swea



Hormones are
specific to
target organs
Hormones either stimulate or inhibit







Hypothyroidism ema
children

Hyper ,
cretinism

-
Thyroidism iodine
deficiency
nervousness Corticotropin H
I -
1 rel . .




weight
-




. Growth
2 H . rel . H.




-
isease rel H
.
3 Ganadotropin .




rel H
4.
Thyrotropin
.




Dopamine
.
5




Thyroxin
1 .

TSH
I .
>
-
ADH ↓ waterme
Decreases
water volume
Diuresis-high

largevole

water

volume
see



a




Adrenocorticotropic -> Diabetes insipidus (disorder)
Cortisol,pressure
lo
.
2

Growth - Hormone JACTH)
.
2
Oxytosin



3 .


GH
4
. Prolactin >
-
milk production
CH + FSH uterine contractions
.
5
Gonadotropins -




milk ejection

, metabolism
↳ all the chemical reactions inside the
body
Feedback
Negative
eg
. Thyroid

Thyrotropin
-

Releasing HIGH LEVELS OF T4/T3
Chypothalamus
Hormone
of TRH
suppressproduction I
and TSH (Pituitary) - reduces T4/Tz hormones
Thyroid LOW LEVELS OF T4/T3
stimulating
Hormone Increase production of TRH
I
Chypothalamus
and TSH (Pituitary) -> increases T4/Tz hormones

Calcitonin
↓ blood Calcium


-




Thyroxine Triiodothyronine
90 % 10 %




NORMAL BLOOD SUGAR

4-8 mmol/L floor
Homeostasis 14 is the



HIGH LEVELS OF BLOOD GIUCOSE
-
Hyperglycemia=
~
> necrosis , Kidney failure , glaucoma
LOW LEVELS OF BLOOD GIUCOSE
-
Hypoglycemia + cells die ,
brain cant use
fats/protein
for
Less energy energy

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