Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
Integrated Fast-Revision MCQs
Harrison’s Principles of Internal Medicine, 22nd ed.
1. The Practice of Medicine
Which principle best defines evidence-based clinical practice?
A. Reliance on expert opinion
B. Application of population averages to all patients
C. Integration of best evidence, clinical expertise, and patient
values
D. Use of randomized trials only
Correct Answer: C
Rationale: Harrison defines evidence-based medicine as
integrating scientific evidence with clinician judgment and
patient preferences.
Citation: Harrison’s, 22nd ed., The Practice of Medicine
,2. The Practice of Medicine
Which factor most strongly influences variability in clinical
outcomes?
A. Availability of technology
B. Clinician decision-making
C. Patient genetics alone
D. Hospital size
Correct Answer: B
Rationale: Harrison emphasizes that clinician judgment and
decisions significantly affect diagnostic accuracy and outcomes.
Citation: Harrison’s, 22nd ed., The Practice of Medicine
3. Promoting Good Health
Which intervention provides the greatest population-level
health benefit?
A. Advanced imaging
B. Lifestyle risk reduction
C. Specialty referral
D. Genomic testing
Correct Answer: B
Rationale: Health promotion and lifestyle modification reduce
morbidity and mortality more effectively than downstream
interventions.
Citation: Harrison’s, 22nd ed., Promoting Good Health
, 4. Promoting Good Health
Which nursing action best supports primary prevention?
A. Early disease detection
B. Symptom management
C. Risk factor modification education
D. Rehabilitation planning
Correct Answer: C
Rationale: Primary prevention targets risk factors before
disease onset.
Citation: Harrison’s, 22nd ed., Promoting Good Health
5. Vaccine Opposition and Hesitancy
Which factor most commonly contributes to vaccine
hesitancy?
A. Cost barriers
B. Religious doctrine
C. Misinformation and mistrust
D. Lack of efficacy
Correct Answer: C
Rationale: Harrison identifies misinformation and mistrust as
central drivers of vaccine opposition.
Citation: Harrison’s, 22nd ed., Vaccine Opposition and Hesitancy
6. Vaccine Opposition and Hesitancy
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
Integrated Fast-Revision MCQs
Harrison’s Principles of Internal Medicine, 22nd ed.
1. The Practice of Medicine
Which principle best defines evidence-based clinical practice?
A. Reliance on expert opinion
B. Application of population averages to all patients
C. Integration of best evidence, clinical expertise, and patient
values
D. Use of randomized trials only
Correct Answer: C
Rationale: Harrison defines evidence-based medicine as
integrating scientific evidence with clinician judgment and
patient preferences.
Citation: Harrison’s, 22nd ed., The Practice of Medicine
,2. The Practice of Medicine
Which factor most strongly influences variability in clinical
outcomes?
A. Availability of technology
B. Clinician decision-making
C. Patient genetics alone
D. Hospital size
Correct Answer: B
Rationale: Harrison emphasizes that clinician judgment and
decisions significantly affect diagnostic accuracy and outcomes.
Citation: Harrison’s, 22nd ed., The Practice of Medicine
3. Promoting Good Health
Which intervention provides the greatest population-level
health benefit?
A. Advanced imaging
B. Lifestyle risk reduction
C. Specialty referral
D. Genomic testing
Correct Answer: B
Rationale: Health promotion and lifestyle modification reduce
morbidity and mortality more effectively than downstream
interventions.
Citation: Harrison’s, 22nd ed., Promoting Good Health
, 4. Promoting Good Health
Which nursing action best supports primary prevention?
A. Early disease detection
B. Symptom management
C. Risk factor modification education
D. Rehabilitation planning
Correct Answer: C
Rationale: Primary prevention targets risk factors before
disease onset.
Citation: Harrison’s, 22nd ed., Promoting Good Health
5. Vaccine Opposition and Hesitancy
Which factor most commonly contributes to vaccine
hesitancy?
A. Cost barriers
B. Religious doctrine
C. Misinformation and mistrust
D. Lack of efficacy
Correct Answer: C
Rationale: Harrison identifies misinformation and mistrust as
central drivers of vaccine opposition.
Citation: Harrison’s, 22nd ed., Vaccine Opposition and Hesitancy
6. Vaccine Opposition and Hesitancy
