NR546 PSYCHOPHARM MIDTERM COMPLETE FINAL
EXAM STUDY GUIDE WITH PRACTICE QUESTIONS AND
VERIFIED ANSWERS 2025–2026
How does the orbitofrontal cortex (OFC) affect the amygdala? - correct answer -inhibits and
activates the amygdala
Wernicke's area is associated with which of the following? - correct answer -speech
comprehension
The limbic system is associated with which of the following - correct answer -emotion and
learning
Which brain structure is most associated with long term memory? - correct answer -
hippocampus
When prescribing psychotropic medications, the PMHNP knows that these medications work
within which specific areas? - correct answer -mood
Which of the following are involved in regulating neurotransmission via excitation-secretion
coupling? - correct answer -voltage-sensitive sodium channels and voltage-sensitive calcium
channels
What system influences the length of time for a drug to achieve efficacy? - correct answer -
signal transduction cascades
One of the signal transduction cascades, pass the message from a first receptor to a second
messenger. - correct answer -G protein linked systems
,Human central nervous system communication at synapses is which of the following? - correct
answer -chemical
Which of the following is an excitatory neurotransmitter? - correct answer -glutamate
Which statement correctly pairs the pharmacodynamic effect with its definition? - correct
answer -antagonist effect - drug binds to receptor, but does not activate a response
A major current hypothesis for the cause of schizophrenia proposes that N-methyl-d-aspartate
(NMDA) receptors may be which of the following?
Correct! - correct answer -hypofunctional
Which medication is least associated with weight gain? - correct answer -aripiprazole
Which dopamine pathway is associated with positive symptoms of schizophrenia? - correct
answer -mesolimbic pathway
Which pathway is associated with negative symptoms? - correct answer -The mesocortical
pathway
Is part of the extrapyramidal nervous system and associated with extrapyramidal symptoms
(EPS) - correct answer -nigrostriatal pathway
This pathway is associated with hyperprolactinemia. - correct answer -The tuberoinfundibular
pathway
A 34-year old male recently began experiencing breast secretions while receiving risperidone .
Which dopamine pathway is associated with this side effect? - correct answer -
tuberoinfundibular pathway
, A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of
schizophrenia. Regarding affinity, atypical antipsychotics demonstrate which of the following
most often? - correct answer -Atypical antipsychotics have equal positive symptom
antipsychotic actions and low extrapyramidal symptoms.
is a syndrome that can be associated with several different psychiatric disorders. Symptoms
include hallucinations, delusions, disorganized speech, disorganized behavior, and distortions of
reality. This syndrome can affect a person's cognition, affective response, communication,
capacity to recognize reality, and ability to relate to others. - correct answer -psychosis
What Diagnosis require the presence of psychosis? - correct answer -schizophrenia
substance-induced psychotic disorders
schizophreniform disorder
schizoaffecive disorder
delusional disorder
brief psychotic disorder
psychotic disorder due to a medical condition
What diagnosis has a diagnosis of psychosis as a feature? - correct answer -mania
depression
cognitive disorders
dementia
What are some positive symptoms? - correct answer -Hallucinations
Delusions
Thought disorder
Hostility
EXAM STUDY GUIDE WITH PRACTICE QUESTIONS AND
VERIFIED ANSWERS 2025–2026
How does the orbitofrontal cortex (OFC) affect the amygdala? - correct answer -inhibits and
activates the amygdala
Wernicke's area is associated with which of the following? - correct answer -speech
comprehension
The limbic system is associated with which of the following - correct answer -emotion and
learning
Which brain structure is most associated with long term memory? - correct answer -
hippocampus
When prescribing psychotropic medications, the PMHNP knows that these medications work
within which specific areas? - correct answer -mood
Which of the following are involved in regulating neurotransmission via excitation-secretion
coupling? - correct answer -voltage-sensitive sodium channels and voltage-sensitive calcium
channels
What system influences the length of time for a drug to achieve efficacy? - correct answer -
signal transduction cascades
One of the signal transduction cascades, pass the message from a first receptor to a second
messenger. - correct answer -G protein linked systems
,Human central nervous system communication at synapses is which of the following? - correct
answer -chemical
Which of the following is an excitatory neurotransmitter? - correct answer -glutamate
Which statement correctly pairs the pharmacodynamic effect with its definition? - correct
answer -antagonist effect - drug binds to receptor, but does not activate a response
A major current hypothesis for the cause of schizophrenia proposes that N-methyl-d-aspartate
(NMDA) receptors may be which of the following?
Correct! - correct answer -hypofunctional
Which medication is least associated with weight gain? - correct answer -aripiprazole
Which dopamine pathway is associated with positive symptoms of schizophrenia? - correct
answer -mesolimbic pathway
Which pathway is associated with negative symptoms? - correct answer -The mesocortical
pathway
Is part of the extrapyramidal nervous system and associated with extrapyramidal symptoms
(EPS) - correct answer -nigrostriatal pathway
This pathway is associated with hyperprolactinemia. - correct answer -The tuberoinfundibular
pathway
A 34-year old male recently began experiencing breast secretions while receiving risperidone .
Which dopamine pathway is associated with this side effect? - correct answer -
tuberoinfundibular pathway
, A 44-year-old woman is initiated on an atypical antipsychotic for the treatment of
schizophrenia. Regarding affinity, atypical antipsychotics demonstrate which of the following
most often? - correct answer -Atypical antipsychotics have equal positive symptom
antipsychotic actions and low extrapyramidal symptoms.
is a syndrome that can be associated with several different psychiatric disorders. Symptoms
include hallucinations, delusions, disorganized speech, disorganized behavior, and distortions of
reality. This syndrome can affect a person's cognition, affective response, communication,
capacity to recognize reality, and ability to relate to others. - correct answer -psychosis
What Diagnosis require the presence of psychosis? - correct answer -schizophrenia
substance-induced psychotic disorders
schizophreniform disorder
schizoaffecive disorder
delusional disorder
brief psychotic disorder
psychotic disorder due to a medical condition
What diagnosis has a diagnosis of psychosis as a feature? - correct answer -mania
depression
cognitive disorders
dementia
What are some positive symptoms? - correct answer -Hallucinations
Delusions
Thought disorder
Hostility
