Questions and Answers | A+ Score
Assured
What is a vaccine given as an immune stimulant after surgery for non-
muscle invasive bladder cancer to prevent progression to muscle invasive?
- 🧠ANSWER ✔✔BCG
What are immunotherapy drugs also known as? - 🧠ANSWER ✔✔Immune
checkpoint inhibitors
How do immune checkpoint inhibitors work? - 🧠ANSWER ✔✔Block the
regulatory "off switch" on T cells that prevent them from attacking cancer
cells
, This allows the immune system to mount an appropriate response to
cancer cells
What are 3 examples of targets of immune checkpoint inhibitors? -
🧠ANSWER ✔✔CLTA4
PD1
PDL1
What is CTLA4? - 🧠ANSWER ✔✔Cytotoxic T lymphocyte antigen 4
Where is CTLA4 expressed? - 🧠ANSWER ✔✔T lymphocytes
What is PD1? - 🧠ANSWER ✔✔Programmed cell death protein 1
What is PDL1? - 🧠ANSWER ✔✔Programmed death ligand 1
How do most licensed immune checkpoint inhibitors work? - 🧠ANSWER
✔✔Long acting monoclonal antibodies that cause immune checkpoint
blockage to release anti-tumour immunity
How is immunotherapy delivered? - 🧠ANSWER ✔✔IV
How is immunotherapy dosed? - 🧠ANSWER ✔✔According to body weight