CLINICAL MANIFESTATIONS OF
GASTROENTERITIS AND POSSIBLE RENAL
INJURY ACADEMIC PREP SCRIPT 2026 TESTED
KNOWLEDGE VERIFIED ANSWERS
◉ Acute Poststreptococcal Glomerulonephritis most commonly
effects. Answer: children and young adults
◉ Acute Poststreptococcal Glomerulonephritis patho. Answer: 5-21
days post infection of pharynx or skin (strep, impetigo) by
nephrotoxic strains of group-B hemolytic streptococci →
inflammation of glomeruli
**if strep not tx causes this, this is why we rly care abt treating
strep!!!
**95% recover completely
◉ Acute Poststreptococcal Glomerulonephritis s/s:. Answer:
•Generalized body edema (result of ↓ glomerular filtration)
•Hypertension (from ↑extracellular vol.)
•Oliguria
•Smoky urine - indicative of bleeding in upper urinary tract
, •Proteinuria
◉ Acute Poststreptococcal Glomerulonephritis Management.
Answer: **PRVENTION IS KEY!!**
KEY: MANAGE FLUID OVERLOAD + TX UNDERLYING INFECTION
- fluid/Na restriction
- diuretics
- if BUN increased too much then restrict protein
- ANTIBX if infection still present
◉ What is Nephrotic Syndrome?. Answer: not one specific disease,
but a collection of symptoms that occur when the glomerular
membrane becomes excessively permeable to proteins.
It's a clinical course that can result from many underlying kidney or
systemic diseases, such as:
Diabetes (diabetic nephropathy)
Lupus (systemic lupus erythematosus)
◉ Nephrotic Syndrome - Pathophysiology. Answer: damage to
glomerular membrane → increased permeability → MASSIVE
PROTEIN LOSS → PROTEINURIA, HYPOALBUMINEMIA → DEC
ONCOTIC PRESSURE → EDEMA/ASCITES/PLEURAL EFFUSION →
liver compensates by making more lipoproteins → DYSLIPIDEMIA ↑
cholesterol/LDLs → loss of immunoglobulins → increased
GASTROENTERITIS AND POSSIBLE RENAL
INJURY ACADEMIC PREP SCRIPT 2026 TESTED
KNOWLEDGE VERIFIED ANSWERS
◉ Acute Poststreptococcal Glomerulonephritis most commonly
effects. Answer: children and young adults
◉ Acute Poststreptococcal Glomerulonephritis patho. Answer: 5-21
days post infection of pharynx or skin (strep, impetigo) by
nephrotoxic strains of group-B hemolytic streptococci →
inflammation of glomeruli
**if strep not tx causes this, this is why we rly care abt treating
strep!!!
**95% recover completely
◉ Acute Poststreptococcal Glomerulonephritis s/s:. Answer:
•Generalized body edema (result of ↓ glomerular filtration)
•Hypertension (from ↑extracellular vol.)
•Oliguria
•Smoky urine - indicative of bleeding in upper urinary tract
, •Proteinuria
◉ Acute Poststreptococcal Glomerulonephritis Management.
Answer: **PRVENTION IS KEY!!**
KEY: MANAGE FLUID OVERLOAD + TX UNDERLYING INFECTION
- fluid/Na restriction
- diuretics
- if BUN increased too much then restrict protein
- ANTIBX if infection still present
◉ What is Nephrotic Syndrome?. Answer: not one specific disease,
but a collection of symptoms that occur when the glomerular
membrane becomes excessively permeable to proteins.
It's a clinical course that can result from many underlying kidney or
systemic diseases, such as:
Diabetes (diabetic nephropathy)
Lupus (systemic lupus erythematosus)
◉ Nephrotic Syndrome - Pathophysiology. Answer: damage to
glomerular membrane → increased permeability → MASSIVE
PROTEIN LOSS → PROTEINURIA, HYPOALBUMINEMIA → DEC
ONCOTIC PRESSURE → EDEMA/ASCITES/PLEURAL EFFUSION →
liver compensates by making more lipoproteins → DYSLIPIDEMIA ↑
cholesterol/LDLs → loss of immunoglobulins → increased
