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Summary Cardiac Pharmacology Simplified – NURS 231 Pharmacology for Nursing (ACE Inhibitors, Beta Blockers & Diuretics) | Based on Katzung 16e

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This document is a clear, exam-focused summary of cardiac pharmacology designed for USA nursing and health science students. The notes are based on Katzung: Basic & Clinical Pharmacology, 16th Edition and focus on the most tested cardiovascular drug classes, including: ACE inhibitors Beta-adrenoceptor blockers Diuretics (loop, thiazide, potassium-sparing) Each drug class includes: Mechanism of action (Katzung-aligned) Therapeutic uses Contraindications Adverse effects Nursing considerations High-yield memory tips for exams Ideal for: Nursing pharmacology exams Med-Surg preparation NCLEX-style revision Last-minute study and quick recall

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CARDIAC PHARMACOLOGY SIMPLIFIED
ACE Inhibitors • Beta Blockers • Diuretics

Course: Pharmacology (Cardiovascular System)
Primary Reference: Katzung – Basic & Clinical Pharmacology, 16th Edition
Study Program: Nursing / Medicine / Clinical Health Sciences
Document Type: Course Summary & Exam Revision Notes
Level: Undergraduate (Year 2–3)

What This Summary Includes :
 Katzung-aligned mechanisms
 Clinical uses & pharmacodynamics
 Adverse effects & contraindications
 Nursing & exam-focused points
 High-yield memory tips




1

, 1. ANGIOTENSIN CONVERTING ENZYME (ACE )
INHIBITORS
(Katzung BCP 16e – Renin–Angiotensin–Aldosterone System)

Common Drugs (-pril)
Captopril
Enalapril
Lisinopril
Ramipril

Mechanism of Action
Inhibit angiotensin-converting enzyme (ACE)
↓ Conversion of Angiotensin I → Angiotensin II
↓ Vasoconstriction
↓ Aldosterone secretion
↓ Sodium and water retention
↑ Bradykinin levels → vasodilation

Pharmacologic Effects
↓ Peripheral vascular resistance (afterload)
↓ Blood pressure
↓ Cardiac remodeling in heart failure
Reno protective effects in diabetes

Therapeutic Uses
Hypertension
Chronic heart failure
Post–myocardial infarction
Diabetic nephropathy

Adverse Effects
Dry cough (Bradykinin-mediated)
Hypotension (first-dose effect)
Hyperkalemia
Acute renal failure (renal artery stenosis)
Angioedema (rare but fatal)

Contraindications
Pregnancy (teratogenic)
Bilateral renal artery stenosis
History of angioedema

Nursing & Exam Notes
Monitor blood pressure, renal function, and serum potassium
Warn patient about cough
Stop drug immediately if angioedema occurs

Memory Tip:
“ACE → Cough, K⁺ ↑, BP ↓”



2

Connected book
 image
Bertram G. Katzung Basic and Clinical Pharmacology
Edition: 2001 ISBN: 9780071179683 Edition: Unknown

Document information

Summarized whole book?
No
Which chapters are summarized?
Chapter 11, 12, 15
Uploaded on
January 18, 2026
Number of pages
7
Written in
2025/2026
Type
Summary
$10.99

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