CHAPTER 4 CLINICAL IMMUNOLOGY
AND SEROLOGY QUESTIONS AND
CORRECT ANSWERS 2026
CHEMOKINES - ANS -LARGE FAMILY OF CYTOKINES THAT THE ABILITY TO RECRUIT
SPECIFIC CELLS TO A PARTICULAR SITE.
THYMOCYTES - ANS -PRECURSORS THAT BECOME T CELLS
MACROPHAGES, DENDRITIC CELLS AND FRIBOBLAST - ANS -HELP DEVELOP T CELLS
double negative thymocytes - ANS -Immature T cells in the thymus that lack
expression of the two co-receptors CD4 and CD8.
, T - CELL MATURATION - ANS -IN THE THYMUS, T-LYMPHOCYTES PRECURSORS
ENTER THE THYMUS AND MIGRATE UPWARD IN THE CORTEX AND BEGIN THE
DEVELOPMENT OF T CELL RECEPTOR. FEW BECOME GAMMA DELTA CHAINS BUT
THE MAJORITY ARE ALPHA BETA CHAINS NOW CONTAINING CD4 AND CD8 WHICH
ARE DOUBLE POSITIVE , THIS CELL NOW CONTAINS VARIABLE REGIONS THAT
REGONIZE SPECIFIC ANTIGENS
DOUBLE POSITIVE - ANS -SELECTION TAKES PLACE IN CD3 T CELL ONCE IT BECOME
DOUBLE POSITIVE IT IS BEING SELECTIVE OF BECOMING SINGLE POSITIVE WHICH
ONLY CONTAINS EITHER CD4 OR CD8 . IF NOT SELECTED THATS IS WHEN
MACROPHAGES AND DENDRITIC CELLS TAKE THEM OUT BECAUSE THE IMMATURE
T CELL IS RESPONSING TO SELF - ANTIGEN
MUST BE AN INTERMEDIATE BINDING - DPCD4/CD8 ---> SP CD4 AND SP CD8
2ND STAGE MUST BE NO BINDING SP EXITS SP CD4+ OR SP CD8+
AND SEROLOGY QUESTIONS AND
CORRECT ANSWERS 2026
CHEMOKINES - ANS -LARGE FAMILY OF CYTOKINES THAT THE ABILITY TO RECRUIT
SPECIFIC CELLS TO A PARTICULAR SITE.
THYMOCYTES - ANS -PRECURSORS THAT BECOME T CELLS
MACROPHAGES, DENDRITIC CELLS AND FRIBOBLAST - ANS -HELP DEVELOP T CELLS
double negative thymocytes - ANS -Immature T cells in the thymus that lack
expression of the two co-receptors CD4 and CD8.
, T - CELL MATURATION - ANS -IN THE THYMUS, T-LYMPHOCYTES PRECURSORS
ENTER THE THYMUS AND MIGRATE UPWARD IN THE CORTEX AND BEGIN THE
DEVELOPMENT OF T CELL RECEPTOR. FEW BECOME GAMMA DELTA CHAINS BUT
THE MAJORITY ARE ALPHA BETA CHAINS NOW CONTAINING CD4 AND CD8 WHICH
ARE DOUBLE POSITIVE , THIS CELL NOW CONTAINS VARIABLE REGIONS THAT
REGONIZE SPECIFIC ANTIGENS
DOUBLE POSITIVE - ANS -SELECTION TAKES PLACE IN CD3 T CELL ONCE IT BECOME
DOUBLE POSITIVE IT IS BEING SELECTIVE OF BECOMING SINGLE POSITIVE WHICH
ONLY CONTAINS EITHER CD4 OR CD8 . IF NOT SELECTED THATS IS WHEN
MACROPHAGES AND DENDRITIC CELLS TAKE THEM OUT BECAUSE THE IMMATURE
T CELL IS RESPONSING TO SELF - ANTIGEN
MUST BE AN INTERMEDIATE BINDING - DPCD4/CD8 ---> SP CD4 AND SP CD8
2ND STAGE MUST BE NO BINDING SP EXITS SP CD4+ OR SP CD8+
