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HESI A2 Biology Exam Study Guide – Practice Questions, Answers & Key Concepts

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This study guide is designed to help students successfully prepare for the HESI A2 Biology Exam. It covers all major biology topics tested on the exam, including cell structure and function, biomolecules, enzymes, metabolism, photosynthesis, cellular respiration, DNA and RNA, genetics, mitosis and meiosis, evolution, and ecology. The material includes clear explanations, exam-style practice questions, and concise summaries to strengthen understanding and improve test performance. Ideal for nursing and allied health program applicants preparing for the HESI Admission Assessment (A2)

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Uploaded on
January 15, 2026
Number of pages
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Written in
2025/2026
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HESI A2 Biology Exam Questions and Answers 2024/2025
Study online at https://quizlet.com/_haib5s
1. Passive transport: Nutrients exchange occurs without the need for cellular energy.
2. Exocytosis: Process used by the cell to secrete material outside the plasma membrane.
3. Homeostasis: Process by which organisms maintain a relatively stable internal environment.
4. Qualities measures: Water can have a cold temperature.
5. Elephantine: Family gene the elephant goes in.
6. Antibiotics: Treat bacteria.
7. Liver damage effect: It would affect urine.
8. Connective tissue: The most abundant tissue in the body.
9. Phagocytosis: Uptake of food through the cellular membrane creating a food vacuole.
10. Broad needles: Dominant trait over the thin needle trait in pine trees.
11. Isotonic solution: Must be injected into tissues to prevent cells from shrinking or swelling.
12. Carbohydrates: Macromolecule that provides immediate energy for metabolism.
13. Enzyme action: Lowers the activation energy to increase the rate of a biological reaction.
14. Surface to volume ratio: Cells require a large ratio for nutrient and gas exchange.
15. Epithelial tissue: Covers the outside of the body.
16. Prokaryotic: Cell means before nucleus.
17. Lipids: Macromolecule that provides a lot of energy besides carbohydrates.
18. Immune system: Involves immediate as well as slower response specifically to infecting agents.
19. Prokaryotic cell: A cell that does not contain membrane bound organelles or a defined nucleus.
20. Eukaryotic cell: A cell that contains a nucleus and membrane-bound organelles.
21. Metabolism: Sum of all chemical reactions in an organism.
22. Photosynthesis end product: Oxygen.
23. Telophase: Cytokinesis pinches into two cells to split into two cells following this phase.
24. Dominant allele: Represented by a capitalized letter in a Punnet square.
25. Transcription: DNA for protein synthesis.
26. Chloroplasts: Where photosynthesis occurs.
27. Hypertonic: Term for when a cell shrinks (lower concentration).
28. Uracil: Not a nitrogenous base found in DNA.
29. Osmosis: Diffusion of water through a permeable membrane.
30. Cytosine: In DNA, binds with guanine.
31. Muscular tissue: Allows movement in the body.
32. Meiosis: Process by which gametes are produced.
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