MSN 611 Final Exam Questions and Verified
Answers
Location of H4 receptors Correct Answer: eosinophils, neutrophils and T cells
second-generation antihistamine that cannot be removed by hemodialysis Correct
Answer: cetirizine (hydrochloride) aka Zyrtec
diagnosis of enterobiasis Correct Answer: caused by small threadlike pinworm,
Enterobius vermicularis, perianal cutaneous irritation, may result in dermatitis and
secondary bacterial infections. DIAGNOSIS: perianal swab using adhesive tape,
examined for eggs
treatment modalities of tuberculosis Correct Answer: directly observed therapy,
adherence to drug regimen, important for anything less than daily doses, highly
susceptible to drug-drug interactions
according to universal prescribing alerts for ahminoglycosides, extended use
increases risk for infection by which pathogens Correct Answer: C.difficile-
associated diarrhea and pseudomembranous colitis with extended use
mode of administration of dactinomycin Correct Answer: vesicants, should be
administered only by intravenous route to prevent extravasation. If extravasation
occurs administration should be stopped, monitor for signs of infection & bleeding.
Myelosuppression
FDA- approved indication for methotrexate Correct Answer: meningeal leukemia,
trophoblastic neoplasms. Breast Cancer
Synthetic muscarinic receptor antagonist that possesses M3 receptor selectivity
Correct Answer: darifenacin & solifenacin
Autonomic agents associated simulation of insulin production, increase
glycogenolysis in the liver and complicate the management of diabetes mellitus
, Correct Answer: may stimulate insulin production- increase glycogenolysis in the
liver and complicate the management--sympathomimetic autonomic agents
most commonly used therapy for iron-deficiency anemia Correct Answer: ferrous
sulfate
fatalities have occurred with the test dose of which drug Correct Answer: iron
dextran
antilipemic agent that targets triglycerides Correct Answer: Fibrates
mechanism of action calcium-channel blocking agents Correct Answer: act on
calcium channels in large vessels to produce vasodilation and subsequent reduction
in blood pressure
clevidipine Correct Answer: used as an intravenous drug for hypertensive
emergencies due to it's rapid onset of action and short half-life
hypotensive agent FDA-approved for the treatment of ADHD Correct Answer:
Guanfacine (extended release) - alpha 2 receptor agonist
when prescribing benzodiazepines, only lorazepam, diazepam, or temazepam
should be considered for which patients Correct Answer: patients with hepatic
impairment
indication for lithium Correct Answer: mood stabilizer--Mania, or depressive
symptoms in bipolar disorder
important consideration when administering total parenteral nutrition peripherally
Correct Answer: can cause phlebitis in peripheral line, lower osmolarity is necessary
mechanism of action of thiazide like diuretics Correct Answer: work in the distal
tubule
In asthma patients, bronchospasms occur when an irritant interacts with: Correct
Answer: Arachidonic acid
Answers
Location of H4 receptors Correct Answer: eosinophils, neutrophils and T cells
second-generation antihistamine that cannot be removed by hemodialysis Correct
Answer: cetirizine (hydrochloride) aka Zyrtec
diagnosis of enterobiasis Correct Answer: caused by small threadlike pinworm,
Enterobius vermicularis, perianal cutaneous irritation, may result in dermatitis and
secondary bacterial infections. DIAGNOSIS: perianal swab using adhesive tape,
examined for eggs
treatment modalities of tuberculosis Correct Answer: directly observed therapy,
adherence to drug regimen, important for anything less than daily doses, highly
susceptible to drug-drug interactions
according to universal prescribing alerts for ahminoglycosides, extended use
increases risk for infection by which pathogens Correct Answer: C.difficile-
associated diarrhea and pseudomembranous colitis with extended use
mode of administration of dactinomycin Correct Answer: vesicants, should be
administered only by intravenous route to prevent extravasation. If extravasation
occurs administration should be stopped, monitor for signs of infection & bleeding.
Myelosuppression
FDA- approved indication for methotrexate Correct Answer: meningeal leukemia,
trophoblastic neoplasms. Breast Cancer
Synthetic muscarinic receptor antagonist that possesses M3 receptor selectivity
Correct Answer: darifenacin & solifenacin
Autonomic agents associated simulation of insulin production, increase
glycogenolysis in the liver and complicate the management of diabetes mellitus
, Correct Answer: may stimulate insulin production- increase glycogenolysis in the
liver and complicate the management--sympathomimetic autonomic agents
most commonly used therapy for iron-deficiency anemia Correct Answer: ferrous
sulfate
fatalities have occurred with the test dose of which drug Correct Answer: iron
dextran
antilipemic agent that targets triglycerides Correct Answer: Fibrates
mechanism of action calcium-channel blocking agents Correct Answer: act on
calcium channels in large vessels to produce vasodilation and subsequent reduction
in blood pressure
clevidipine Correct Answer: used as an intravenous drug for hypertensive
emergencies due to it's rapid onset of action and short half-life
hypotensive agent FDA-approved for the treatment of ADHD Correct Answer:
Guanfacine (extended release) - alpha 2 receptor agonist
when prescribing benzodiazepines, only lorazepam, diazepam, or temazepam
should be considered for which patients Correct Answer: patients with hepatic
impairment
indication for lithium Correct Answer: mood stabilizer--Mania, or depressive
symptoms in bipolar disorder
important consideration when administering total parenteral nutrition peripherally
Correct Answer: can cause phlebitis in peripheral line, lower osmolarity is necessary
mechanism of action of thiazide like diuretics Correct Answer: work in the distal
tubule
In asthma patients, bronchospasms occur when an irritant interacts with: Correct
Answer: Arachidonic acid