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2026 RN Pharmacology Exam Prep Guide: Key Topics, Study Tips & Top Nursing Schools

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Prepare effectively for the 2026 RN Pharmacology exam with this comprehensive study guide covering high‑yield drug concepts, safe medication administration principles, and core pharmacology knowledge. Designed for nursing students and aspiring registered nurses, the guide breaks down essential drug classes, common side effects, and critical nursing considerations. It also includes proven study strategies and representative practice questions to build confidence and clinical judgment. Whether you’re in a BSN, ADN, or RN‑to‑BSN pathway, mastering pharmacology is vital for safe patient care and NCLEX success. Plus, explore five respected nursing schools known for strong pharmacology coursework and NCLEX pass rates.

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Institution
Saint Mary\\\'S University Of Minnesota
Course
2026 RN Pharmacology

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1|Page


RN Pharmacology A Relias (NEW UPDATED VERSION) LATEST ACTUAL EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED QUESTIONS AND ANSWERS)-
GUARANTEED PASS A+
RN Pharmacology A – Practice Questions
1-10 Cardiovascular Drugs

1. Which of the following is a calcium channel blocker?
A) Lisinopril
B) Amlodipine
C) Metoprolol
D) Furosemide
Answer: B
Rationale: Amlodipine relaxes vascular smooth muscle by blocking calcium channels.
2. A patient on metoprolol should monitor:
A) Blood glucose
B) Heart rate
C) Sodium levels
D) Oxygen saturation
Answer: B
Rationale: Beta-blockers can cause bradycardia; monitor pulse and hold if <60 bpm.
3. Spironolactone is classified as:
A) Loop diuretic
B) Thiazide diuretic
C) Potassium-sparing diuretic
D) Osmotic diuretic
Answer: C
Rationale: Spironolactone retains potassium while promoting sodium excretion.
4. A patient taking furosemide should monitor for:
A) Hyperkalemia
B) Hypokalemia
C) Bradycardia
D) Hypernatremia
Answer: B
Rationale: Loop diuretics increase potassium excretion.
5. Lisinopril can cause which adverse effect?
A) Dry cough
B) Bradycardia
C) Constipation
D) Tremors
Answer: A
Rationale: ACE inhibitors increase bradykinin, leading to a persistent dry cough.
6. Nitroglycerin tablets should be stored:
A) In a cool, dark place
B) In the refrigerator


2026 2027 GRADED A+

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C) Near a heat source
D) In water
Answer: A
Rationale: Nitroglycerin is light and heat-sensitive.
7. Patient teaching for digoxin includes:
A) Skip dose if feeling well
B) Check apical pulse before administration
C) Avoid monitoring potassium
D) Take with grapefruit juice
Answer: B
Rationale: Digoxin slows heart rate; hold if pulse <60 bpm.
8. Amlodipine can cause:
A) Hypotension
B) Hyperglycemia
C) Hyperkalemia
D) Diarrhea only
Answer: A
Rationale: Calcium channel blockers can lower blood pressure.
9. Beta-blockers are contraindicated in patients with:
A) Asthma
B) Hypertension
C) Heart failure
D) Angina
Answer: A
Rationale: Nonselective beta-blockers can exacerbate bronchospasm.
10. A patient taking hydrochlorothiazide should:
A) Increase potassium-rich foods
B) Avoid fluids
C) Reduce fiber intake
D) Take with milk only
Answer: A
Rationale: Thiazide diuretics may cause hypokalemia.



11–20: Respiratory Drugs

11. Albuterol is primarily used for:
A) Chronic bronchitis only
B) Acute asthma relief
C) COPD prevention
D) Allergic rhinitis
Answer: B
Rationale: Albuterol is a short-acting beta-2 agonist for acute bronchospasm.
12. Common side effects of albuterol include:
A) Tremors, tachycardia
B) Bradycardia


2026 2027 GRADED A+

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C) Constipation
D) Edema
Answer: A
Rationale: Beta-2 stimulation can cause these effects.
13. Ipratropium is classified as:
A) Beta-2 agonist
B) Anticholinergic
C) Corticosteroid
D) Leukotriene inhibitor
Answer: B
Rationale: Ipratropium blocks muscarinic receptors to relax bronchial muscles.
14. Montelukast is indicated for:
A) Acute asthma attacks
B) Long-term asthma prophylaxis
C) COPD exacerbation only
D) Bacterial infection
Answer: B
Rationale: Montelukast prevents chronic asthma symptoms.
15. Inhaled corticosteroids require:
A) Rinsing mouth after use
B) Taking only when symptomatic
C) Avoiding bronchodilators
D) Combining with NSAIDs
Answer: A
Rationale: Prevents oral candidiasis and irritation.
16. Theophylline toxicity may present with:
A) Tachycardia, nausea, CNS excitation
B) Bradycardia
C) Hypotension
D) Constipation
Answer: A
Rationale: Narrow therapeutic window requires monitoring serum levels.
17. Oxygen therapy requires monitoring:
A) Pulse oximetry
B) Glucose
C) Sodium
D) Temperature
Answer: A
Rationale: Ensures adequate oxygen saturation.
18. Albuterol should be used:
A) Before corticosteroid inhalers
B) After meals only
C) Only once daily
D) With antacids
Answer: A
Rationale: Opens airways for better steroid delivery.



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19. Long-term corticosteroid use may cause:
A) Osteoporosis
B) Bradycardia
C) Hypoglycemia
D) Diarrhea
Answer: A
Rationale: Chronic steroid use reduces bone density.
20. Patient teaching for inhalers includes:
A) Shake inhaler before use
B) Hold breath after inhalation
C) Rinse mouth if steroid
D) All of the above
Answer: D
Rationale: Ensures proper administration and reduces side effects.



21–30: Antibiotics

21. Penicillin is effective against:
A) Bacteria
B) Viruses
C) Fungi
D) Parasites
Answer: A
Rationale: Inhibits bacterial cell wall synthesis.
22. Adverse effects of antibiotics include:
A) GI upset, rash, hypersensitivity
B) Hypotension
C) Bradycardia only
D) Hair loss
Answer: A
Rationale: GI upset and allergies are common.
23. Cephalosporins may cross-react in patients allergic to:
A) Penicillin
B) Macrolides
C) Tetracyclines
D) Fluoroquinolones
Answer: A
Rationale: Cross-sensitivity risk exists.
24. Aminoglycosides (e.g., gentamicin) require monitoring:
A) Liver function
B) Peak/trough levels
C) BP
D) Blood sugar
Answer: B
Rationale: Nephrotoxicity and ototoxicity require level monitoring.


2026 2027 GRADED A+

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Institution
Saint Mary\\\'S University Of Minnesota
Course
2026 RN Pharmacology

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