, b. Most single-celled organisms require a microscope to render them visible,
but some
bacterial cells are large enough to be seen with naked eyes.
c. Microbes function as individual entities.
d. Many microbes form complex multicellular assemblages.
e. Viruses are not considered as microbial cells.
ANS: C DIF: Easy REF: 1.1 TOP: I.A.i | I.A.ii
MSC: Remembering
6. Which of the following statements is FALSE?
a. A genome is the total genetic information contained in an organism’s
chromosomal DNA.
b. If a microbe’s genome includes genes for nitrogenase, that microbe probably can
fix nitrogen.
c. By comparing DNA sequences of different organisms, we can figure out how
closely
related they are.
d. Fred Sanger developed the first applicable DNA sequencing method.
e. Fred Sanger completed the sequences of Haemophilus influenzae.
ANS: E DIF: Easy REF: 1.1 TOP: I.B
MSC: Remembering
7. The first cellular genomes to be sequenced were those of:
a. humans d. prions
b. bacteria e. fungi
c. viruses
ANS: B DIF: Easy REF: 1.1 TOP: I.B.i
MSC: Remembering
8. The environment of early Earth may have contained all of the following EXCEPT:
a. ferrous iron d. oxygen
b. methane e. hydrogen gas
c. ammonia
ANS: D DIF: Easy REF: Special Topic
1.1 TOP: II.D MSC: Remembering
9. The development of the theory of the ―RNA world‖ resulted from the discovery of:
a. archaea d. ribozymes
b. prions e. endosymbionts
c. bacteria
ANS: D DIF: Medium REF: Special Topic
1.1 TOP: II.D MSC: Remembering
10. Which microbes may resemble those of the earliest life forms?
a. archaea d. cyanobacteria
b. photosynthetic algae e. protists
c. viruses
ANS: A DIF: Medium REF: Special Topic
1.1 TOP: II.D MSC: Remembering
11. Early metabolism may have been catalyzed by:
a. DNA d. amino acids
b. RNA e. carbohydrates
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, c. protein
ANS: B DIF: Medium REF: Special Topic
1.1 TOP: II.D MSC: Remembering
12. Which of the following diseases accounts for more than half of all human mortality?
a. cardiovascular disease d. microbial disease
b. cancer e. strokes
c. accidents
ANS: D DIF: Easy REF: 1.2 TOP: II.A
MSC: Remembering
13. Which century is known as the golden age of microbiology?
a. the seventeenth d. the twentieth
b. the eighteenth e. the twenty-
first
c. the nineteenth
ANS: C DIF: Easy REF: 1.2 TOP: II.A
MSC: Remembering
14. All of the following have been found in mummies and tomb art EXCEPT:
a. tuberculosis d. smallpox
b. polio e. AIDS
c. leprosy
ANS: E DIF: Medium REF: 1.2 TOP: II.A.i
MSC: Remembering
15. How did European invaders to North America kill much of the native population?
a. tuberculosis d. HIV
b. leprosy e. bubonic plague
c. smallpox
ANS: C DIF: Medium REF: 1.2 TOP: II.A.i
MSC: Remembering
16. Nightingale:
a. is better known as the founder of professional nursing
b. was the first to use disinfectant to demonstrate the significance of aseptic
technique
c. developed the pie chart of mortality data during the Crimean War
d. performed the first controlled experiment on the chemical conversion of
matter, known
today as chemotherapy
e. all of the above
ANS: A DIF: Easy REF: 1.2 TOP: II.A.ii
MSC: Remembering
17. Who developed the concept of medical statistics?
a. Francis Crick d. Louis Pasteur
b. Florence Nightingale e. Alexander Fleming
c. Edward Jenner
ANS: B DIF: Easy REF: 1.2 TOP: II.A.ii
MSC: Remembering
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, 18. The first person to visualize individual microbes was:
a. Antonie van Leeuwenhoek d. Lady Montagu
b. Robert Hooke e. Edward Jenner
c. Louis Pasteur
ANS: A DIF: Easy REF: 1.2 TOP: II.B.ii
MSC: Remembering
19. Which technique was developed to distinguish bacteria from human cells?
a. Gram stain d. DNA sequencing
b. electron microscopy e. polymerase chain reaction
(PCR)
c. X-ray diffraction
ANS: A DIF: Medium REF: 1.2 TOP: II.B.ii
MSC: Remembering
20. How is most sterilization performed for the controlled study of microbes?
a. boiling d. autoclaving
b. pasteurization e. irradiation
c. filter sterilization
ANS: D DIF: Medium REF: 1.2 TOP: II.C.iii.a
MSC: Remembering
21. Microbes can shape human history via:
a. lithotrophic activities d. production of
cheese
b. production of alcoholic beverages e. all of the above
c. diseases that they cause
ANS: E DIF: Medium REF: 1.2 TOP: II.A
MSC: Understanding
22. Suppose Pasteur’s swan-necked flasks containing boiled broth became cloudy 24 hours
after boiling. Which choice could best explain the turbidity or cloudiness in the broth
without supporting spontaneous generation?
a. Endospores in the broth survived boiling and grew after the broth cooled.
b. Contaminating organisms in the broth killed by boiling became alive again after
the broth
cooled.
c. Chemicals in the broth came together to form living organisms.
d. The broth allowed light to pass through it with less interference after boiling.
e. Solid material in the broth dissolved during boiling.
ANS: A DIF: Difficult REF: 1.2 TOP: II.C.ii.b
MSC: Applying
23. Robert Koch’s greatest accomplishment in the field of medical bacteriology was with:
a. Escherichia coli d. rabies
b. Bacillus subtilis e. smallpox
c. Mycobacterium
tuberculosis
ANS: C DIF: Medium REF: 1.3 TOP: III.B.i
MSC: Remembering
24. The use of agar as the gelling agent in solid media was suggested by:
a. Robert Koch d. Louis Pasteur
b. Ignaz Semmelweis e. Richard Petri
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