What is the monoamine hypothesis of depression? -correct answers It theorizes that depression
is caused by a deficiency in monoamine neurotransmission, while mania is due to an excess.
What is a key prescribing considera on for an depressants in bipolar disorder? -correct answers
An depressants should not be given as monotherapy; they must be combined with a mood
stabilizer to avoid inducing mania.
What should be monitored when prescribing SNRIs to breas eeding pa ents? -correct answers
Infant irritability.
What factors should be considered when prescribing an depressants? -correct answers Client
preference, prior treatment response, an cipated adverse effects, comorbidi es, half-life,
interac ons, and cost.
What should be done if the ini al an depressant does not work? -correct answers First,
increase the dose; if that fails, switch to a different drug in the same class, then try a drug in a
different class, and possibly add a second medica on.
What is the recommended dose adjustment for older pa ents taking citalopram and
escitalopram? -correct answers They should receive half the usual dose.
Which SSRI has the least CYP interac ons? -correct answers Escitalopram (Lexapro).
, Which SSRI is considered good for forge ul pa ents? -correct answers Fluoxe ne, due to its 2-3
day half-life.
What is the longest-ac ng an depressant? -correct answers Fluoxe ne, with a half-life of 1-2
weeks.
What is discon nua on syndrome and which medica on is more likely to cause it? -correct
answers Discon nua on syndrome occurs when stopping an an depressant, and paroxe ne is
more likely to cause it.
Which an depressant is safe during nursing and pregnancy? -correct answers Sertraline.
What is serotonin syndrome? -correct answers A condi on that occurs when two serotonergic
drugs are used together, leading to symptoms such as mental status changes, autonomic
instability, neuromuscular symptoms, seizures, and gastrointes nal symptoms.
What is the treatment for serotonin syndrome? -correct answers Stop the medica on, provide
suppor ve care, and use benzodiazepines.
What is the black box warning for MAOIs? -correct answers They carry a warning for suicidal
idea on in children, adolescents, and young adults.
What is the half-life of MAOIs? -correct answers 2-4 hours.
What is the black box warning for SSRIs? -correct answers They carry a warning for suicidal
tendencies.
is caused by a deficiency in monoamine neurotransmission, while mania is due to an excess.
What is a key prescribing considera on for an depressants in bipolar disorder? -correct answers
An depressants should not be given as monotherapy; they must be combined with a mood
stabilizer to avoid inducing mania.
What should be monitored when prescribing SNRIs to breas eeding pa ents? -correct answers
Infant irritability.
What factors should be considered when prescribing an depressants? -correct answers Client
preference, prior treatment response, an cipated adverse effects, comorbidi es, half-life,
interac ons, and cost.
What should be done if the ini al an depressant does not work? -correct answers First,
increase the dose; if that fails, switch to a different drug in the same class, then try a drug in a
different class, and possibly add a second medica on.
What is the recommended dose adjustment for older pa ents taking citalopram and
escitalopram? -correct answers They should receive half the usual dose.
Which SSRI has the least CYP interac ons? -correct answers Escitalopram (Lexapro).
, Which SSRI is considered good for forge ul pa ents? -correct answers Fluoxe ne, due to its 2-3
day half-life.
What is the longest-ac ng an depressant? -correct answers Fluoxe ne, with a half-life of 1-2
weeks.
What is discon nua on syndrome and which medica on is more likely to cause it? -correct
answers Discon nua on syndrome occurs when stopping an an depressant, and paroxe ne is
more likely to cause it.
Which an depressant is safe during nursing and pregnancy? -correct answers Sertraline.
What is serotonin syndrome? -correct answers A condi on that occurs when two serotonergic
drugs are used together, leading to symptoms such as mental status changes, autonomic
instability, neuromuscular symptoms, seizures, and gastrointes nal symptoms.
What is the treatment for serotonin syndrome? -correct answers Stop the medica on, provide
suppor ve care, and use benzodiazepines.
What is the black box warning for MAOIs? -correct answers They carry a warning for suicidal
idea on in children, adolescents, and young adults.
What is the half-life of MAOIs? -correct answers 2-4 hours.
What is the black box warning for SSRIs? -correct answers They carry a warning for suicidal
tendencies.
