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NR546 PSYCHOPHARM MIDTERM EXAM QUESTIONS AND CORRECT ANSWERS 2025/2026

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How does the orbitofrontal cortex (OFC) affect the amygdala? -correct answers inhibits and activates the amygdala Wernicke's area is associated with which of the following? -correct answers speech comprehension The limbic system is associated with which of the following -correct answers emotion and learning Which brain structure is most associated with long term memory? -correct answers hippocampus When prescribing psychotropic medications, the PMHNP knows that these medications work within which specific areas? -correct answers mood

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NR546 Psychopharm
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NR546 Psychopharm

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How does the orbitofrontal cortex (OFC) affect the amygdala? -correct answers inhibits and
ac vates the amygdala



Wernicke's area is associated with which of the following? -correct answers speech
comprehension



The limbic system is associated with which of the following -correct answers emo on and
learning



Which brain structure is most associated with long term memory? -correct answers
hippocampus



When prescribing psychotropic medica ons, the PMHNP knows that these medica ons work
within which specific areas? -correct answers mood



Which of the following are involved in regula ng neurotransmission via excita on-secre on
coupling? -correct answers voltage-sensi ve sodium channels and voltage-sensi ve calcium
channels



What system influences the length of me for a drug to achieve efficacy? -correct answers signal
transduc on cascades



One of the signal transduc on cascades, pass the message from a first receptor to a second
messenger. -correct answers G protein linked systems

,Human central nervous system communica on at synapses is which of the following? -correct
answers chemical



Which of the following is an excitatory neurotransmi er? -correct answers glutamate



Which statement correctly pairs the pharmacodynamic effect with its defini on? -correct
answers antagonist effect - drug binds to receptor, but does not ac vate a response



A major current hypothesis for the cause of schizophrenia proposes that N-methyl-d-aspartate
(NMDA) receptors may be which of the following?

Correct! -correct answers hypofunc onal



Which medica on is least associated with weight gain? -correct answers aripiprazole



Which dopamine pathway is associated with posi ve symptoms of schizophrenia? -correct
answers mesolimbic pathway



Which pathway is associated with nega ve symptoms? -correct answers The mesocor cal
pathway



Is part of the extrapyramidal nervous system and associated with extrapyramidal symptoms
(EPS) -correct answers nigrostriatal pathway



This pathway is associated with hyperprolac nemia. -correct answers The tuberoinfundibular
pathway

,A 34-year old male recently began experiencing breast secre ons while receiving risperidone .
Which dopamine pathway is associated with this side effect? -correct answers
tuberoinfundibular pathway



A 44-year-old woman is ini ated on an atypical an psycho c for the treatment of
schizophrenia. Regarding affinity, atypical an psycho cs demonstrate which of the following
most o en? -correct answers Atypical an psycho cs have equal posi ve symptom an psycho c
ac ons and low extrapyramidal symptoms.



is a syndrome that can be associated with several different psychiatric disorders. Symptoms
include hallucina ons, delusions, disorganized speech, disorganized behavior, and distor ons of
reality. This syndrome can affect a person's cogni on, affec ve response, communica on,
capacity to recognize reality, and ability to relate to others. -correct answers psychosis



What Diagnosis require the presence of psychosis? -correct answers schizophrenia

substance-induced psycho c disorders

schizophreniform disorder

schizoaffecive disorder

delusional disorder

brief psycho c disorder

psycho c disorder due to a medical condi on



What diagnosis has a diagnosis of psychosis as a feature? -correct answers mania

depression

cogni ve disorders

demen a



What are some posi ve symptoms? -correct answers Hallucina ons

, Delusions

Thought disorder

Hos lity

Excitability



What are some Nega ve symptoms? -correct answers Affec ve fla ening

Alogia

Anhedonia

Amo va on

Asociality



What area of the brain is associated with nega ve and affec ve symptoms? -correct answers
Mesocor cal and ventromedial prefrontal cortex:



What area of the brain is associated with cogni ve symptoms? -correct answers Dorsolateral



What area of the brain is associated with aggressive, impulsive symptoms? -correct answers
Orbitofrontal and connec ons to the amygdala



Non-selec vely blocks dopamine D2 receptors, specifically in mesolimbic pathway. Improves
Posi ve Symptoms

Use: Acute & Chronic Schizophrenia & Psychosis -correct answers First genera on an psycho cs



are associated with movement, intelligence, abstract thinking, the ability to organize,
personality, behavior, and emo onal control. Trauma c brain injuries can result in personality
changes, difficulty controlling emo ons, and other cogni ve func ons -correct answers Frontal
Lobes

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NR546 Psychopharm
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NR546 Psychopharm

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