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Exam (elaborations)

Pathophysiology & Pharmacology (D027) – WGU – Academic Year 2025–2026 – Exam questions and answers

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This document contains exam-style questions and detailed answers covering the core topics of the WGU D027 Pathophysiology & Pharmacology course. It focuses on key pathophysiological processes, pharmacological principles, and system-based disorders commonly assessed in the exam. The material is designed to support effective revision and reinforce understanding of high-yield concepts for exam preparation.

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WGU D027 Patho Pharm
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Institution
WGU D027 Patho Pharm
Course
WGU D027 Patho Pharm

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Uploaded on
January 6, 2026
Number of pages
62
Written in
2025/2026
Type
Exam (elaborations)
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Questions & answers

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WGU D027 Patho Pharm Exam Questions and Answers
(Verified Answers) Latest Update 2026

How are multi-factorial diseases affected by genetics? - correct answers
risk for a multifactorial trait or condition depends on how close you are
to a family member with the trait or condition. (ex: if sibling has it=higher
risk)



Describe Hutchinson-Gilford Progeria Syndrome. Explain the signs and
symptoms. How is it diagnosed and treated? - correct answers -
progressive genetic disorder - children age rapidly

-occurs randomly, not inherited



S/S:

-slow growth & hair loss in 1st/2nd year of life

-short stature or slow growth

-delayed tooth development or failure to develop normally

-skin wrinkles/dryness

-enlarged head, hearing loss, high pitched voice, incomplete sexual
maturation, joint stiffness, loss of muscle, osteoarthritis, taut skin

,Dx:

-gentic test for LMNA

-physical assessment



Tx:

- no cure

-PT/OT

-Statins - decrease liver production of harmful cholesterol

-NSAIDS - relieve pain and decrease inflammation

-meds to strengthen/build bones

PRNs for anxiety - correct answers f*cking benzos baby

- alprazolam, chlordiazepoxide, clonazepam, diazepam, lorazepam



What are the body's compensatory mechanisms? - correct answers -
Autonomic nervous system

- Cardiac rate/contractility

- Venous return, vasoconstriction

,- Baroreceptor reflexes (homeostatic mech to maintain BP)

- Chemoreceptor reflexes (regulates respiration, cardiac output, regional
blood flow)



What are the two recs for genetic testing? - correct answers -carrier
screening - determines if a person is a carrier for specific autosomal
recessive diseases



-prenatal diagnostic such as amniocentesis



How many leading causes of death do genetics play a role in? - correct
answers 9/10



Give some examples of live vaccines. Are they safe to use in pregnancy? -
correct answers YES WHEN PREGGO:

- Flu - safe for all pregnant women

- pneumococcal

- hep A/B

- meningococcal

, -tdap - btwn 27-36 weeks, w/ each pregnancy



CONTRAINDICATED:

- varicella (live)

- MMR (live)



What is the primary function of the heart? - correct answers -pump
oxygenated blood/nutrients/hormones to body

-maintaining BP

- receiving deoxygenated blood and carrying metabolic waste products from
body



Primary hypertension vs secondary hypertension - correct answers
Primary htn: cause is unknown



Secondary htn: caused by another condition such as kidney disease, adrenal
disease, thyroid problems and OSA

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