ANCC Domain 1 questions Trusted Exam Prep |
Accurate & Updated 2025–2026
What direct-acting dopamine receptor agonist is recommended to be used in the treatment of
neuroleptic malignant syndrome (NMS) to help lower the dopamine receptor blockade?
A. Dantrolene (Dantrium)
B. Benztropine (Cogentin)
C. Bromocriptine (Parlodel)
D. Trihexyphenidyl (Artane) - correct answer -C. Bromocriptine (Parlodel)
A 74 y/o female present for an evaluation. The psychiatric nurse practitioner has the patient
complete the mini mental status examination and clock drawing. The patient is unable to
correctly draw the face of the clock. Which area of the brain is likely to have compromised
functioning?
A. Corpus callosum
B. Wernicke's Area
C. Left Hemisphere
D. Right Hemisphere - correct answer -D. Right Hemisphere
Which of the following statements reflects current understanding of neurodevelopment and
best explains risk-taking behaviors of adolescent males?
A. Stimulant and substance use impairs judgment and cognitive appraisal
B. Pruning of serotonin circuits in the adolescent brain is associated with increased impulsivity
C. Maturation of the prefrontal cortex continues into mid-20s and early 30s
D. Hormonal flooding, especially testosterone and oxytocin, increase dopamine levels in the
brain - correct answer -C. Maturation of the prefrontal cortex continues into mid-20s and early
30s
, What cytochrome (CYP) enzyme is implicated as a tobacco inducer when an individual is treated
on clozapine?
A. 2C19
B. 1A2
C. 2C9
D. 2D6 - correct answer -B. 1A2
As a psychiatric mental health nurse practitioner, you are aware of antipsychotic medication side
effects. Which of the following side effects of antipsychotic medications has an insidious,
delayed-onset typically 1 to 2 years after initiation of the medication?
A. Sedation
B. Weight gain
C. Tardive dyskinesia
D. Dry mouth - correct answer -C. Tardive dyskinesia
Which mood stabilizer is most associated with a potentially life-threatening rash?
A. Divalproex (depakote)
B. Carbamazepine (tegretol)
C. Lithium (eskalith)
D. Lamotrigine (lamictal) - correct answer -D. Lamotrigine (lamictal)
The psychiatric-Mental Health Nurse Practitioner would expect to see which of the following
during a physical exam for a patient with bulimia nervosa?
A. Alopecia areata
B. Tachycardia
C. Erosion of dental enamel
D. Obesity - correct answer -C. Erosion of dental enamel
Accurate & Updated 2025–2026
What direct-acting dopamine receptor agonist is recommended to be used in the treatment of
neuroleptic malignant syndrome (NMS) to help lower the dopamine receptor blockade?
A. Dantrolene (Dantrium)
B. Benztropine (Cogentin)
C. Bromocriptine (Parlodel)
D. Trihexyphenidyl (Artane) - correct answer -C. Bromocriptine (Parlodel)
A 74 y/o female present for an evaluation. The psychiatric nurse practitioner has the patient
complete the mini mental status examination and clock drawing. The patient is unable to
correctly draw the face of the clock. Which area of the brain is likely to have compromised
functioning?
A. Corpus callosum
B. Wernicke's Area
C. Left Hemisphere
D. Right Hemisphere - correct answer -D. Right Hemisphere
Which of the following statements reflects current understanding of neurodevelopment and
best explains risk-taking behaviors of adolescent males?
A. Stimulant and substance use impairs judgment and cognitive appraisal
B. Pruning of serotonin circuits in the adolescent brain is associated with increased impulsivity
C. Maturation of the prefrontal cortex continues into mid-20s and early 30s
D. Hormonal flooding, especially testosterone and oxytocin, increase dopamine levels in the
brain - correct answer -C. Maturation of the prefrontal cortex continues into mid-20s and early
30s
, What cytochrome (CYP) enzyme is implicated as a tobacco inducer when an individual is treated
on clozapine?
A. 2C19
B. 1A2
C. 2C9
D. 2D6 - correct answer -B. 1A2
As a psychiatric mental health nurse practitioner, you are aware of antipsychotic medication side
effects. Which of the following side effects of antipsychotic medications has an insidious,
delayed-onset typically 1 to 2 years after initiation of the medication?
A. Sedation
B. Weight gain
C. Tardive dyskinesia
D. Dry mouth - correct answer -C. Tardive dyskinesia
Which mood stabilizer is most associated with a potentially life-threatening rash?
A. Divalproex (depakote)
B. Carbamazepine (tegretol)
C. Lithium (eskalith)
D. Lamotrigine (lamictal) - correct answer -D. Lamotrigine (lamictal)
The psychiatric-Mental Health Nurse Practitioner would expect to see which of the following
during a physical exam for a patient with bulimia nervosa?
A. Alopecia areata
B. Tachycardia
C. Erosion of dental enamel
D. Obesity - correct answer -C. Erosion of dental enamel
