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Pathophysiology | Questions &
Answers | Grade A | 100% Correct -
Portage Learning
Gastrointestinal Disorders
Question:
Peptic Ulcer Disease (PUD) encompasses:
Answer:
A group of ulcerative disorders in the upper GI tract that are exposed to acid-
pepsin secretions.
Question:
Peptic ulcers affect which layers of the stomach or duodenum?
Answer:
All.
,Question:
Most common forms of PUD (2)
Which is more common?
Answer:
Duodenal and gastric ulcers.
Duodenal ulcers are 5x more common than gastric ulcers.
Question:
Duodenal ulcers age and sex:
Gastric ulcers age and sex
Answer:
30 to 60, more likely men
Middle-aged and older men and women.
,Question:
What happens If peptic ulcer is enough to erode into the muscaris layer?
Answer:
It will be replaced by scar tissue.
Question:
Two most common causes of PUD:
Both show what?
Answer:
-H. Pylori
-Aspirin, NSAIDS
Both impair the mechanisms that protect the gastric mucosa from the
damaging effects of acid.
, Question:
How does H. pylori cause PUD?
NSAIDS?
Answer:
Infection causes inflammation
-Release of cytokines that contribute to mucosal damage.
Inhibit prostaglandin synthesis
Question:
Other risk factors for PUD? (7)
Answer:
-Advancing age
-Prior history of PUD
-Concurrent use of warfarin and multiple NSAIDS
-Corticosteroids
-Smoking
-Alcohol
-Stress