Complete Solutions 2025|2026 Latest
Update
cardiovascular problems due to - correct answer-anthracyclines
(doxoruvbicin, epirubicin)
target therapies(bavacizumab and trastuzumab)
mitoxantrone
hearing loss - correct answer-platinum based chemotherapies (cisplatin
and carboplatin)
Alkylating agents - correct answer-cyclophosphamide
carmustine
chlorambucil
increases the risk of MDS & AML within 2 years
Platinum-based agents - correct answer-cisplatin
,carboplatin
increases the risk of AML
Topoisomerase II inhibitors - correct answer-Etoposide
mitoxantrone
increases the risk of AML within 2-3 years
Targeted therapy - correct answer-vemurafenib
dabrafenib
increase risk of squamous cell carcinoma
thermoregulatory center - correct answer-in the hypothalamus controls
the rise and fall of the body's temperature
cancer that causes fever - correct answer-usually in the lymph system,
bone and the liver.
,Kubler-Ross stages of grief - correct answer-1. Denial
2. Anger
3. Bargaining
4. Depression
5. Acceptance
cancer - correct answer-irregular cell growth and production
carcinogenesis - correct answer-process of normal genes are damaged,
so cell lose control mechanism and proliferate out of control.
familial carcinogenesis - correct answer-cancer suppressor genes that
are present normally but when changed cause cancer by their absence.
breast cancer is ex.
viral carcinogenesis - correct answer-hep B virus, human T-cell
leukemia-lymphoma virus, human papilloviruses and epstein-barr virus
, bacterial carcinogenesis - correct answer-helicobacter pylori is
associated with mucosa-associated lymphoid tissue lymphoma
chemical carcinogenesis - correct answer-induced by chemical/toxin
exposure ex lung cancer from smoking
environmental carcinogenesis - correct answer-from secondary smoke
physical carcinogenesis - correct answer-squasmous cell cancer caused
by exposure to UA of the sun
steps in metastatic sequence - correct answer-1-tumor growth and
neovascularization
2-tumor cell invasion
3-detachment and embolism of tumor cell aggregates
4-arrest in distant organ capillary beds
5-extravasation