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FM EORE Endocrinology & Hematology Review | 80+ Questions with Answers | MED313 | Diabetes, Thyroid, Anemia, Coagulopathies

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This expert-verified study guide features over 80 board-style multiple-choice questions and answers aligned with the Family Medicine End of Rotation Exam (EORE) for Endocrinology and Hematology. Developed for the 2025 academic year, this resource is ideal for students in MED313 or similar rotations that emphasize clinical reasoning in chronic disease and blood disorders. Each question emphasizes real-world clinical application, diagnostic criteria, lab interpretations, and treatment protocols encountered in family and internal medicine practice. Key endocrine topics covered include: Diabetes Mellitus (T1DM & T2DM): pathophysiology, insulin regimens, complications (DKA, HHS), and diagnostic criteria (A1c, FBG, GTT) Adrenal Disorders: Addison’s disease (primary adrenal insufficiency), Cushing’s syndrome, ACTH differentiation, and pharmacologic management Thyroid Disorders: Graves' disease, thyroiditis, pituitary adenoma, Hashimoto’s thyroiditis, and TSH/T4 lab interpretation Pharmacology: Use of levothyroxine, methimazole, PTU, hydrocortisone, fludrocortisone, and insulin therapies Key hematology topics include: Anemias: differentiation of macrocytic (B12, folate), microcytic (iron deficiency, thalassemia), and normocytic types Coagulopathies: Hemophilia A and B, von Willebrand Disease — including factor deficiencies, aPTT/platelet findings, and DDAVP/clotting factor treatments Leukemia Subtypes: ALL, AML, CML, CLL with key age groups and diagnostic clues (Auer rods, Philadelphia chromosome) Lymphoma: Hodgkin's lymphoma (Reed-Sternberg cells, B symptoms, biopsy staging) Myeloproliferative disorders: Polycythemia vera (JAK2 mutation, hyperviscosity symptoms, phlebotomy) This resource is especially useful for students in: Physician Assistant (PA) programs preparing for the Endo/Heme EORE Medical students (MD/DO) during primary care, endocrinology, or internal medicine rotations Nursing and Nurse Practitioner (NP) students studying endocrine and hematologic disorders International medical graduates preparing for USMLE Step 2 CK or PANCE This comprehensive guide enhances mastery through clinically relevant Q&A content that mirrors exam formats and real-life scenarios, reinforcing active recall and diagnostic decision-making. Keywords: endocrinology, hematology, diabetes mellitus, insulin therapy, DKA, adrenal insufficiency, Cushing syndrome, hypothyroidism, hyperthyroidism, anemia, B12 deficiency, iron deficiency, hemophilia, von Willebrand disease, leukemia, lymphoma, polycythemia vera, JAK2, thyroid labs, pituitary adenoma, ACTH, clotting disorders

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Uploaded on
December 18, 2025
Number of pages
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Written in
2025/2026
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FM EORE Endo & Heme 2025 Expert
Verified | Ace the Test



T1DM - 🧠 ANSWER ✔✔- Destruction of beta cells (antibodies)


- Adolescents

- Fatigue, polydipsia, polyuria

- Requires insulin

- Basal long acting insulin (glargine or determir)

- Pre-meal rapid acting insulin (lisper or aspart)

- DKA (BS <1000, hypokalemic)


T2DM - 🧠 ANSWER ✔✔-- Insulin resistance related to obesity


- Fatigue, polydipsia, polyuria

, - Diet, exercise, wt loss

- Metformin, sulfonylurea

- Insulin if HbA1c >9%

- HHS (BS >1000, hypokalemic)


Diagnosing diabetes - 🧠 ANSWER ✔✔- 2 FBGs >126


- 1 glucose level >200 w/ symptoms

- HA1c >6.5%

- Positive 2 hr oral GTT


Adrenal insufficiency - 🧠 ANSWER ✔✔- 1°: Addison disease


- *Hypocortisiolism*

- Weakness, fatigue, anorexia, weight loss

- Hyperpigmentation (1° disease)

- *Hyponatremia and hyperkalemia* (1° disease)

- ↑ ACTH = 1° disease

- ↓ ACTH = 2° disease

- Hydrocortisone

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