ENDOCRINE SYSTEM PHYSIOLOGY LAB
QUESTIONS AND CORRECT ANSWERS
WhichA2rat(s)A2wasA2euthyroidA2withoutA2anyA2injections?A2-A2Ans--theA2normalA2rat
AnA2abnormallyA2highA2levelA2ofA2whichA2ofA2theA2followingA2willA2resultA2inA2goiter?A2-
A2Ans--TSH
WhyA2didA2theA2TSHA2haveA2NOA2effectA2onA2theA2BMRA2ofA2theA2thyroidectomizedA2rat?
A2-A2Ans--TheA2ratA2isA2missingA2itsA2thyroidA2gland.
TheA2injectionA2ofA2TSHA2resultedA2inA2goiterA2inA2_______.A2-A2Ans--
theA2normalA2ratA2andA2theA2hypophysectomized
PropylthiouracilA2injectionsA2resultedA2inA2goiterA2formationA2inA2_______.A2-A2Ans--
theA2normalA2rat
WhichA2ofA2theA2followingA2isA2INCORRECTLYA2matchedA2withA2itsA2secretingA2organ?A2-
A2Ans--TSHA2-A2posteriorA2pituitary
AA2decreaseA2inA2theA2levelA2ofA2thyroxineA2wouldA2increaseA2theA2secretionA2ofA2______
_.A2-A2Ans--bothA2TSHA2andA2TRH
AA2hypophysectomizedA2ratA2isA2missingA2itsA2_______.A2-A2Ans--pituitaryA2gland
ThyroxineA2isA2aA2_______.A2-A2Ans--slow-actingA2hormoneA2thatA2entersA2theA2nucleus
WhichA2ofA2theA2followingA2hormonesA2isA2regulatedA2byA2aA2positiveA2feedbackA2mechani
sm?A2-A2Ans--oxytocin
WhichA2ratA2hadA2theA2fastestA2basalA2metabolicA2rateA2(BMR)?A2-A2Ans--
TheA2normalA2ratA2hadA2theA2fastestA2BMR.
[ShowA2responseA2toA2predictA2questionA21]A2WhyA2didA2theA2metabolicA2ratesA2differA2bet
weenA2theA2normalA2ratA2andA2theA2surgicallyA2alteredA2rats?
A2HowA2wellA2didA2theA2resultsA2compareA2withA2yourA2prediction?A2-A2Ans--
TheA2metabolicA2rateA2wasA2fasterA2forA2theA2normalA2ratA2thanA2forA2theA2affectedA2rats.A2
((RememberA2toA2putA2whetherA2orA2notA2youA2predictedA2thisA2correctlyA2accordingA2toA2t
heA2questionsA2inA2theA2virtualA2lab!))
IfA2anA2animalA2hasA2beenA2thyroidectomized,A2whatA2hormone(s)A2wouldA2beA2missingA2i
nA2itsA2blood?A2-A2Ans--
CalcitoninA2andA2thyroxineA2wouldA2haveA2beenA2missingA2fromA2itsA2bloodA2ifA2itA2hadA2b
eenA2thyroidectomized.
, IfA2anA2animalA2hasA2beenA2hypophysectomized,A2whatA2effectA2wouldA2youA2expectA2toA2
seeA2inA2theA2hormoneA2levelsA2inA2itsA2body?A2-A2Ans--
ThisA2wouldA2meanA2theA2pituitaryA2glandA2wasA2removed,A2soA2theA2metabolicA2rateA2wo
uldA2goA2downA2becauseA2noA2THSA2wouldA2beA2produced.
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2normalA2rat'sA2BMR?A2-
A2Ans--TheA2metabolicA2rateA2increasedA2toA2higherA2thanA2theA2baselineA2amount.
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2thyroidectomizedA2rat'sA2BMR
?A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2thyroxineA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justright?
A2-A2Ans--
TheA2metabolicA2rateA2increasedA2butA2itA2stillA2wasA2notA2asA2highA2asA2theA2baseline.A2ItA
2comparesA2toA2theA2normalA2rat'sA2BMRA2becauseA2itA2wasA2stillA2ableA2toA2reachA2fairlyA2
normalA2ratesA2evenA2thoughA2itA2wasA2stillA2slightlyA2tooA2low.A2ThisA2meansA2thatA2theA2d
oseA2wasA2tooA2low.
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2hypophysectomizedA2rat'sA2B
MR?A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2thyroxineA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justright?
A2-A2Ans--
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2hypophysectomizedA2rat'sA2B
MR?A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2thyroxineA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justright?
WhatA2wasA2theA2effectA2ofA2thyroid-
stimulatingA2hormoneA2(TSH)A2injectionsA2onA2theA2normalA2rat'sA2BMR?A2-A2Ans--
ItA2increasedA2theA2normalA2rat'sA2BMRA2pastA2theA2levelA2itA2wasA2atA2before.
WhatA2wasA2theA2effectA2ofA2TSHA2injectionsA2onA2theA2thyroidectomizedA2rat'sA2BMR?
A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WhyA2wasA2thisA2effectA2observed?A2-A2Ans--
ThereA2wasn'tA2anyA2effectA2becauseA2theA2TSHA2influencesA2theA2thyroidA2gland,A2butA2t
hisA2ratA2hadA2theA2thyroidA2glandA2removedA2soA2itA2couldn'tA2beA2stimulatedA2byA2theA2h
ormone.A2TheA2ratA2wasA2hypothyroidic.
WhatA2wasA2theA2effectA2ofA2TSHA2injectionsA2onA2theA2hypophysectomizedA2rat'sA2BMR?
A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2TSHA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justA2right?A2-
A2Ans--
TheA2BMRA2ofA2theA2hypophysectomizedA2ratA2increasedA2butA2itA2wasA2stillA2lowerA2thanA
2theA2BMRA2ofA2theA2normalA2rat.A2ThisA2meansA2thatA2theA2doseA2wasA2tooA2low.
WhatA2wasA2theA2effectA2ofA2propylthiouracilA2(PTU)A2injectionsA2onA2theA2normalA2rat'sA2B
MR?A2WhyA2didA2thisA2ratA2developA2aA2palpableA2goiter?A2-A2Ans--
QUESTIONS AND CORRECT ANSWERS
WhichA2rat(s)A2wasA2euthyroidA2withoutA2anyA2injections?A2-A2Ans--theA2normalA2rat
AnA2abnormallyA2highA2levelA2ofA2whichA2ofA2theA2followingA2willA2resultA2inA2goiter?A2-
A2Ans--TSH
WhyA2didA2theA2TSHA2haveA2NOA2effectA2onA2theA2BMRA2ofA2theA2thyroidectomizedA2rat?
A2-A2Ans--TheA2ratA2isA2missingA2itsA2thyroidA2gland.
TheA2injectionA2ofA2TSHA2resultedA2inA2goiterA2inA2_______.A2-A2Ans--
theA2normalA2ratA2andA2theA2hypophysectomized
PropylthiouracilA2injectionsA2resultedA2inA2goiterA2formationA2inA2_______.A2-A2Ans--
theA2normalA2rat
WhichA2ofA2theA2followingA2isA2INCORRECTLYA2matchedA2withA2itsA2secretingA2organ?A2-
A2Ans--TSHA2-A2posteriorA2pituitary
AA2decreaseA2inA2theA2levelA2ofA2thyroxineA2wouldA2increaseA2theA2secretionA2ofA2______
_.A2-A2Ans--bothA2TSHA2andA2TRH
AA2hypophysectomizedA2ratA2isA2missingA2itsA2_______.A2-A2Ans--pituitaryA2gland
ThyroxineA2isA2aA2_______.A2-A2Ans--slow-actingA2hormoneA2thatA2entersA2theA2nucleus
WhichA2ofA2theA2followingA2hormonesA2isA2regulatedA2byA2aA2positiveA2feedbackA2mechani
sm?A2-A2Ans--oxytocin
WhichA2ratA2hadA2theA2fastestA2basalA2metabolicA2rateA2(BMR)?A2-A2Ans--
TheA2normalA2ratA2hadA2theA2fastestA2BMR.
[ShowA2responseA2toA2predictA2questionA21]A2WhyA2didA2theA2metabolicA2ratesA2differA2bet
weenA2theA2normalA2ratA2andA2theA2surgicallyA2alteredA2rats?
A2HowA2wellA2didA2theA2resultsA2compareA2withA2yourA2prediction?A2-A2Ans--
TheA2metabolicA2rateA2wasA2fasterA2forA2theA2normalA2ratA2thanA2forA2theA2affectedA2rats.A2
((RememberA2toA2putA2whetherA2orA2notA2youA2predictedA2thisA2correctlyA2accordingA2toA2t
heA2questionsA2inA2theA2virtualA2lab!))
IfA2anA2animalA2hasA2beenA2thyroidectomized,A2whatA2hormone(s)A2wouldA2beA2missingA2i
nA2itsA2blood?A2-A2Ans--
CalcitoninA2andA2thyroxineA2wouldA2haveA2beenA2missingA2fromA2itsA2bloodA2ifA2itA2hadA2b
eenA2thyroidectomized.
, IfA2anA2animalA2hasA2beenA2hypophysectomized,A2whatA2effectA2wouldA2youA2expectA2toA2
seeA2inA2theA2hormoneA2levelsA2inA2itsA2body?A2-A2Ans--
ThisA2wouldA2meanA2theA2pituitaryA2glandA2wasA2removed,A2soA2theA2metabolicA2rateA2wo
uldA2goA2downA2becauseA2noA2THSA2wouldA2beA2produced.
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2normalA2rat'sA2BMR?A2-
A2Ans--TheA2metabolicA2rateA2increasedA2toA2higherA2thanA2theA2baselineA2amount.
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2thyroidectomizedA2rat'sA2BMR
?A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2thyroxineA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justright?
A2-A2Ans--
TheA2metabolicA2rateA2increasedA2butA2itA2stillA2wasA2notA2asA2highA2asA2theA2baseline.A2ItA
2comparesA2toA2theA2normalA2rat'sA2BMRA2becauseA2itA2wasA2stillA2ableA2toA2reachA2fairlyA2
normalA2ratesA2evenA2thoughA2itA2wasA2stillA2slightlyA2tooA2low.A2ThisA2meansA2thatA2theA2d
oseA2wasA2tooA2low.
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2hypophysectomizedA2rat'sA2B
MR?A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2thyroxineA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justright?
A2-A2Ans--
WhatA2wasA2theA2effectA2ofA2thyroxineA2injectionsA2onA2theA2hypophysectomizedA2rat'sA2B
MR?A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2thyroxineA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justright?
WhatA2wasA2theA2effectA2ofA2thyroid-
stimulatingA2hormoneA2(TSH)A2injectionsA2onA2theA2normalA2rat'sA2BMR?A2-A2Ans--
ItA2increasedA2theA2normalA2rat'sA2BMRA2pastA2theA2levelA2itA2wasA2atA2before.
WhatA2wasA2theA2effectA2ofA2TSHA2injectionsA2onA2theA2thyroidectomizedA2rat'sA2BMR?
A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WhyA2wasA2thisA2effectA2observed?A2-A2Ans--
ThereA2wasn'tA2anyA2effectA2becauseA2theA2TSHA2influencesA2theA2thyroidA2gland,A2butA2t
hisA2ratA2hadA2theA2thyroidA2glandA2removedA2soA2itA2couldn'tA2beA2stimulatedA2byA2theA2h
ormone.A2TheA2ratA2wasA2hypothyroidic.
WhatA2wasA2theA2effectA2ofA2TSHA2injectionsA2onA2theA2hypophysectomizedA2rat'sA2BMR?
A2HowA2doesA2theA2BMRA2inA2thisA2caseA2compareA2withA2theA2normalA2rat'sA2BMR?
A2WasA2theA2doseA2ofA2TSHA2inA2theA2syringeA2tooA2large,A2tooA2small,A2orA2justA2right?A2-
A2Ans--
TheA2BMRA2ofA2theA2hypophysectomizedA2ratA2increasedA2butA2itA2wasA2stillA2lowerA2thanA
2theA2BMRA2ofA2theA2normalA2rat.A2ThisA2meansA2thatA2theA2doseA2wasA2tooA2low.
WhatA2wasA2theA2effectA2ofA2propylthiouracilA2(PTU)A2injectionsA2onA2theA2normalA2rat'sA2B
MR?A2WhyA2didA2thisA2ratA2developA2aA2palpableA2goiter?A2-A2Ans--