NSG124 Unit 2 Chapter 6 Questions with Accurate
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Terms in this set (273)
What are cell wall They are used to kill susceptible bacteria by
synthesis inhibitors preventing the formation of strong, protective cell
primarily used for? walls.
What was the first Penicillin, which is a natural by-product of mold.
antibacterial drug
developed for general
use?
Name two types of drugs Cephalosporins and glycopeptide inhibitors (e.g.,
included in the cell wall vancomycin).
synthesis inhibitors class.
They bind to penicillin-binding proteins (PBPs),
How do cell wall synthesis
prevent mortar formation, or excessively activate
inhibitors work?
autolysins, leading to a leaky cell wall.
What is the role of PBPs maintain the alignment of glycopeptide bricks
penicillin-binding proteins and act as mortar to hold the wall together.
(PBPs) in bacterial cell
walls?
In which areas of the body Skin and mucous membranes, respiratory tract, ear,
are cell wall synthesis bone, and blood.
inhibitors most effective?
, List three common Strep throat, otitis media, and urinary tract infections.
infections treated with cell
wall synthesis inhibitors.
What are carbapenems They are used for severe infections such as sepsis and
and glycopeptide endocarditis.
inhibitors used for?
What defines drug Drug generations refer to the stages of development
generations in the context where later generations are modified to improve
of cell wall synthesis effectiveness or administration.
inhibitors?
How can the effectiveness By combining it with clavulanic acid to inhibit the
of penicillin be enhanced? bacterial enzyme lactamase.
What is the usual adult 500-1000 mg orally every 12 hours or 775 mg orally
dosage for amoxicillin? once daily (extended release).
What is the usual adult 1 g IV or IM every 6-8 hours.
dosage for cefazolin?
What are common side Nausea, vomiting, fever, chills, and pain at the
effects of cell wall injection site.
synthesis inhibitors?
What is 'Red man It is associated with the use of glycopeptide
syndrome' associated antibiotics like vancomycin, causing rash and redness.
with?
What adverse effect can Central nervous system changes, including confusion
carbapenems cause? and seizures.
Why are cell wall synthesis Because human cells do not have cell walls.
inhibitors less likely to
cause side effects in
humans?
What is the usual adult 20-35 mg/kg/dose IV loading dose, then 15-20
dosage for vancomycin? mg/kg/dose IV every 8-12 hours.
Answers | Latest Update
Save
Terms in this set (273)
What are cell wall They are used to kill susceptible bacteria by
synthesis inhibitors preventing the formation of strong, protective cell
primarily used for? walls.
What was the first Penicillin, which is a natural by-product of mold.
antibacterial drug
developed for general
use?
Name two types of drugs Cephalosporins and glycopeptide inhibitors (e.g.,
included in the cell wall vancomycin).
synthesis inhibitors class.
They bind to penicillin-binding proteins (PBPs),
How do cell wall synthesis
prevent mortar formation, or excessively activate
inhibitors work?
autolysins, leading to a leaky cell wall.
What is the role of PBPs maintain the alignment of glycopeptide bricks
penicillin-binding proteins and act as mortar to hold the wall together.
(PBPs) in bacterial cell
walls?
In which areas of the body Skin and mucous membranes, respiratory tract, ear,
are cell wall synthesis bone, and blood.
inhibitors most effective?
, List three common Strep throat, otitis media, and urinary tract infections.
infections treated with cell
wall synthesis inhibitors.
What are carbapenems They are used for severe infections such as sepsis and
and glycopeptide endocarditis.
inhibitors used for?
What defines drug Drug generations refer to the stages of development
generations in the context where later generations are modified to improve
of cell wall synthesis effectiveness or administration.
inhibitors?
How can the effectiveness By combining it with clavulanic acid to inhibit the
of penicillin be enhanced? bacterial enzyme lactamase.
What is the usual adult 500-1000 mg orally every 12 hours or 775 mg orally
dosage for amoxicillin? once daily (extended release).
What is the usual adult 1 g IV or IM every 6-8 hours.
dosage for cefazolin?
What are common side Nausea, vomiting, fever, chills, and pain at the
effects of cell wall injection site.
synthesis inhibitors?
What is 'Red man It is associated with the use of glycopeptide
syndrome' associated antibiotics like vancomycin, causing rash and redness.
with?
What adverse effect can Central nervous system changes, including confusion
carbapenems cause? and seizures.
Why are cell wall synthesis Because human cells do not have cell walls.
inhibitors less likely to
cause side effects in
humans?
What is the usual adult 20-35 mg/kg/dose IV loading dose, then 15-20
dosage for vancomycin? mg/kg/dose IV every 8-12 hours.
