NSG124 exam 1 -Questions with Complete Solutions
Half-life the time required for the amount of the drug in the body to decrease by 50%
therapeutic index ratio of toxic dose to therapeutic dose
Therapeutic response the intended (beneficial) effect of a drug
first pass effect The initial metabolism in the liver of a drug absorbed from the
gastrointestinal tract before the drug reaches systemic circulation through the bloodstream.
brand name name given to a drug by the pharmaceutical company that developed it;
also called a trade name or proprietary name
generic name legal noncommercial name for a drug
chemical name The name that describes the chemical composition and molecular
structure of a drug.
drug-drug interactions when one drug changes the way another drug affects the body
Drug-Food Interactions Food is known to increase, decrease, or delay drug absorption.
Food can bind with drugs, causing less or slower drug absorption.
Drug-herbal interactions occur when herbal or dietary supplements increase or decrease
a drugs effects
, Hepatotoxicity liver toxicity
Nephrotoxicity damage to the kidneys by a toxic substance
Malignant hyperthermia A hereditary condition of uncontrolled heat production that
occurs when susceptible people receive certain anesthetic drugs.
TREAT WITH Dantrolene!!
Inhibitor A substance that slows down or stops a chemical reaction
Antagonist a chemical or drug that binds to receptors in the brain and prevents an
agonist from having a reaction
Agonist a chemical that binds to a receptor and activates the receptor to produce a
biological response
Bioavailability A measure of the extent of drug absorption for a given drug and route
(from 0% to 100%).
Pharmacokinetics The process by which drugs are absorbed, distributed within the body,
metabolized, and excreted.
Pharmacodynamics The process by which a medication works on the body.
ADME Absorption, Distribution, Metabolism, Excretion/Elimination
Teratogenesis process involved in producing fetal deformities
Half-life the time required for the amount of the drug in the body to decrease by 50%
therapeutic index ratio of toxic dose to therapeutic dose
Therapeutic response the intended (beneficial) effect of a drug
first pass effect The initial metabolism in the liver of a drug absorbed from the
gastrointestinal tract before the drug reaches systemic circulation through the bloodstream.
brand name name given to a drug by the pharmaceutical company that developed it;
also called a trade name or proprietary name
generic name legal noncommercial name for a drug
chemical name The name that describes the chemical composition and molecular
structure of a drug.
drug-drug interactions when one drug changes the way another drug affects the body
Drug-Food Interactions Food is known to increase, decrease, or delay drug absorption.
Food can bind with drugs, causing less or slower drug absorption.
Drug-herbal interactions occur when herbal or dietary supplements increase or decrease
a drugs effects
, Hepatotoxicity liver toxicity
Nephrotoxicity damage to the kidneys by a toxic substance
Malignant hyperthermia A hereditary condition of uncontrolled heat production that
occurs when susceptible people receive certain anesthetic drugs.
TREAT WITH Dantrolene!!
Inhibitor A substance that slows down or stops a chemical reaction
Antagonist a chemical or drug that binds to receptors in the brain and prevents an
agonist from having a reaction
Agonist a chemical that binds to a receptor and activates the receptor to produce a
biological response
Bioavailability A measure of the extent of drug absorption for a given drug and route
(from 0% to 100%).
Pharmacokinetics The process by which drugs are absorbed, distributed within the body,
metabolized, and excreted.
Pharmacodynamics The process by which a medication works on the body.
ADME Absorption, Distribution, Metabolism, Excretion/Elimination
Teratogenesis process involved in producing fetal deformities
