Write your name here
Surname Other names
Pearson Edexcel Centre Number Candidate Number
International
Advanced Level
Biology
Advanced
Unit 4: The Natural Environment and Species
Survival
Tuesday 12 January 2016 – Afternoon Paper Reference
Time: 1 hour 30 minutes WBI04/01
You must have: Total Marks
Calculator
Instructions
• Use black ink or ball-point pen.
• centre
Fill in the boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• – there may
Answer the questions in the spaces provided
be more space than you need.
Information
• The total mark for this paper is 90.
• – use this asfora guide
The marks each question are shown in brackets
as to how much time to spend on each question.
• written communication will
Questions labelled with an asterisk (*) are ones where the quality of your
be assessed
– you should take particular care with your spelling, punctuation and grammar, as
well as the clarity of expression, on these questions.
Advice
• Keep
Read each question carefully before you start to answer it.
• Try toananswer
eye on the time.
• Check your answers
every question.
• if you have time at the end.
Turn over
P46934A
©2016 Pearson Education Ltd.
*P46934A0124*
1/1/3/1/
, Answer ALL questions.
Some questions must be answered with a cross in a box . If you change your mind about an
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
answer, put a line through the box and then mark your new answer with a cross .
1 Bacitracin is an antibiotic. It is one of a group of polypeptide antibiotics.
Bacitracin is affective against many types of bacteria, especially those that cause skin
infections.
(a) (i) Place a cross in the box next to the name of the monomer of a polypeptide.
(1)
A amino acid
B fatty acid
C glycerol
D nucleotide
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
(ii) Name the type of reaction that joins the monomers together in the formation
of a polypeptide.
(1)
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
(iii) Place a cross in the box next to the two parts of the monomers that are
joined together in this reaction.
(1)
A NH2 group and COOH group
B NH2 group and NH2 group
C NH2 group and OH group
D NH2 group and R group DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
2
*P46934A0224*
, (b) Antibiotics affect bacteria.
(i) Below are some statements about bacteria.
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
1 Bacteria are eukaryotic organisms
2 Bacteria contain ribosomes
3 Bacteria have cellulose cell walls
4 Bacteria contain DNA and RNA
Place a cross in the box next to the correct pair of statements about
bacteria.
(1)
A 1 and 2
B 1 and 3
C 2 and 4
D 3 and 4
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
(ii) Place a cross in the box next to the correct description of how antibiotics
work.
(1)
A antibiotics activate B cells
B antibiotics join several bacteria together
C antibiotics kill or prevent the growth of bacteria
D antibiotics stimulate phagocytosis by macrophages
(c) Suggest how bacitracin is given to a patient with a skin infection.
Give a reason for your answer.
(2)
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
3
*P46934A0324* Turn over
Surname Other names
Pearson Edexcel Centre Number Candidate Number
International
Advanced Level
Biology
Advanced
Unit 4: The Natural Environment and Species
Survival
Tuesday 12 January 2016 – Afternoon Paper Reference
Time: 1 hour 30 minutes WBI04/01
You must have: Total Marks
Calculator
Instructions
• Use black ink or ball-point pen.
• centre
Fill in the boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• – there may
Answer the questions in the spaces provided
be more space than you need.
Information
• The total mark for this paper is 90.
• – use this asfora guide
The marks each question are shown in brackets
as to how much time to spend on each question.
• written communication will
Questions labelled with an asterisk (*) are ones where the quality of your
be assessed
– you should take particular care with your spelling, punctuation and grammar, as
well as the clarity of expression, on these questions.
Advice
• Keep
Read each question carefully before you start to answer it.
• Try toananswer
eye on the time.
• Check your answers
every question.
• if you have time at the end.
Turn over
P46934A
©2016 Pearson Education Ltd.
*P46934A0124*
1/1/3/1/
, Answer ALL questions.
Some questions must be answered with a cross in a box . If you change your mind about an
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
answer, put a line through the box and then mark your new answer with a cross .
1 Bacitracin is an antibiotic. It is one of a group of polypeptide antibiotics.
Bacitracin is affective against many types of bacteria, especially those that cause skin
infections.
(a) (i) Place a cross in the box next to the name of the monomer of a polypeptide.
(1)
A amino acid
B fatty acid
C glycerol
D nucleotide
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
(ii) Name the type of reaction that joins the monomers together in the formation
of a polypeptide.
(1)
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
(iii) Place a cross in the box next to the two parts of the monomers that are
joined together in this reaction.
(1)
A NH2 group and COOH group
B NH2 group and NH2 group
C NH2 group and OH group
D NH2 group and R group DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
2
*P46934A0224*
, (b) Antibiotics affect bacteria.
(i) Below are some statements about bacteria.
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
1 Bacteria are eukaryotic organisms
2 Bacteria contain ribosomes
3 Bacteria have cellulose cell walls
4 Bacteria contain DNA and RNA
Place a cross in the box next to the correct pair of statements about
bacteria.
(1)
A 1 and 2
B 1 and 3
C 2 and 4
D 3 and 4
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
(ii) Place a cross in the box next to the correct description of how antibiotics
work.
(1)
A antibiotics activate B cells
B antibiotics join several bacteria together
C antibiotics kill or prevent the growth of bacteria
D antibiotics stimulate phagocytosis by macrophages
(c) Suggest how bacitracin is given to a patient with a skin infection.
Give a reason for your answer.
(2)
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
.. . .. . . .. . . .. . .. . . .. . . .. . .. . . .. . . . . . . . ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... .... ... ... ... ... ................... ..... ...... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... ..... ..... ..... ..... ..... .... ..... ..... ..... ..... ..... .. ... ..... ..... . .... ..... .............
3
*P46934A0324* Turn over
