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PCB 3063 EXAM 2 QUESTIONS AND VERIFIED ANSWERS

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PCB 3063 EXAM 2 QUESTIONS AND VERIFIED ANSWERS

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u-tube experiment


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Showed that cels need cell-to-cell contact in order to experience gene
transfer via conjugation. different strains were separated by a filter within a
u-shaped tube, making it so that the bacteria could physically touch one
another, but molecules or viruses could still go through. because no
growth occurred, it was concluded that physical contact was necessary for
genes to transfer.




haploinsufficient gene


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, when a single copy of a gene is not sufficient to enough gene product to
produce a wild-type phenotype.


ex. wing type in drosphilia;

1.) when females are heterozygous, they have noticed wings. when
homozygous, it is lethal, because it's phenotype makes it so that an
essential cell surface receptor is no longer encoded.




trisomy


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a type of aneuploidy in which there is a gain of a single chromosome (2n +
1)




how do you tell which strand is 5' to 3'?


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it will be given. otherwise, assume 5' is on the left, 3' on the right




positive-strand RNA


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Viral single-stranded RNA that can directly serve as mRNA to synthesize
proteins; it does not require a

,how are the genes and F-factor positioned among certain strains?


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the genes on the chromosomes are the same, but the position and
orientation of the F-factor differs among strains




gene distance and recombination rates


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the closer the 2 genes, the lower the frequency of recombination. if genes
are very far apart on the same chromosome, they can assort independently
[?]




pericentric inversion


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inversion that includes the centromere, which only changes the order of the
affected genes and does not cause its loss.




globin genes


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, group of genes genes that code for different globin polypeptides and may
have arisen from an ancestral gene




balanced translocation


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a translocation, such as a reciprocal translocation, in which the total amount
of genetic material is normal or nearly normal




reciprocal translocation


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an equal exchange of genetic material between two non-homologous
chromosomes, which are the most common type of translocation.
- they can create new links between genes that were previously unlinked
and affect those phenotypes.




linkage group


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Alleles of different genes that are located on the same chromosome and
tend to be inherited together

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