GNUR 294 FINAL EXAM- Pharmacotherapy of Alzheimers & Seizures | RATED 100%
GNUR 294 FINAL EXAM Pharmacotherapy of Alzheimer’s Disease • Builds up these plaques and deposited between the nerve cells • When between the nerve cells cannot transmit nerve signals • Develop mainly in the area in which you learn and retain new information • Long term memory can stay intact, but the ability to learn new information is affected • The nerve fibers and cells become tangled • Begins slowly, the patient is aware that they are losing memory • We know what causes it but don’t know why • Discovered in 2014 a way to identify the beta amyloid in the blood system by 2020 • Cannot cure alzheimer’s disease, can only slow it down • Ach deficiency also tend to see in movement disorders • Concerns: o Safety- losing the ability to perform ADLs, want to maintain the same caregiver, moving them out of their regular environment might make them worse • NMDA Receptor Blockers o Different formulations o Prevents glutamine from binding to cause from excitatory action o If too low can impair memory and cognition o Prevents the destruction of the neurons o Would not give to someone who is in renal failure o Cannot see plaques on a CT scan or an MRI o Once a day o Decrease in appetite, losing weight
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