GNUR 294 FINAL EXAM- Pharmacotherapy of Antivirals | RATED 100%
GNUR 294 FINAL EXAM Pharmacotherapy of Non-HIV Viral Infections • Viruses differ from bacteria in the sense they are compromised of a few molecules • Intracellular parasites, present in many places, some very lethal, some can co-exist • The issue with viruses that make them so difficult is because they used the host cell, they are very difficult to kill • Anti-viral drugs are the least effective • Mutate very rapidly, resistance develops because antiviral medication is geared towards forms of the virus and it changes so rapidly and the drug becomes ineffective • Image of what happens with a particular virus • Either to the target this point or kill off the viruses or boosting the patient’s own immune system • There is sometimes latent infections i.e. herpes • Nucleoside Analogs o When we look drugs to the fight the viruses o First cat. o Topical form- not as effective o Acutely ill i.e. immunocompromised – IV, very toxic, whenever a patient is receiving IV form slowly and hydrated o Does not kill or cure this virus completely o Short half lives- given multiple times during the day
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