Gnur 294 Exam 3(Verified)
Classification Prototype Routes, Onset, Duration of Action Mechanisms of Action Indications Contraindications Adverse Effects Pregnancy Drug Interactions Nursing Responsibilities • Thyroid Hormone Replacement • Synthetic T4 • Levoyhtroxine (Synthroid, Levothyroid, etc.) o Liothyronine (cytomel) o Liotrix (thyrolar) o Thyroid, desiccated (armour) • PO, IV (myxedema coma) • PO: slow onset • IV: 6-8 hrs • DOA: 1-3 weeks, half life 6-7 days • Identical to thyroid hormone: increasing metabolic rate (increasing O2 consumption, resps, and HR) • Increase rate of metabolism ? promotes growth and maturation • Primary and secondary hypothyroidism, or hypothyroid state resulting from surgical removal of thyroid gland, radiation, or congenital defect • Hypersensitivity • Thyrotoxicosis • Severe CV conditions, MI • Adrenal insufficiency
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