, CHAPTER 1
INTRODUCTION TO
BIOCHEMISTRY
1. A drug which prevents uric acid synthesis 8. Which are the cholesterol esters that enter
by inhibiting the enzyme xanthine cells through the receptor-mediated
oxidase is endocytosis of lipoproteins hydrolyzed?
(A) Aspirin (B) Allopurinol (A) Endoplasmin reticulum
(C) Colchicine (D) Probenecid (B) Lysosomes
(C) Plasma membrane receptor
2. Which of the following is required for
(D) Mitochondria
crystallization and storage of the
hormone insulin? 9. Which of the following phospholipids is
(A) localized to a greater extent in the outer
Mn++ (B) Mg++
leaflet of the membrane lipid bilayer?
(C) Ca++ (D) Zn++
(A) Choline phosphoglycerides
3. Oxidation of which substance in the body (B) Ethanolamine phosphoglycerides
yields the most calories (C) Inositol phosphoglycerides
(A) Glucose (B) Glycogen (D) Serine phosphoglycerides
(C) Protein (D) Lipids
10. All the following processes occur rapidly
4. Milk is deficient in which vitamins? in the membrane lipid bilayer except
(A) Vitamin C (B) Vitamin A (A) Flexing of fatty acyl chains
(C) Vitamin B2 (D) Vitamin K (B) Lateral diffusion of phospholipids
(C) Transbilayer diffusion of phopholipids
5. Milk is deficient of which mineral?
(D) Rotation of phospholipids around their long
(A) Phosphorus (B) Sodium axes
(C) Iron (D) Potassium
11. Which of the following statement is
6. Synthesis of prostaglandinsis is inhibited correct about membrane cholesterol?
by (A) The hydroxyl group is located near the centre
(A) Aspirin (B) Arsenic of the lipid layer
(C) Fluoride (D) Cyanide (B) Most of the cholesterol is in the form of a
cholesterol ester
7. HDL is synthesized and secreted from
(C) The steroid nucleus form forms a rigid, planar
(A) Pancreas (B) Liver structure
(C) Kidney (D) Muscle
,2 MCQs IN BIOCHEMISTRY
(D) The hydrocarbon chain of cholesterol projects (C) Dihydrolipoyl dehydrogenase
into the extracellular fluid (C) All of these
12. Which one is the heaviest particulate 21. The most active site of protein synthesis
component of the cell? is the
(A) Nucleus (B) Mitochondria (A) Nucleus (B) Ribosome
(C) Cytoplasm (D) Golgi apparatus (C) Mitochondrion (D) Cell sap
13. Which one is the largest particulate of the 22. The fatty acids can be transported into
cytoplasm? and out of mitochondria through
(A) Lysosomes (A) Active transport
(B) Mitochondria (B) Facilitated transfer
(C) Golgi apparatus (C) Non-facilitated transfer
(D) Entoplasmic reticulum (D) None of these
14. The degradative Processess are categorized 23. Mitochondrial DNA is
under the heading of
(A) Circular double stranded
(A) Anabolism (B) Catabolism (B) Circular single stranded
(C) Metabolism (D) None of the above (C) Linear double helix
15. The exchange of material takes place (D) None of these
(A) Only by diffusion 24. The absorption of intact protein from the
(B) Only by active transport gut in the foetal and newborn animals
(C) Only by pinocytosis takes place by
(D) All of these (A) Pinocytosis (B) Passive diffusion
(C) Simple diffusion (D) Active transport
16. The average pH of Urine is
(A) 7.0 (B) 6.0 25. The cellular organelles called “suicide
bags” are
(C) 8.0 (D) 0.0
(A) Lysosomes (B) Ribosomes
17. The pH of blood is 7.4 when the ratio (C) Nucleolus (D) Golgi’s bodies
between H2CO3 and NaHCO3 is
(A) 1 : 10 (B) 1 : 20 26. From the biological viewpoint, solutions
can be grouped into
(C) 1 : 25 (C) 1 : 30
(A) Isotonic solution
18. The phenomenon of osmosis is opposite (B) Hypotonic solutions
to that of
(C) Hypertonic solution
(A) Diffusion (B) Effusion (D) All of these
(C) Affusion (D) Coagulation
27. Bulk transport across cell membrane is
19. The surface tension in intestinal lumen accomplished by
between fat droplets and aqueous
(A) Phagocytosis (B) Pinocytosis
medium is decreased by
(C) Extrusion (D) All of these
(A) Bile Salts (B) Bile acids
(C) Conc. H2SO4 (D) Acetic acid 28. The ability of the cell membrane to act as
a selective barrier depends upon
20. Which of the following is located in the
(A) The lipid composition of the membrane
mitochondria?
(B) The pores which allows small molecules
(A) Cytochrome oxidase
(C) The special mediated transport systems
(B) Succinate dehydrogenase
(D) All of these
, INTRODUCTION TO BIOCHEMISTRY 3
29. Carrier protein can 35. Enzymes catalyzing electron transport
(A) Transport only one substance are present mainly in the
(B) Transport more than one substance (A) Ribosomes
(C) Exchange one substance to another (B) Endoplasmic reticulum
(D) Perform all of these functions (C) Lysosomes
(D) Inner mitochondrial membrane
30. A lipid bilayer is permeable to
(A) Urea (B) Fructose 36. Mature erythrocytes do not contain
(C) Glucose (D) Potassium (A) Glycolytic enzymes(B) HMP shunt enzymes
(C) Pyridine nucleotide(D) ATP
31. The Golgi complex
(A) Synthesizes proteins 37. In mammalian cells rRNA is produced
mainly in the
(B) Produces ATP
(C) Provides a pathway for transporting chemicals (A) Endoplasmic reticulum
(D) Forms glycoproteins (B) Ribosome
(C) Nucleolus
32. The following points about microfilaments
(D) Nucleus
are true except
(A) They form cytoskeleton with microtubules 38. Genetic information of nuclear DNA is
transmitted to the site of protein synthesis
(B) They provide support and shape
by
(C) They form intracellular conducting channels
(A) rRNA (B) mRNA
(D) They are involved in muscle cell contraction
(C) tRNA (D) Polysomes
33. The following substances are cell
inclusions except 39. The power house of the cell is
(A) Melanin (B) Glycogen (A) Nucleus (B) Cell membrane
(C) Lipids (D) Centrosome (C) Mitochondria (D) Lysosomes
34. Fatty acids can be transported into and 40. The digestive enzymes of cellular
out of cell membrane by compounds are confined to
(A) Active transport (B) Facilitated transport (A) Lysosomes (B) Ribosomes
(C) Diffusion (D) Osmosis (C) Peroxisomes (D) Polysomes
ANSWERS
1. B 2. D 3. D 4. A 5. C 6. A
7. B 8. B 9. A 10. C 11. C 12. A
13. B 14. B 15. D 16. B 17. B 18. A
19. A 20. D 21. B 22. B 23. A 24. A
25. A 26. D 27. D 28. D 29. D 30. A
31. D 32. C 33. D 34. B 35. D 36. C
37. C 38. D 39. C 40. A
INTRODUCTION TO
BIOCHEMISTRY
1. A drug which prevents uric acid synthesis 8. Which are the cholesterol esters that enter
by inhibiting the enzyme xanthine cells through the receptor-mediated
oxidase is endocytosis of lipoproteins hydrolyzed?
(A) Aspirin (B) Allopurinol (A) Endoplasmin reticulum
(C) Colchicine (D) Probenecid (B) Lysosomes
(C) Plasma membrane receptor
2. Which of the following is required for
(D) Mitochondria
crystallization and storage of the
hormone insulin? 9. Which of the following phospholipids is
(A) localized to a greater extent in the outer
Mn++ (B) Mg++
leaflet of the membrane lipid bilayer?
(C) Ca++ (D) Zn++
(A) Choline phosphoglycerides
3. Oxidation of which substance in the body (B) Ethanolamine phosphoglycerides
yields the most calories (C) Inositol phosphoglycerides
(A) Glucose (B) Glycogen (D) Serine phosphoglycerides
(C) Protein (D) Lipids
10. All the following processes occur rapidly
4. Milk is deficient in which vitamins? in the membrane lipid bilayer except
(A) Vitamin C (B) Vitamin A (A) Flexing of fatty acyl chains
(C) Vitamin B2 (D) Vitamin K (B) Lateral diffusion of phospholipids
(C) Transbilayer diffusion of phopholipids
5. Milk is deficient of which mineral?
(D) Rotation of phospholipids around their long
(A) Phosphorus (B) Sodium axes
(C) Iron (D) Potassium
11. Which of the following statement is
6. Synthesis of prostaglandinsis is inhibited correct about membrane cholesterol?
by (A) The hydroxyl group is located near the centre
(A) Aspirin (B) Arsenic of the lipid layer
(C) Fluoride (D) Cyanide (B) Most of the cholesterol is in the form of a
cholesterol ester
7. HDL is synthesized and secreted from
(C) The steroid nucleus form forms a rigid, planar
(A) Pancreas (B) Liver structure
(C) Kidney (D) Muscle
,2 MCQs IN BIOCHEMISTRY
(D) The hydrocarbon chain of cholesterol projects (C) Dihydrolipoyl dehydrogenase
into the extracellular fluid (C) All of these
12. Which one is the heaviest particulate 21. The most active site of protein synthesis
component of the cell? is the
(A) Nucleus (B) Mitochondria (A) Nucleus (B) Ribosome
(C) Cytoplasm (D) Golgi apparatus (C) Mitochondrion (D) Cell sap
13. Which one is the largest particulate of the 22. The fatty acids can be transported into
cytoplasm? and out of mitochondria through
(A) Lysosomes (A) Active transport
(B) Mitochondria (B) Facilitated transfer
(C) Golgi apparatus (C) Non-facilitated transfer
(D) Entoplasmic reticulum (D) None of these
14. The degradative Processess are categorized 23. Mitochondrial DNA is
under the heading of
(A) Circular double stranded
(A) Anabolism (B) Catabolism (B) Circular single stranded
(C) Metabolism (D) None of the above (C) Linear double helix
15. The exchange of material takes place (D) None of these
(A) Only by diffusion 24. The absorption of intact protein from the
(B) Only by active transport gut in the foetal and newborn animals
(C) Only by pinocytosis takes place by
(D) All of these (A) Pinocytosis (B) Passive diffusion
(C) Simple diffusion (D) Active transport
16. The average pH of Urine is
(A) 7.0 (B) 6.0 25. The cellular organelles called “suicide
bags” are
(C) 8.0 (D) 0.0
(A) Lysosomes (B) Ribosomes
17. The pH of blood is 7.4 when the ratio (C) Nucleolus (D) Golgi’s bodies
between H2CO3 and NaHCO3 is
(A) 1 : 10 (B) 1 : 20 26. From the biological viewpoint, solutions
can be grouped into
(C) 1 : 25 (C) 1 : 30
(A) Isotonic solution
18. The phenomenon of osmosis is opposite (B) Hypotonic solutions
to that of
(C) Hypertonic solution
(A) Diffusion (B) Effusion (D) All of these
(C) Affusion (D) Coagulation
27. Bulk transport across cell membrane is
19. The surface tension in intestinal lumen accomplished by
between fat droplets and aqueous
(A) Phagocytosis (B) Pinocytosis
medium is decreased by
(C) Extrusion (D) All of these
(A) Bile Salts (B) Bile acids
(C) Conc. H2SO4 (D) Acetic acid 28. The ability of the cell membrane to act as
a selective barrier depends upon
20. Which of the following is located in the
(A) The lipid composition of the membrane
mitochondria?
(B) The pores which allows small molecules
(A) Cytochrome oxidase
(C) The special mediated transport systems
(B) Succinate dehydrogenase
(D) All of these
, INTRODUCTION TO BIOCHEMISTRY 3
29. Carrier protein can 35. Enzymes catalyzing electron transport
(A) Transport only one substance are present mainly in the
(B) Transport more than one substance (A) Ribosomes
(C) Exchange one substance to another (B) Endoplasmic reticulum
(D) Perform all of these functions (C) Lysosomes
(D) Inner mitochondrial membrane
30. A lipid bilayer is permeable to
(A) Urea (B) Fructose 36. Mature erythrocytes do not contain
(C) Glucose (D) Potassium (A) Glycolytic enzymes(B) HMP shunt enzymes
(C) Pyridine nucleotide(D) ATP
31. The Golgi complex
(A) Synthesizes proteins 37. In mammalian cells rRNA is produced
mainly in the
(B) Produces ATP
(C) Provides a pathway for transporting chemicals (A) Endoplasmic reticulum
(D) Forms glycoproteins (B) Ribosome
(C) Nucleolus
32. The following points about microfilaments
(D) Nucleus
are true except
(A) They form cytoskeleton with microtubules 38. Genetic information of nuclear DNA is
transmitted to the site of protein synthesis
(B) They provide support and shape
by
(C) They form intracellular conducting channels
(A) rRNA (B) mRNA
(D) They are involved in muscle cell contraction
(C) tRNA (D) Polysomes
33. The following substances are cell
inclusions except 39. The power house of the cell is
(A) Melanin (B) Glycogen (A) Nucleus (B) Cell membrane
(C) Lipids (D) Centrosome (C) Mitochondria (D) Lysosomes
34. Fatty acids can be transported into and 40. The digestive enzymes of cellular
out of cell membrane by compounds are confined to
(A) Active transport (B) Facilitated transport (A) Lysosomes (B) Ribosomes
(C) Diffusion (D) Osmosis (C) Peroxisomes (D) Polysomes
ANSWERS
1. B 2. D 3. D 4. A 5. C 6. A
7. B 8. B 9. A 10. C 11. C 12. A
13. B 14. B 15. D 16. B 17. B 18. A
19. A 20. D 21. B 22. B 23. A 24. A
25. A 26. D 27. D 28. D 29. D 30. A
31. D 32. C 33. D 34. B 35. D 36. C
37. C 38. D 39. C 40. A
