GNUR 294 EXAM 2 REVIEW(STUDY GUIDE) | RATED 100%

GNUR 294 EXAM 2 REVIEW (M7-13) MODULE 7 Pharmacotherapy during Pregnancy Quick facts: Teras = Greek word meaning “monster” Teratogenesis = “to produce a monster” Teratogens – adverse affects in pregnancy • Effects structural formation in fetal tissue • Effects organ function in fetal tissue • Causes fetal demise 2 individuals of concern: 1) Pregnant women 2) Fetus Fetal-placental barrier – not effective, many drug molecules can cross and cause harm to fetus Adverse effects in pregnant women – causes harm to fetus • Ex: on antihypertensive, dose was too large ? BP ? dramatically ? ? tissue perfusion ? fetus experiences same effects Stages of Fetal Development 3 stages: 1) Preimplantation period – 1-2 weeks of pregnancy before implantation, “all or none” period, women don’t know they are pregnant at this time • Exposure to teratogen at this stage: o Death o No effect at all 2) Embryonic period – 3-8 weeks, point of maximum sensitivity, all structures are being developed • Exposure to teratogen at this stage: o Structural abnormalities 3) Fetal period - 9-40 weeks or until birth • Exposure to teratogen at this stage: o Effects organ functions