ABSITE Questions Questions and Correct
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2 weeks after a whipple operation, your patient continues to have
early satiety with oral intake. You decide to start metoglopramide
(Reglan) and erythromycin. What receptor does erythromycin bind to
increase gastrointestinal motility?
Ans: Motilin (found primarily in the stomach, duodenum, and
colon)
Proteins are synthesized from:
a. mRNA
b. tRNA
c. dsDNA
d. ssDNA
Ans: mRNA
1 week after an APR, our patient develops urosepsis requiring volume
resuscitation, antibiotics, and moderate amounts of levophed and
vasopressin. E. coli grows out from the blood cultures. What portion of
the lipopolysaccharide complex accounts for its toxicity
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Ans: Lipid A (with gram negative sepsis; stimulator of TNFα)
Steroid hormones:
a. Bind a receptor on the plasma membrane and activate a plasma
membrane enzyme
b. Bind a cytoplasmic receptor, enter the nucleus, and affect
transcription of proteins
c. Bind a receptor in the nucleus and affect transcription of proteins
d. Do not enter the cell
Ans: (b)
Bind a receptor in the cell cytoplasm, enter the nucleus as a
steroid-receptor complex, and affect transcription of proteins
4 days after an Ivor-Lewis esophagectomy, you decide to start enteral
tube feeding through a J-tube. The long chain fatty acids contained in
the tube feeds:
a. Enter the circulation via the portal system
b. Enter the circulation via lymphatics
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c. Are only synthesized in the body
d. Are not found in chylomicrons
Ans: (b)
Long-chain FAs enter the body through terminal lacteals
(absorption through the lymphatic system) either as free LCFAs
or as chylomicrons
Medium- and short-chain FAs along with proteins/CHO enter
through the portal circulation
Cells divide during what phase of the cell cycle?
a. G1
b. S
c. G2
d. M
Ans: (d)
Cells divide during the M phase (most radiosensitive)
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Cell cycle length is determined by what phase of the cell cycle?
a. G1
b. S
c. G2
d. M
Ans: (a)
G1 ↔ G0 phase determines cell cycle length (most variable cell
period)
Most RNA/protein synthesis
Of the following, which is the most critical component in the
neovascularization of tumor metastases?
a. HER receptor
b. VEGF receptor
c. Neu receptor
d. FGF receptor
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