Chemotherapy Certification Exam
Questions and Answers Graded A+
Doxorubicin - Correct answer-Cardiotoxic
TISSUE VESICANT
Baseline MUGA and total dose (CONCERN at 550 mg/m2)
URINE=RED
IF EXTRAVASATION OCCURS= cool/ice + Totect
Idamycin - Correct answer-Cardiotoxic (cardiomyopathy)
Bleomycin - Correct answer-AVOID oxygen supplementation
Methotrexate - Correct answer-*Leukovorin decreases cytotoxicity*
Pemetrexed - Correct answer-Vitamin B12 & folic acid supplements to decrease
toxicity
Fludarabine - Correct answer-Immunosuppression
Thioguanine - Correct answer-Bone Marrow Suppression
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, Stomatitis/Mucositis
5-FU - Correct answer-*Stomatitis
Bone marrow depression
*Diarrhea
Mucositis
Capeticibine - Correct answer-***Pro-drug that converts 5FU in liver
Stomatitis & mucositis
Palmar-plantar erythrodysthesias (hand foot syndrome)
Cytarabine or Cytosine Arabinoside - Correct answer-Cerebellar neurotoxicity
Gemcitabine - Correct answer-Radiosensitizer DO NOT GIVE W/ RADIATION,
except at very low doses
Carmustine - Correct answer-***Solvent is alcohol
Alcohol sensivity is an issue
Mix ONLY in 0.9% NaCl
Carboplatin - Correct answer-Dose by CALVERT formula
Allergic reaction increased from 1-27% in pts receiving >6-7 courses
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2
Questions and Answers Graded A+
Doxorubicin - Correct answer-Cardiotoxic
TISSUE VESICANT
Baseline MUGA and total dose (CONCERN at 550 mg/m2)
URINE=RED
IF EXTRAVASATION OCCURS= cool/ice + Totect
Idamycin - Correct answer-Cardiotoxic (cardiomyopathy)
Bleomycin - Correct answer-AVOID oxygen supplementation
Methotrexate - Correct answer-*Leukovorin decreases cytotoxicity*
Pemetrexed - Correct answer-Vitamin B12 & folic acid supplements to decrease
toxicity
Fludarabine - Correct answer-Immunosuppression
Thioguanine - Correct answer-Bone Marrow Suppression
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
, Stomatitis/Mucositis
5-FU - Correct answer-*Stomatitis
Bone marrow depression
*Diarrhea
Mucositis
Capeticibine - Correct answer-***Pro-drug that converts 5FU in liver
Stomatitis & mucositis
Palmar-plantar erythrodysthesias (hand foot syndrome)
Cytarabine or Cytosine Arabinoside - Correct answer-Cerebellar neurotoxicity
Gemcitabine - Correct answer-Radiosensitizer DO NOT GIVE W/ RADIATION,
except at very low doses
Carmustine - Correct answer-***Solvent is alcohol
Alcohol sensivity is an issue
Mix ONLY in 0.9% NaCl
Carboplatin - Correct answer-Dose by CALVERT formula
Allergic reaction increased from 1-27% in pts receiving >6-7 courses
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2