Chemotherapy Biotherapy Certification
Exam Questions and Answers Exam A+
Resources - Correct answer-nccn.org
cancer.org
LESSON 1: Cell cycle - Correct answer-g1- increase in size
s- dna replicated
g2- cell enlarge and ready to divide
m phase- 2 hours
mitosis - Correct answer-4 stages, prophase, metaphase, anaphase, telophase
-chemo targets certain points in the process
apoptosis - Correct answer-programmed cell death
hematopoiesis - Correct answer-formation of blood cells & how cells differentiate
-myeloid: pre cells mature into RBCs, platelets and WBCs
-lymphoid: pre cells- mature into WBCS
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,Principles of Biotherapy: p51-95 immunology - Correct answer--defense against
foreign organisms, homeostasis (destroy aged cells), surveillance
immune responses - Correct answer-innate: primary line of defense, non specific,
no memory
adaptive: secondary line of defence with specific memry
cytokines - Correct answer--effect growth and differentiation of WBC
-interferons, tumor necrosis factors, growth factos and interleukins
-small protein molecules released by cells throughout body providing
comunication between cells of the immune system
-regular antiboddy production and function of b cells
vaccines for cancer prevention - Correct answer--hep B prevents hepatitis and
hepatocellular carcinoma
-hpv vaccine
filgrastim aka neupogen - Correct answer-SC or IV to derease infection in patients
with neutropenic fever associated with myelosuppressive anticancer treatments for
nonmyeloid malignancies
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,tbo-filgramstim/ pegfilgrastim - Correct answer-reduce duration of neutroenia in
patients with non myeloid malignancies
palifermin - Correct answer-IV to dec incidence of oral mucositis in patients with
hem malignanies before BMT
sargramostim - Correct answer-aka leukine - patients with AML following chemo
to shorten neutrophil recovery and reduce incidence of infection
IFN gamma - Correct answer-reduce frequency and severity o infections related to
granulomatous disease
aldeleukin - Correct answer-treat renal cell carcinoma and metastatic melanoma
oprevelkin - Correct answer-prevent severe thrombocytopenia and refuce need for
platelet transfusions in patients with nonmyeloid malig
plerixafor - Correct answer-with filgrastim to mobilize hematopoeitc stem cells for
collection from peripheral blood of patients
sipuleucel - Correct answer-castrate resistant prostate cancer
rituximab - Correct answer-rituxan- treatment of relapsed or refractory low grade
follicular b cell NHL_ first line traetment in combo with chemo in patients with
response
-can treat severe rheumatoid arthritis
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, -can have severe reactions (hypotension, urticaria, angiodema, hypoxia, rigors,
dyspnea, chills, fever, nausea, rash, renal tox)
-premed with tylenol and benadryl
-slow infusion to resolve some side effects, side effects reduce with each infusion
immune system - Correct answer-1st line: skin , ucous membrane, gut flora
second line: phagocytes:
3rd line antibodies, t and b cells
malignant tumor (cancer) - Correct answer-cell strcuture different from parent
tissue, cell division uncontrolled, loosely adherent, invade neighboring tissue,
establish blood vessels
Approaches to treatment - Correct answer-cure: prolonged absence of disease
control: no further growth
and palliation : comfort
neoadjuvant - Correct answer-therapy in the first step to shrink a tumor before the
main treatment) surgery is given
-chemo, radiation, hormone therapy
©COPYRIGHT 2025, ALL RIGHTS RESERVED 4
Exam Questions and Answers Exam A+
Resources - Correct answer-nccn.org
cancer.org
LESSON 1: Cell cycle - Correct answer-g1- increase in size
s- dna replicated
g2- cell enlarge and ready to divide
m phase- 2 hours
mitosis - Correct answer-4 stages, prophase, metaphase, anaphase, telophase
-chemo targets certain points in the process
apoptosis - Correct answer-programmed cell death
hematopoiesis - Correct answer-formation of blood cells & how cells differentiate
-myeloid: pre cells mature into RBCs, platelets and WBCs
-lymphoid: pre cells- mature into WBCS
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
,Principles of Biotherapy: p51-95 immunology - Correct answer--defense against
foreign organisms, homeostasis (destroy aged cells), surveillance
immune responses - Correct answer-innate: primary line of defense, non specific,
no memory
adaptive: secondary line of defence with specific memry
cytokines - Correct answer--effect growth and differentiation of WBC
-interferons, tumor necrosis factors, growth factos and interleukins
-small protein molecules released by cells throughout body providing
comunication between cells of the immune system
-regular antiboddy production and function of b cells
vaccines for cancer prevention - Correct answer--hep B prevents hepatitis and
hepatocellular carcinoma
-hpv vaccine
filgrastim aka neupogen - Correct answer-SC or IV to derease infection in patients
with neutropenic fever associated with myelosuppressive anticancer treatments for
nonmyeloid malignancies
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2
,tbo-filgramstim/ pegfilgrastim - Correct answer-reduce duration of neutroenia in
patients with non myeloid malignancies
palifermin - Correct answer-IV to dec incidence of oral mucositis in patients with
hem malignanies before BMT
sargramostim - Correct answer-aka leukine - patients with AML following chemo
to shorten neutrophil recovery and reduce incidence of infection
IFN gamma - Correct answer-reduce frequency and severity o infections related to
granulomatous disease
aldeleukin - Correct answer-treat renal cell carcinoma and metastatic melanoma
oprevelkin - Correct answer-prevent severe thrombocytopenia and refuce need for
platelet transfusions in patients with nonmyeloid malig
plerixafor - Correct answer-with filgrastim to mobilize hematopoeitc stem cells for
collection from peripheral blood of patients
sipuleucel - Correct answer-castrate resistant prostate cancer
rituximab - Correct answer-rituxan- treatment of relapsed or refractory low grade
follicular b cell NHL_ first line traetment in combo with chemo in patients with
response
-can treat severe rheumatoid arthritis
©COPYRIGHT 2025, ALL RIGHTS RESERVED 3
, -can have severe reactions (hypotension, urticaria, angiodema, hypoxia, rigors,
dyspnea, chills, fever, nausea, rash, renal tox)
-premed with tylenol and benadryl
-slow infusion to resolve some side effects, side effects reduce with each infusion
immune system - Correct answer-1st line: skin , ucous membrane, gut flora
second line: phagocytes:
3rd line antibodies, t and b cells
malignant tumor (cancer) - Correct answer-cell strcuture different from parent
tissue, cell division uncontrolled, loosely adherent, invade neighboring tissue,
establish blood vessels
Approaches to treatment - Correct answer-cure: prolonged absence of disease
control: no further growth
and palliation : comfort
neoadjuvant - Correct answer-therapy in the first step to shrink a tumor before the
main treatment) surgery is given
-chemo, radiation, hormone therapy
©COPYRIGHT 2025, ALL RIGHTS RESERVED 4
