Pharmacology Final Exam - Multiple
Choice Questions With Correct
Answers Latest Update 2025/2026
GRADED A+
The bactericidal antibiotic that interferes with bacterial cell-wall synthesis and that may
cause "red man syndrome" if injected too rapidly is
A. piperacillin
B. vancomycin
C. gentamicin
D. clindamycin
E. cephalexin - correct answerB. vancomycin
The main pharmacokinetic feature of aminoglycosides is that they are
A. lipid soluble
B. well absorbed orally
C. poorly absorbed from the GI tract and excreted mostly unchanged in the urine if
injected
D. devoid of serious adverse effects
E. undergo extensive metabolism - correct answerC. poorly absorbed from the GI tract
and excreted mostly unchanged in the urine if injected
Which of the following is NOT correct about antifungal drugs or fungal infection?
A. systemic infection may occur in patients who are receiving drugs to suppress their
immune system
B. warts are an example of a dermatophytic fungal infection
C. the majority of antifungal drugs interfere with fungal cell-wall integrity
D. amphotericin B is associated with serious renal toxicity
E. topical antifungal drugs are available OTC - correct answerB. warts are an example
of a dermatophytic fungal infection
Which antifungal drug is matched with its correct mechanism of action?
A. echinocandins inhibit polysaccharide (glucan) synthesis in the cell wall
B. flucytosine binds to the cell membrane
C. ticonazole is an antimetabolite for fungal RNA
D. amphotericin B binds to a cytochrome P450-dependent enzyme
E. ketoconazole inhibits proteases in the host cell nuclei - correct answerA.
echinocandins inhibit polysaccharide (glucan) synthesis in the cell wall
,Which of the following is correct about viruses?
A. active infection is the only way to develop immunity to the microorganism
B. viruses attach to the keratin protein and remain dormant for years
C. viruses can quickly develop resistance to drugs
D. viruses die as soon as they land on hard surfaces
E. respiratory viral infections are treated with acyclovir - correct answerC. viruses can
quickly develop resistance to drugs
Which drug is effective against systemic viral infections?
A. griseofulvin
B. butenafine
C. gentian violet
D. clotrimazole
E. enfuvirtide - correct answerE. enfuvirtide
the mechanisms of action for antiviral medications include
A. changing cell-wall synthesis
B. binding to ergosterol
C. inhibiting cell mitosis
D. inhibiting neuraminidase
E. facilitating viral fusion to the host cell - correct answerD. inhibiting neuraminidase
Which of the following is NOT true of the treatment for viral infections?
A. they are difficult to treat due to host cell invasion
B. immunity can be gained through the attenuated live virus
C. treatment can be given via an intranasal spray
D. the vaccines are contraindicated in people allergic to eggs
E. effective treatment occurs only with respiratory drug administration - correct
answerE. effective treatment occurs only with respiratory drug administration
The antimetabolite that blocks DNA synthesis by interfering with folic acid is
A. mercaptopurine
B. fluorouracil
C. methotrexate
D. cytarabine
E. tamoxifen - correct answerC. methotrexate
The drug that binds to mitotic tubules to cause metaphase arrest is
A. doxorubicin
B. asparaginase
C. etoposide
D. vincristine
E. mercaptopurine - correct answerD. vincristine
The monoclonal antibody that inhibits vascular endothelial growth factor (VEGF) and
new blood vessel formation is
,A. imatinib
B. trastuzumab
C. bevacizumab
D. gefitinib
E. cetuximab - correct answerC. bevacizumab
Which of the following is true of chemotherapy?
A. one of the early goals of chemotherapy is remission
B. antineoplastic drugs only attack cancerous cells
C. drug resistance is increased with combination therapy
D. it is the primary form of treatment for solid tumors
E. it is usually effective after one treatment - correct answerA. one of the early goals of
chemotherapy is remission
Select the correct statements for alkylating drugs.
A. bind irreversibly with nucleic acids
B. decrease cells' ability to synthesize proteins
C. are cell-cycle nonspecific
D. bind irreversibly with nucleic acids
E. all statements are true - correct answerE. all statements are true
The mechanisms of actions for the antimetabolites include
A. preventing DNA replication
B. blocking DNA synthesis
C. forming abnormal nucleotides
D. preventing DNA replication and forming abnormal nucleotides
E. all of these - correct answerE. all of these
Select the correct statements about the plant extract treatments for cancer.
A. they can bind to microtubules
B. they induce enzymes
C. they increase DNA strand breakage
D. they can bind to microtubules, and they increase DNA strand breakage
E. all statements are true - correct answerD. they can bind to microtubules, and they
increase DNA strand breakage
Barbiturate and benzodiazepine hypnotics both
A. increase NREM stage 2 sleep
B. increase REM sleep
C. increase NREM stage 4 sleep
D. cause REM rebound
E. all of these statements are true - correct answerA. increase NREM stage 2 sleep
Disadvantages to the use of barbiturate hypnotics include
A. development of drug tolerance
B. risk of drug dependency
, C. disruption of normal stages of sleep
D. suppression of REM sleep
E. all of these statements are true - correct answerE. all of these statements are true
The correct statement concerning the use of hypnotic drugs is A. zolpidem binds to the
GABA receptor
B. benzodiazepines increase chloride channel opening
C. barbiturates block the GABA receptor
D. ramelteon is a melatonin antagonist
E. flumazenil is a benzodiazepine receptor agonist - correct answerB. benzodiazepines
increase chloride channel opening
Flurazepam
A. is classified as long-acting
B. forms active metabolites
C. may cause next-day residual effects
D. increases chloride ion influx
E. all of these statements are true - correct answerE. all of these statements are true
Eszopiclone
A. is classified as a benzodiazepine
B. has a half-life of 1-2 hours
C. increases total sleep time
D. is used as an antianxiety agent
E. is also used as an anticonvulsant - correct answerC. increases total sleep time
Zolpidem
A. binds to the alpha-1 subunit of the GABA A receptor
B. is useful as a muscle relaxant
C. has a slow onset of action
D. is useful as an anticonvulsant
E. is chemically classified as a benzodiazepine - correct answerA. binds to the alpha-1
subunit of the GABA A receptor
Alcohol has pharmacological effects on which body systems? A. central nervous system
B. gastrointestinal system
C. renal system
D. vascular system
E. all of these - correct answerE. all of these
The main pharmacologic effect of the SSRIs is
A. increase levels of norepinephrine
B. increase levels of serotonin
C. decrease levels of norepinephrine
D. decrease levels of serotonin
E. decrease levels of dopamine - correct answerB. increase levels of serotonin
Choice Questions With Correct
Answers Latest Update 2025/2026
GRADED A+
The bactericidal antibiotic that interferes with bacterial cell-wall synthesis and that may
cause "red man syndrome" if injected too rapidly is
A. piperacillin
B. vancomycin
C. gentamicin
D. clindamycin
E. cephalexin - correct answerB. vancomycin
The main pharmacokinetic feature of aminoglycosides is that they are
A. lipid soluble
B. well absorbed orally
C. poorly absorbed from the GI tract and excreted mostly unchanged in the urine if
injected
D. devoid of serious adverse effects
E. undergo extensive metabolism - correct answerC. poorly absorbed from the GI tract
and excreted mostly unchanged in the urine if injected
Which of the following is NOT correct about antifungal drugs or fungal infection?
A. systemic infection may occur in patients who are receiving drugs to suppress their
immune system
B. warts are an example of a dermatophytic fungal infection
C. the majority of antifungal drugs interfere with fungal cell-wall integrity
D. amphotericin B is associated with serious renal toxicity
E. topical antifungal drugs are available OTC - correct answerB. warts are an example
of a dermatophytic fungal infection
Which antifungal drug is matched with its correct mechanism of action?
A. echinocandins inhibit polysaccharide (glucan) synthesis in the cell wall
B. flucytosine binds to the cell membrane
C. ticonazole is an antimetabolite for fungal RNA
D. amphotericin B binds to a cytochrome P450-dependent enzyme
E. ketoconazole inhibits proteases in the host cell nuclei - correct answerA.
echinocandins inhibit polysaccharide (glucan) synthesis in the cell wall
,Which of the following is correct about viruses?
A. active infection is the only way to develop immunity to the microorganism
B. viruses attach to the keratin protein and remain dormant for years
C. viruses can quickly develop resistance to drugs
D. viruses die as soon as they land on hard surfaces
E. respiratory viral infections are treated with acyclovir - correct answerC. viruses can
quickly develop resistance to drugs
Which drug is effective against systemic viral infections?
A. griseofulvin
B. butenafine
C. gentian violet
D. clotrimazole
E. enfuvirtide - correct answerE. enfuvirtide
the mechanisms of action for antiviral medications include
A. changing cell-wall synthesis
B. binding to ergosterol
C. inhibiting cell mitosis
D. inhibiting neuraminidase
E. facilitating viral fusion to the host cell - correct answerD. inhibiting neuraminidase
Which of the following is NOT true of the treatment for viral infections?
A. they are difficult to treat due to host cell invasion
B. immunity can be gained through the attenuated live virus
C. treatment can be given via an intranasal spray
D. the vaccines are contraindicated in people allergic to eggs
E. effective treatment occurs only with respiratory drug administration - correct
answerE. effective treatment occurs only with respiratory drug administration
The antimetabolite that blocks DNA synthesis by interfering with folic acid is
A. mercaptopurine
B. fluorouracil
C. methotrexate
D. cytarabine
E. tamoxifen - correct answerC. methotrexate
The drug that binds to mitotic tubules to cause metaphase arrest is
A. doxorubicin
B. asparaginase
C. etoposide
D. vincristine
E. mercaptopurine - correct answerD. vincristine
The monoclonal antibody that inhibits vascular endothelial growth factor (VEGF) and
new blood vessel formation is
,A. imatinib
B. trastuzumab
C. bevacizumab
D. gefitinib
E. cetuximab - correct answerC. bevacizumab
Which of the following is true of chemotherapy?
A. one of the early goals of chemotherapy is remission
B. antineoplastic drugs only attack cancerous cells
C. drug resistance is increased with combination therapy
D. it is the primary form of treatment for solid tumors
E. it is usually effective after one treatment - correct answerA. one of the early goals of
chemotherapy is remission
Select the correct statements for alkylating drugs.
A. bind irreversibly with nucleic acids
B. decrease cells' ability to synthesize proteins
C. are cell-cycle nonspecific
D. bind irreversibly with nucleic acids
E. all statements are true - correct answerE. all statements are true
The mechanisms of actions for the antimetabolites include
A. preventing DNA replication
B. blocking DNA synthesis
C. forming abnormal nucleotides
D. preventing DNA replication and forming abnormal nucleotides
E. all of these - correct answerE. all of these
Select the correct statements about the plant extract treatments for cancer.
A. they can bind to microtubules
B. they induce enzymes
C. they increase DNA strand breakage
D. they can bind to microtubules, and they increase DNA strand breakage
E. all statements are true - correct answerD. they can bind to microtubules, and they
increase DNA strand breakage
Barbiturate and benzodiazepine hypnotics both
A. increase NREM stage 2 sleep
B. increase REM sleep
C. increase NREM stage 4 sleep
D. cause REM rebound
E. all of these statements are true - correct answerA. increase NREM stage 2 sleep
Disadvantages to the use of barbiturate hypnotics include
A. development of drug tolerance
B. risk of drug dependency
, C. disruption of normal stages of sleep
D. suppression of REM sleep
E. all of these statements are true - correct answerE. all of these statements are true
The correct statement concerning the use of hypnotic drugs is A. zolpidem binds to the
GABA receptor
B. benzodiazepines increase chloride channel opening
C. barbiturates block the GABA receptor
D. ramelteon is a melatonin antagonist
E. flumazenil is a benzodiazepine receptor agonist - correct answerB. benzodiazepines
increase chloride channel opening
Flurazepam
A. is classified as long-acting
B. forms active metabolites
C. may cause next-day residual effects
D. increases chloride ion influx
E. all of these statements are true - correct answerE. all of these statements are true
Eszopiclone
A. is classified as a benzodiazepine
B. has a half-life of 1-2 hours
C. increases total sleep time
D. is used as an antianxiety agent
E. is also used as an anticonvulsant - correct answerC. increases total sleep time
Zolpidem
A. binds to the alpha-1 subunit of the GABA A receptor
B. is useful as a muscle relaxant
C. has a slow onset of action
D. is useful as an anticonvulsant
E. is chemically classified as a benzodiazepine - correct answerA. binds to the alpha-1
subunit of the GABA A receptor
Alcohol has pharmacological effects on which body systems? A. central nervous system
B. gastrointestinal system
C. renal system
D. vascular system
E. all of these - correct answerE. all of these
The main pharmacologic effect of the SSRIs is
A. increase levels of norepinephrine
B. increase levels of serotonin
C. decrease levels of norepinephrine
D. decrease levels of serotonin
E. decrease levels of dopamine - correct answerB. increase levels of serotonin
