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ISBB MTAP 2024 /2025 EXAM QUALIFICATION QUESTIONS WITH CORRECT ANSWERS

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ISBB MTAP 2024 /2025 EXAM QUALIFICATION QUESTIONS WITH CORRECT ANSWERS. 3 situations when the antibody may appear - CORRECT ANSWER1. Transfusion 2. Preganancy 3. Transplantation A gene codes for the production of - CORRECT ANSWERn-acetyl galactosaminyl transferase A prerequisite for A and B antigen to attach in the RBC - CORRECT ANSWERH antigen A rare phenotype in which patient lacks H antigen - CORRECT ANSWERBombay Phenotype (Oh) ABO antibodies develop around - CORRECT ANSWER3-6 months of age

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ISBB MTAP 2024 /2025 EXAM QUALIFICATION
QUESTIONS WITH CORRECT ANSWERS.

3 situations when the antibody may appear - CORRECT ANSWER✅✅1. Transfusion

2. Preganancy

3. Transplantation



A gene codes for the production of - CORRECT ANSWER✅✅n-acetyl galactosaminyl transferase



A prerequisite for A and B antigen to attach in the RBC - CORRECT ANSWER✅✅H antigen



A rare phenotype in which patient lacks H antigen - CORRECT ANSWER✅✅Bombay Phenotype (Oh)



ABO antibodies develop around - CORRECT ANSWER✅✅3-6 months of age



ABO antibodies include - CORRECT ANSWER✅✅Anti-A, Anti-B, Anti-AB



ABO antigen develop as early as - CORRECT ANSWER✅✅37th day of fetal life



Acquired or specific immunity - CORRECT ANSWER✅✅adaptive immunity



Additional procedures for antibody identification - CORRECT ANSWER✅✅1. Enzyme treatment

2. Inhibition/Neutralization

3. Direct Antiglobulin Test (DAT)

4. Elution

5. Adsorption

,Anti-I is neutralized by - CORRECT ANSWER✅✅Human breast milk



Anti-P1 is neutralized by - CORRECT ANSWER✅✅hydatid cyst fluid, pigeon droppings, turtledove's egg
whites



Antibodies are found in - CORRECT ANSWER✅✅serum/plasma



Antibody identification have the same first 3 steps as antibody screening. What additional step is done
in antibody identification? - CORRECT ANSWER✅✅Coomb's Check Cells



Antibody identification have the same first 3 steps as antibody screening. What additional step is done
in antibody identification? - CORRECT ANSWER✅✅Coomb's Check Cells



Antibody identification is used in order to - CORRECT ANSWER✅✅identify the antibody that caused a
positive screen



Antibody identification is used in order to - CORRECT ANSWER✅✅identify the antibody that caused a
positive screen



Antibody screening is done three phases: - CORRECT ANSWER✅✅1. Intermediate spin

2. 37°C with enhancement media

3. AHG phase



Antibody screening is done three phases: - CORRECT ANSWER✅✅1. Intermediate spin

2. 37°C with enhancement media

3. AHG phase



Antigens are found in - CORRECT ANSWER✅✅red blood cells

, Any unfavorable transfusion-related event occurring in a patient during or after transfusion of blood
components - CORRECT ANSWER✅✅Transfusion reaction



Associated with physical RBC damage, depletion and dilution of coag factors and platelets, hypothermia,
citrate toxicity, hypokalemia or hyperkalemia - CORRECT ANSWER✅✅Physically or Chemically Induced
TR



Autocontrol - CORRECT ANSWER✅✅Patient Red Cells + Patient Serum



B gene codes for the production of - CORRECT ANSWER✅✅galactosyl transferase



B-cell comprises ____% of lymphocytes - CORRECT ANSWER✅✅20-30%



Bacterial contamination in the blood bag may show - CORRECT ANSWER✅✅Clot or hemolysis or purple
or brown (murky) discoloration



Before adding AHG, do not forget to do - CORRECT ANSWER✅✅Washing (three times)



Can weak D produce anti-D? - CORRECT ANSWER✅✅Yes.



Categories of Immunity - CORRECT ANSWER✅✅Innate

Adaptive



Caused by transfusion of IgA positive blood to IgA deficient recipients who have developed Anti-IgA -
CORRECT ANSWER✅✅Anaphylactic TR



Causes of Weak D expression - CORRECT ANSWER✅✅- Genetic Weak D

- C-trans or "positional effect"

- Partial D or Mosaic D

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