ASCP Hematology
ACTUAL 2025-2026 EXAM
Review WITH
QUESTIONS AND
CORRECT VERIFIED
ANSWERS GRADED A+
GUARANTEED 100%
PASS
Which growth factors stimulate the lymphocyte lineage? - ANSWERS-IL-2, IL-4, IL-6, IL-
7
Which protein functions in the transport of Fe? - ANSWERS-transferrin
What is the major storage form of Fe? - ANSWERS-ferritin
What is the long-term (H20) insoluble Fe storage form called? - ANSWERS-
hemosiderin
,Excess Iron is stored where? What does this cause? - ANSWERS-tissues and body
organs, hemosiderosis, hemochromatosis
Porphyrias are attributed to? - ANSWERS-excessive formation of porphrins due to
blockages in any enzymatic step in the heme synthesis pathway.
Red or port wine colored urine can be seen in which condition related to the build up of
heme precursors? - ANSWERS-porphyria
Neuropsychiatirc symptoms are seen when a build up of which precursors occurs? -
ANSWERS-early precursors (Delta-aminolevulinic acid/Porphobilinogen)
Cutaneous symptoms such as photo-sensitivity and facial hair are seen when a build up
of which precursors occurs? - ANSWERS-later precursors
(uroporphyrinogen/coproporphyrinogen, protoporphyrin/heme)
Synthesis of heme requires what two components? - ANSWERS-iron, protoporphyrin
What are the heme precursors in order of synthesis? - ANSWERS-(1)delta-
aminolevulinic acid, (2)porphobilinogen, (3)uroporphyrinogen, (4)coproporphyrinogen,
(5)protoporphyrin, (6)heme
What type of hemoglobin is seen primarily in newborns? - ANSWERS-Hgb F
What type of hemoglobin is seen primarily in adults? - ANSWERS-Hgb A2
What type of hemoglobin is rarely seen in adults as well as newborns? - ANSWERS-
Hgb A
What hemoglobin types are seen in embryos but not in adults or newborns? -
ANSWERS-gower I, gower II, portland
All non-embryonic hemoglobin types are comprised of what type of globin chain? -
ANSWERS-alpha
Hemoglobin A2 is composed of what types of globin chains? - ANSWERS-alpha, beta
Hemoglobin A is composed of what types of globin chains? - ANSWERS-alpha, delta
Hemoglobin F is composed of what types of globin chains? - ANSWERS-alpha, gamma
Multiple transfusions can cause what kind of shift in the hemoglobin-oxygen dissociation
curve? - ANSWERS-left shift
, An increase in hemoglobin F can cause what kind of shift in the hemoglobin-oxygen
dissociation curve? - ANSWERS-left shift
A left shift in the hemoglobin-oxygen dissociation curve causes what changes in the
following substances: CO2, pH, 2,3-DPG? - ANSWERS-increased pH, decreased CO2,
decreased 2,3-DPG
A right shift in the hemoglobin-oxygen dissociation curve causes what changes in the
following substances: CO2, pH, 2,3-DPG? - ANSWERS-decreased pH, increased CO2,
increased 2,3-DPG
How does EDTA work as an anticoagulant? - ANSWERS-it chelates Ca++
How does heparin work as an anticoagulant? - ANSWERS-it is an anti-thrombin agent
Hemoglobin is measured by its conversion to what? By? - ANSWERS-
cyanomethemoglobin, potassium cyanide, potassium ferricyanide
What are potential sources of error in the measurement of hemoglobin? - ANSWERS-
lipemia, icterus, high white count, resistant hemoglobins (SS, CC)
What is the normal reference range of hemoglobin for males? - ANSWERS-14-18 g/dL
What is the normal reference range of hemoglobin for females? - ANSWERS-12-16
g/dL
Methemoglobin carries iron in what state? - ANSWERS-oxidized (Fe3+)
What color is methemoglobin? - ANSWERS-brown
True or False: Methemoglobin can bind O2. - ANSWERS-false
What causes an increase in carboxyhemoglobin? - ANSWERS-smoking, carbon
monoxide poisoning
What color is carboxyhemoglobin? - ANSWERS-cherry red
What does the hematocrit measure? - ANSWERS-packed cell volume in a percentage
What are sources of error seen in using the microhematocrit method to measure the
hematocrit? - ANSWERS-failure to seal tube adequately, incorrect reading due to
uneven clay plug, inappropriate centrifuge specs, excess EDTA resulting in RBC
shrinkage
How is the hematocrit measured using automated methods? - ANSWERS-calculated
from MCV and RBC
ACTUAL 2025-2026 EXAM
Review WITH
QUESTIONS AND
CORRECT VERIFIED
ANSWERS GRADED A+
GUARANTEED 100%
PASS
Which growth factors stimulate the lymphocyte lineage? - ANSWERS-IL-2, IL-4, IL-6, IL-
7
Which protein functions in the transport of Fe? - ANSWERS-transferrin
What is the major storage form of Fe? - ANSWERS-ferritin
What is the long-term (H20) insoluble Fe storage form called? - ANSWERS-
hemosiderin
,Excess Iron is stored where? What does this cause? - ANSWERS-tissues and body
organs, hemosiderosis, hemochromatosis
Porphyrias are attributed to? - ANSWERS-excessive formation of porphrins due to
blockages in any enzymatic step in the heme synthesis pathway.
Red or port wine colored urine can be seen in which condition related to the build up of
heme precursors? - ANSWERS-porphyria
Neuropsychiatirc symptoms are seen when a build up of which precursors occurs? -
ANSWERS-early precursors (Delta-aminolevulinic acid/Porphobilinogen)
Cutaneous symptoms such as photo-sensitivity and facial hair are seen when a build up
of which precursors occurs? - ANSWERS-later precursors
(uroporphyrinogen/coproporphyrinogen, protoporphyrin/heme)
Synthesis of heme requires what two components? - ANSWERS-iron, protoporphyrin
What are the heme precursors in order of synthesis? - ANSWERS-(1)delta-
aminolevulinic acid, (2)porphobilinogen, (3)uroporphyrinogen, (4)coproporphyrinogen,
(5)protoporphyrin, (6)heme
What type of hemoglobin is seen primarily in newborns? - ANSWERS-Hgb F
What type of hemoglobin is seen primarily in adults? - ANSWERS-Hgb A2
What type of hemoglobin is rarely seen in adults as well as newborns? - ANSWERS-
Hgb A
What hemoglobin types are seen in embryos but not in adults or newborns? -
ANSWERS-gower I, gower II, portland
All non-embryonic hemoglobin types are comprised of what type of globin chain? -
ANSWERS-alpha
Hemoglobin A2 is composed of what types of globin chains? - ANSWERS-alpha, beta
Hemoglobin A is composed of what types of globin chains? - ANSWERS-alpha, delta
Hemoglobin F is composed of what types of globin chains? - ANSWERS-alpha, gamma
Multiple transfusions can cause what kind of shift in the hemoglobin-oxygen dissociation
curve? - ANSWERS-left shift
, An increase in hemoglobin F can cause what kind of shift in the hemoglobin-oxygen
dissociation curve? - ANSWERS-left shift
A left shift in the hemoglobin-oxygen dissociation curve causes what changes in the
following substances: CO2, pH, 2,3-DPG? - ANSWERS-increased pH, decreased CO2,
decreased 2,3-DPG
A right shift in the hemoglobin-oxygen dissociation curve causes what changes in the
following substances: CO2, pH, 2,3-DPG? - ANSWERS-decreased pH, increased CO2,
increased 2,3-DPG
How does EDTA work as an anticoagulant? - ANSWERS-it chelates Ca++
How does heparin work as an anticoagulant? - ANSWERS-it is an anti-thrombin agent
Hemoglobin is measured by its conversion to what? By? - ANSWERS-
cyanomethemoglobin, potassium cyanide, potassium ferricyanide
What are potential sources of error in the measurement of hemoglobin? - ANSWERS-
lipemia, icterus, high white count, resistant hemoglobins (SS, CC)
What is the normal reference range of hemoglobin for males? - ANSWERS-14-18 g/dL
What is the normal reference range of hemoglobin for females? - ANSWERS-12-16
g/dL
Methemoglobin carries iron in what state? - ANSWERS-oxidized (Fe3+)
What color is methemoglobin? - ANSWERS-brown
True or False: Methemoglobin can bind O2. - ANSWERS-false
What causes an increase in carboxyhemoglobin? - ANSWERS-smoking, carbon
monoxide poisoning
What color is carboxyhemoglobin? - ANSWERS-cherry red
What does the hematocrit measure? - ANSWERS-packed cell volume in a percentage
What are sources of error seen in using the microhematocrit method to measure the
hematocrit? - ANSWERS-failure to seal tube adequately, incorrect reading due to
uneven clay plug, inappropriate centrifuge specs, excess EDTA resulting in RBC
shrinkage
How is the hematocrit measured using automated methods? - ANSWERS-calculated
from MCV and RBC
