BIOC 384 – EXAM 3 2026 WITH 100%
ACCURATE SOLUTIONS
We eat foods containing sucrose (tablesugar), lactose (milk
sugar), and cellobiose (disaccharide of cellulose in plants).
How many netmoles of ATP per mole disaccharide do
humansgenerate from the disaccharides sucrose,
lactose,and cellobiose using the glycolytic pathway? –
Answer ☑️sucrose: 4 ATP; lactose: 4 ATP; cellobiose: 0 ATP
Which metabolic pathway is an example of a catabolic
pathway in animals? – Answer ☑️Glycogen degradation
A regulatory enzyme that controls cell division undergoes a
mutation preventing it from beingphosphorylated at a Ser
residue required for activation. However, the amino acid that
replaces Ser results inthe enzyme being catalytically active
even though this amino acid replacement is not
phosphorylated.
,1) Which amino acid listed below could be the replacement
amino acid that fits the description above?
2) What is the most likely explanation for why the mutated
enzyme results in cancer cell growth?
3) Which amino acid listed below could be a replacement
amino acid that results in an inactive enzyme? –
Answer ☑️1) Asp, 2) The regulatory enzyme cannot be
inhibited by a phosphatase enzyme, 3) Gly
Competitive inhibitors alter the Km , but not the Vmax
,uncompetitive inhibitors alter the Vmax and the Km , mixed
inhibitorsdecrease Vmax and increase or decrease Km , and
noncompetitiveinhibitors decrease Vmax , but do not alter
the K m . Identify each ofthe inhibitors depicted in the box to
the right as functionaldiagrams (1 and 2), or in L-B plots (3
and 4) – Answer ☑️1) uncompetitive inhibitor, 2)
competitive inhibitor,3) uncompetitive inhibitor, 4)
competitive inhibitor
Put the following nine signaling events in the correct order
starting with release of insulin from thepancreatic beta cells
and ending with increased glucose uptake into cells by
GLUT4 glucose transporter.
,___Tyrosine phosphorylation of insulin receptor substrate-1.
___Binding of IRS-1 to phosphotyrosine on the insulin
receptor.
___Phosphorylation of downstream target proteins by Akt.
___Binding of phosphoinositide 3-kinase to phosphotyrosine
on IRS-1.
___Insulin binding to one of the a subunits of the insulin
receptor.
___PDK-1 and Akt binding to phosphatidylinositol-3,4,5-
trisphosphate.
___Phosphorylation of phosphatidylinositol-4,5-
bisphosphate by PI3K.
___Tyr phosphorylation of the cytosolic domains of insulin
receptor.
___PDK-1 phosphorylation and activation of Akt kinase
activity. – Answer ☑️4, 3, 9, 5, 1, 7, 6, 2, 8
Dexamethasone (Dex) is a high affinity ligand for the
glucocorticoid receptor (GR), which hasbeen used as an
anti-inflammatory drug to treat rheumatoid arthritis. What is
the molecular explanation forwhy Dex is 50 times more
potent in treating inflammation than the natural
, glucocorticoid cortisol? – Answer ☑️Dex binding to GR is
50 times more efficient at shifting GR to the active R state
conformation
Metabolic flux is regulated by availability of substrates and
enzymeactivity. Using the table below, match the
mechanism by which enzyme activity isregulated (A, B, C)
with example(s) of the most common modes of
cellularregulation (1-9). Examples of cellular regulation are
used once, more than once,or not all. All examples of
enzyme regulation are used at least once.
Enzyme Regulation
A. Enzyme levels
B. Catalytic activity
C. Compartmentation
Cellular Respiration
1. Allosteric control
2. Tissue localization
3. DNA mutation
4. Subcellular localization
5. Membrane fluidity
ACCURATE SOLUTIONS
We eat foods containing sucrose (tablesugar), lactose (milk
sugar), and cellobiose (disaccharide of cellulose in plants).
How many netmoles of ATP per mole disaccharide do
humansgenerate from the disaccharides sucrose,
lactose,and cellobiose using the glycolytic pathway? –
Answer ☑️sucrose: 4 ATP; lactose: 4 ATP; cellobiose: 0 ATP
Which metabolic pathway is an example of a catabolic
pathway in animals? – Answer ☑️Glycogen degradation
A regulatory enzyme that controls cell division undergoes a
mutation preventing it from beingphosphorylated at a Ser
residue required for activation. However, the amino acid that
replaces Ser results inthe enzyme being catalytically active
even though this amino acid replacement is not
phosphorylated.
,1) Which amino acid listed below could be the replacement
amino acid that fits the description above?
2) What is the most likely explanation for why the mutated
enzyme results in cancer cell growth?
3) Which amino acid listed below could be a replacement
amino acid that results in an inactive enzyme? –
Answer ☑️1) Asp, 2) The regulatory enzyme cannot be
inhibited by a phosphatase enzyme, 3) Gly
Competitive inhibitors alter the Km , but not the Vmax
,uncompetitive inhibitors alter the Vmax and the Km , mixed
inhibitorsdecrease Vmax and increase or decrease Km , and
noncompetitiveinhibitors decrease Vmax , but do not alter
the K m . Identify each ofthe inhibitors depicted in the box to
the right as functionaldiagrams (1 and 2), or in L-B plots (3
and 4) – Answer ☑️1) uncompetitive inhibitor, 2)
competitive inhibitor,3) uncompetitive inhibitor, 4)
competitive inhibitor
Put the following nine signaling events in the correct order
starting with release of insulin from thepancreatic beta cells
and ending with increased glucose uptake into cells by
GLUT4 glucose transporter.
,___Tyrosine phosphorylation of insulin receptor substrate-1.
___Binding of IRS-1 to phosphotyrosine on the insulin
receptor.
___Phosphorylation of downstream target proteins by Akt.
___Binding of phosphoinositide 3-kinase to phosphotyrosine
on IRS-1.
___Insulin binding to one of the a subunits of the insulin
receptor.
___PDK-1 and Akt binding to phosphatidylinositol-3,4,5-
trisphosphate.
___Phosphorylation of phosphatidylinositol-4,5-
bisphosphate by PI3K.
___Tyr phosphorylation of the cytosolic domains of insulin
receptor.
___PDK-1 phosphorylation and activation of Akt kinase
activity. – Answer ☑️4, 3, 9, 5, 1, 7, 6, 2, 8
Dexamethasone (Dex) is a high affinity ligand for the
glucocorticoid receptor (GR), which hasbeen used as an
anti-inflammatory drug to treat rheumatoid arthritis. What is
the molecular explanation forwhy Dex is 50 times more
potent in treating inflammation than the natural
, glucocorticoid cortisol? – Answer ☑️Dex binding to GR is
50 times more efficient at shifting GR to the active R state
conformation
Metabolic flux is regulated by availability of substrates and
enzymeactivity. Using the table below, match the
mechanism by which enzyme activity isregulated (A, B, C)
with example(s) of the most common modes of
cellularregulation (1-9). Examples of cellular regulation are
used once, more than once,or not all. All examples of
enzyme regulation are used at least once.
Enzyme Regulation
A. Enzyme levels
B. Catalytic activity
C. Compartmentation
Cellular Respiration
1. Allosteric control
2. Tissue localization
3. DNA mutation
4. Subcellular localization
5. Membrane fluidity
