2026 COMPLETE QUESTIONS AND ANSWERS
◉ In which two conditions are chromosomal abnormalities the leading
known cause?
Intellectual disability
Respiratory disorders
Fetal miscarriage
Cardiovascular disease
Mental illness
Check My Answer . Answer: Intellectual disability and fetal
miscarriage. Chromosome abnormalities are the leading known cause of
intellectual disability and fetal miscarriage.
◉ What are three examples of prenatal diagnostic studies?
Drug-sensitivity testing
Chorionic villus sampling (CVS)
Microscopy of cervical mucosa
Preimplantation genetic testing (PGT)
,Amniocentesis . Answer: Chorionic villus sampling (CVS),
amniocentesis, and preimplantation genetic testing (PGT) are examples
of prenatal diagnostic studies and are performed in vitro. CVS is a form
of genetic testing that provides genetic information found in utero and is
usually performed between weeks 11 and 14 of pregnancy. An
amniocentesis is a form of genetic testing that evaluates amniotic fluid
and is usually performed during the second trimester, between weeks 15
and 20 of pregnancy. PGT is performed on the embryo prior to
implantation.
◉ Which genetic disorder is characterized by the presence of a zygote
having one chromosome with a normal complement of genes and one
chromosome with a missing gene?
Klinefelter syndrome
Down syndrome
Cri du chat syndrome
Turner syndrome . Answer: Cri du chat syndrome (translated as "cry of
the cat") is caused by a DNA deletion. This term describes the cry often
heard from a baby affected by the syndrome. Cri du chat syndrome can
present as a microcephalic, low birth-weight baby with a piercing cry.
◉ How can an X-linked recessive disease skip generations?
Mothers cannot pass X-linked genes to their sons.
Females are hemizygous for the X chromosome.
, The disease can be transmitted through female carriers.
These diseases need only one copy of the gene in females. . Answer:
The disease can be transmitted through female carriers.
Since females have two copies of the X chromosome, the mother may
provide an unaffected X to a daughter or son. Furthermore, a daughter
may not show signs of the disease because she has the other X (the only
X the father can give to a female) to cancel it out.
◉ Which type of risk is referred to as the ratio of the disease rate among
the entire population to the disease rate in an unexposed population?
Relative
Attributable
Contingency
Causal . Answer: Relative risk is a ratio of probability, not an actual
occurrence of disease.
◉ What are the empirical risks for most multifactorial diseases based
on?
Direct observation
Chromosomal testing
Relative risks