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RNSG 1201 Exam 1 Questions with Answers (100% Correct Answers)

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RNSG 1201 Exam 1 Questions with Answers (100% Correct Answers)

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RNSG 1201 Exam 1 Questions with Answers (100%
Correct Answers)

Pharmaceutics Answer: The science of preparing and dispensing

drugs, including dosage form design.

Pharmacodynamics Answer: The study of what the drug does to the

body (biochemical and physiological interactions of drugs at their sites

of activity)

Pharmacoeconomics Answer: The study of economic factors impacting

the cost of drug therapy.

Pharmacogenomics Answer: The study of the influence of genetic

factors on drug response that result in the absence, overabundance, or

insufficiency of drug-metabolizing enzymes

Pharmacognosy Answer: The study of drugs that are obtained from

natural plant and animal sources.

Pharmacokinetics Answer: The study of what happens to a drug from

the time it is put into the body until the parent drug and all




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metabolites have left the body; What the body does to the drugs;

absorbed, distributed within the body, metabolized, and excreted.

Absorption Answer: The transport of dissolved substances into cells.

Bioavailability Answer: A measure of the extent of drug absorption for

a given drug and route (from 0% to 100%). reduced by first pass effect,

Oral medication has a bioavailability of less than 100% and IV is 100%

first pass effect Answer: The initial metabolism in the liver of a drug

absorbed from the gastrointestinal tract before the drug reaches

systemic circulation through the bloodstream. Chemically change into

metabolite in the liver

Distribution Answer: transport of a drug by the bloodstream to its site

of action. Albumin- most common blood protein and carries the

majority of protein bound molecules.

Metabolism (biotransformation) Answer: One or more biochemical

reactions involving a parent drug; occurs mainly in the liver and

produces a metabolite that is either inactive or active. Also known as

metabolism.




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Cytochrome P450 enzymes Answer: The general name for a large class

of enzymes that play a significant role in drug metabolism and drug

interactions. (microsomal enzymes)

Excretion Answer: Process by which metabolic wastes are eliminated

from the body: Renal excretion ; biliary excretions

half-life Answer: time required for half (50%) of a given drug to be

removed from the body

steady state Answer: The physiologic state in which the amount of

drug removed via elimination is equal to the amount of drug absorbed

with each dose; need medication to be at the same level or a steady

level

peak level Answer: highest blood level of a drug / too high = toxic

trough level Answer: The lowest concentration of drug reached in the

body after it falls from its peak level, usually measured in a blood

sample for therapeutic drug monitoring.

Toxicity occurs Answer: If the peak level of blood is too high

Pharmacology Answer: The broadest term for the study or science of

drugs
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