Solutions
Pharmacokinetics
Body does to drug-absorption, metabolism, distribution,
excretion
Pharmacodynamics
What does drug due to body, body's response to drug
Affinity
strength of attraction between drug and receptor, increase
affinity=decreased dose requirements
PUD and H. Pylori First line tx
PPI BID + antibiotic (amoxicillin) + antibiotic (Clarithromycin)
daily for 14 days
PUTD and H. Pylori Second line of treatment
PPI BID + Metronidazol + Tetracycline + Bismuth Subsalicylate
for 14 days
Adverse reactions are what
Drug induced toxic reaction, causes patient to stop taking the
drug
Define Mechanism of action
What the drug does to the body, specific chemical actions in the
body
, Define Half Life
Time for plasma concentration of a drug to be reduced by 50%
Diarrhea causes
bacterial, virus, food intolerance, food allergy, parasite,
medicine reaction, IBS, Inflammatory bowel disease, antibiotic
use, metabolic conditions thyroid problems, radiation
treatments, tumors
Heartburn treatment when PRN options fail
Ranitidine (Zantac) BID H2 blocker
Nexium (PPI) MOA:
Suppress gastric acid by inhibition of H+/K+ ATpase pump in
parietal cells of stomach
Seasonal allergies 1st line treatment
2nd generation antihistamine, Claritin, less sedating than 1st line
Asthma in children diagnosis and treatment
symptoms 3-4x a month at night with goals of infrequent
albuterol symptoms relief, regular kids lives participate in sports
activities
Asthma during pregnancy safe treatment
Budesonide
Adults-mild persistent asthma dx, tx, evaluation