EKU PMHNP NSC 830 EXAM QUESTIONS WITH
COMPLETE SOLUTIONS
3 processes drugs can be absorbed into cells Correct Answers
Passive diffusion, facilitated diffusion, and active transport
Absorption Correct Answers the process that occurs between
the time a drug enters the body and the time it enters the
bloodstream to be circulated
Active transport Correct Answers Drug molecules are moved
from an area of lower concentration to one of higher
concentration; requires a carrier substance and release of cellular
energy. There is work involved-active assistance is needed.
Agonist Correct Answers drugs that produce effects similar to
those produced by naturally occurring hormones,
neurotransmitters, and other natural substances.
Antagonist Correct Answers drugs that inhibit cell fx by
occupying receptor sites
Area under the curve Correct Answers plot of the plasma
concentration vs. time after a single dose of drug is administered
Bio-availability Correct Answers % of drug that reaches
systemic circulation after an administered dose. Used to
determine drug dose.
C-max Correct Answers maximum (peak) concentration of a
drug after it is administered
, Efficacy Correct Answers The maximum effect a drug can
achieve
Facilitated diffusion Correct Answers drug molecules combine
w a carrier/facilitator substance, such as an enzyme or protein to
go from a higher concentration to a lower concentration
First-Pass effect Correct Answers Some drugs, when passing
from the intestines to the liver, get metabolized with only part of
drug dose reaching systemic circulation for distribution
Half-Life Correct Answers the time required for the serum
concentration of a drug to decrease by 50%
IM/SC route is absorbed Correct Answers There is no first-pass
effect, it is affected by the blood flow, must be mixed w/
oil/suspension or it takes longer to absorb and act. Absorbed
through the liver.
IV route is absorbed Correct Answers Directly into the blood
stream
Metabolism Correct Answers the breaking down of the drug,
also called-Biotransformation
Minimal effective Concentration Correct Answers The minimal
blood level at which the drug exerts the desired effect
Most PO drugs are absorbed in the Correct Answers small
intestine
COMPLETE SOLUTIONS
3 processes drugs can be absorbed into cells Correct Answers
Passive diffusion, facilitated diffusion, and active transport
Absorption Correct Answers the process that occurs between
the time a drug enters the body and the time it enters the
bloodstream to be circulated
Active transport Correct Answers Drug molecules are moved
from an area of lower concentration to one of higher
concentration; requires a carrier substance and release of cellular
energy. There is work involved-active assistance is needed.
Agonist Correct Answers drugs that produce effects similar to
those produced by naturally occurring hormones,
neurotransmitters, and other natural substances.
Antagonist Correct Answers drugs that inhibit cell fx by
occupying receptor sites
Area under the curve Correct Answers plot of the plasma
concentration vs. time after a single dose of drug is administered
Bio-availability Correct Answers % of drug that reaches
systemic circulation after an administered dose. Used to
determine drug dose.
C-max Correct Answers maximum (peak) concentration of a
drug after it is administered
, Efficacy Correct Answers The maximum effect a drug can
achieve
Facilitated diffusion Correct Answers drug molecules combine
w a carrier/facilitator substance, such as an enzyme or protein to
go from a higher concentration to a lower concentration
First-Pass effect Correct Answers Some drugs, when passing
from the intestines to the liver, get metabolized with only part of
drug dose reaching systemic circulation for distribution
Half-Life Correct Answers the time required for the serum
concentration of a drug to decrease by 50%
IM/SC route is absorbed Correct Answers There is no first-pass
effect, it is affected by the blood flow, must be mixed w/
oil/suspension or it takes longer to absorb and act. Absorbed
through the liver.
IV route is absorbed Correct Answers Directly into the blood
stream
Metabolism Correct Answers the breaking down of the drug,
also called-Biotransformation
Minimal effective Concentration Correct Answers The minimal
blood level at which the drug exerts the desired effect
Most PO drugs are absorbed in the Correct Answers small
intestine
