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NR 293 Pharmacology – ATI Review (2025) – Comprehensive exam questions with answers and rationales

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This document contains an extensive collection of ATI NR 293 Pharmacology review questions with correct answers and detailed rationales. It covers a wide range of medication classes, clinical scenarios, adverse effects, contraindications, and nursing considerations. The material is organized as a full exam-style question bank, useful for reviewing core pharmacology content and preparing for ATI and nursing school exams. It appears to be a complete study resource for the 2025 academic year.

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ATI NR 293 PHARM REVIEW
QUESTIONS AND ANSWERS
VERIFIED & LATEST UPDATE
2025




• A nurse is preparing a client for surgery. Prior to administering the prescribed hydroxyzine, the
nurse should explain to the client that the medication is for which of the following indications?
(Select all that apply.)
a) Controlling
emesis b)
Diminishing
anxiety
c) Reducing the amount of narcotics needed for pain relief

, d) Preventing thrombus formation
e) Drying secretions


• A nurse is caring for a client who has acute respiratory distress syndrome (ARDS), and
requires mechanical ventilation. The client receives a prescription for pancuronium. The nurse
recognizes that this medication is for which of the following purposes?


a) Decrease chest wall compliance


b) Suppress respiratory effort


i) Rationale: Neuromuscular blocking agents, such as pancuronium, induce paralysis and
suppress the client's respiratory efforts to the point of apnea, allowing the mechanical
ventilator to take over the work of breathing for the client. This therapy is especially

, helpful for a client who has ARDS and poor lung compliance.


c) Induce sedation


d) Decrease respiratory secretions




• A nurse is caring for a client who is taking lisinopril. Which of the following outcomes
indicates a therapeutic effect of the medication?
a) Decreased blood pressure
i) Rationale: Lisinopril, an ACE inhibitor, may be used alone or in combination
with other antihypertensives in the management of hypertension and
congestive heart failure. A therapeutic effect of the medication is a decrease in
blood pressure.
b) Increase of HDL cholesterol
i) Rationale: This is not an intended effect of lisinopril.
c) Prevention of bipolar manic episodes
i) Rationale: This is not an intended effect of lisinopril.
d) Improved sexual function
i) Rationale: This is not an intended effect of lisinopril. Lisinopril may in fact cause
sexual dysfunction and impotence.

, • A nurse is caring for a client who has poison ivy and is prescribed diphenhydramine. Which of
the following instructions should the nurse give regarding the adverse effect of dry mouth
associated with diphenhydramine?
a) Administer the medication with food
b) Chew on sugarless gum or suck on hard, sour candies


i) Rationale: Clients who report dry mouth can get the most effective relief by
sucking on hard candies (especially the sour varieties that stimulate
salivation), chewing gum, or rinsing the mouth frequently. It is the local effect
of these actions that provides comfort to the client.
c) Place a humidifier at your bedside every evening
d) Discontinue the medication and notify your provider
• A nurse on an oncology unit is preparing to administer doxorubicin to a client who has breast
cancer. Prior to beginning the infusion, the nurse verifies the client's current cumulative lifetime
dose of the medication. For which of the following reasons is this verification necessary?


a) An excess amount of doxorubicin can lead to myelosuppression.


b) Exceeding the lifetime cumulative dose limit of doxorubicin might cause extravasation.


c) An excess amount of doxorubicin can lead to cardiomyopathy.

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