pathophysiology the biologic basis for disease in adult and children

pathophysiology the biologic basis for
disease in adult and children

1. Discuss genetic testing and its implications. When might you recommend
genetic testing? - Correct Answer -



1.What is the role of the cell membrane - Correct Answer - Express self-
antigens to prevent auto-immune responses & Control the intercellular
environment



2. What happens if mRNA is genetically damaged? - Correct Answer -
Potential for coded protein to be damaged



3. What would happen if the Endoplasmic Reticulum was damaged? -
Correct Answer - proteins could be malformed, rejected, or not sent to Golgi
Apparatus, causing multiple pathologies without the ER or genetically
altered ER. The Endoplasmic Reticulum (ER) supports homeostasis in the cell
and subsequently in the body. It is the organelle responsible for folding newly
synthesized proteins before they are exported to the Golgi Apparatus for
packing and shipping. Another important function of the ER is helping to
regulate the calcium-ROS balance. Lipid biosynthesis is a third role the ER
plays in the cell.



4. What pathology would you expect if the cytoskeleton the cilia were
paralyzed by cigarette smoke? - Correct Answer - Disrupt the intercellular
movement and cellular motility by their effect on microtubules and
microfilaments



Mr. Turin had a severe crush injury of both lower extremities when his house
collapsed during a tornado. Among other abnormal values, Why and what are