BIO 322 Exam 3 Study Guide 2025: Advanced Biology Practice Questions

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EXAM 3: BIO322 / BIO 322 (LATEST 2025 UPDATE)

APPLIED PATHOPHYSIOLOGY EXAM | QUESTIONS

AND VERIFIED ANSWERS | 100% CORRECT | GRADE

A - GCU

Which of the following does NOT apply to the reaction

catalyzed by the pyruvate dehydrogenase complex?

.....ANSWER.....Each intermediate in the five step reaction is able

to diffuse to the next active site in a sequential manner.

Which of the following enzymes catalyzes a reaction of the citric

acid cycle that does NOT produce reduced electron carriers?

.....ANSWER.....Succinyl-CoA synthetase

All of the enzymes of the citric acid cycle are located in the

mitochondrion. .....ANSWER.....True

The citric acid cycle is classed as a reductive pathway as it

produces reduced electron carriers. .....ANSWER.....False

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Acetyl CoA is a feed forward activator of the enzyme ________

ensuring sufficient oxaloacetate for the citric acid cycle to

continue. .....ANSWER.....Pyruvate carboxylase

Taking one mole of glucose through glycolysis and the citric acid

cycle generates: .....ANSWER.....6C02, 10 NADH/H+, 2FADH2

and 4 ATP.

ATP synthase can produce ATP using as a direct energy source:

.....ANSWER.....Energy from a proton gradient established across

the inner mitochondrial membrane

Which of the following is correct concerning the mitochondrial

ATP synthase? .....ANSWER.....It catalyzes ATP synthesis by a

rotational catalysts mechanism

During oxidative phosphorylation, the proton motive force that is

generated by electron transport is used to: .....ANSWER.....drive

the synthesis of ATP as protons flow passively back into the

matrix through a proton pore assiciated with ATP synthase

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Which of the following statements is FALSE?




-All of the protein complexes of the mitochondrial respiratory

chain are bound in the inner mitochondrial membrane

-Cytochrome c and coenzyme Q are both soluble electron

carriers that are loosely attached to the outside of the inner

mitochondrial membrane.

-Oxygen is reduced to water at complex IV of the mitochondrial

respiratory chain.

-During electron transport protons are pumped across the inner

mitochondrial membrane from the matrix to the intermembrane

space. .....ANSWER.....Cytochrome c and coenzyme Q are both

soluble electron carriers that are loosely attached to the outside

of the inner mitochondrial membrane.

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Which of the following is NOT an electron acceptor in the

mitochondrial respiratory chain?




CoQH2

FMN

Fe3+

FAD .....ANSWER.....CoQH2

Electron transport through NADH-Coenzyme Q reductase

(Complex I) is accompanied by transfer of ________ protons

from the matrix to the intermembrane space. (answer with the

number. e.g.: 6) .....ANSWER.....4

How do the mitochondria maintain the chemiosmotic gradient

used for the electron transport chain? .....ANSWER.....They

continuously pump protons from the mitochondrial matrix into the

intermembrane space