Page 1 of 34
Exam 1 - NUR2474 / NUR 2474 (Latest 2025) :
Pharmacology for Professional Nursing - Rasmussen
Cholinesterase inhibitors .....ANSWER.....Donepezil
Rivastigmine
Galantamine
neostigmine
Cholinesterase inhibitors side effects .....ANSWER.....dizziness, GI
upset, fatigue, headache
cholinesterase inhibitors adverse affects
.....ANSWER.....bradycardia bronchoconstriction
cholinesterase inhibitors interactions
.....ANSWER.....Anticholinergics, first generation anithistamines,
TCA's, conventional antipsychotics
,Page 2 of 34
Donzepil side effects .....ANSWER.....nausea vomitting diarrhea
urinary urgency bronchoconstriction bradycardia orthostatic
hypotension
rivastigmine .....ANSWER.....side effects likely and more intense.
caution with PUD bradycardia sick sinus syndrome urinary
obstruction, lung disease. transdermal route lowers intensity of
side effects.
neostigmine .....ANSWER.....prevents acetylcholine degradation.
myasthenia gravis, parkinsons dementia, alzheimers
Galantamine .....ANSWER.....caution use in asthma or copd .
avoid anticholinergics 1st gen antihistamines, TCAs, conventional
antipsychotics because they reduce effects.
nmda blocker .....ANSWER.....antagonist.
Memantime .....ANSWER.....NMDA blocker
,Page 3 of 34
Memantime adverse reactions .....ANSWER.....skin reactions.
steven johnsons syndrome. erythema multiforme. bradycardia,
hypertensions, angina.
Memantime side effects .....ANSWER.....dizziness headache
confusion diarrhea or constipation
Immunomodulators .....ANSWER.....interferon beta
interferon beta .....ANSWER.....FLu like symptoms, hepatotoxicity,
myelosuppression (decreases all blood cells monistor cbc
frequently) injection site reaction. depressions
interferon beta drug interactions .....ANSWER.....other
immunosuppressive drugs
immunosuppressants .....ANSWER.....Mitoxantrone
mitoxantrone .....ANSWER.....decreases autoimmune destruction of
myelin.
, Page 4 of 34
Mitoxantrone side effects
.....ANSWER.....myelosuppression(montior cbc) increased risk for
infections. no live virus immunizations. cardiotoxicity (irreverisble
damage to ejection fraction) fetal harm (growth delay and
prematurity)
Mitoxantrone reversible injuries .....ANSWER.....hair loss, Gi
mucosa, amenorrhea, sysmptoms of allergy, acute myelogenous
leukemia.
seizure meds .....ANSWER.....IV benzos (Diazepam/lorazepam
longterm- phenytoin
what antiseizure meds do .....ANSWER.....either suppress
discharge or neurons or suppress progation of seizure activity
from the focus to other areas of the brain.
5 basic mechanisms of antiseizure drugs .....ANSWER.....suppress
sodium influx
Exam 1 - NUR2474 / NUR 2474 (Latest 2025) :
Pharmacology for Professional Nursing - Rasmussen
Cholinesterase inhibitors .....ANSWER.....Donepezil
Rivastigmine
Galantamine
neostigmine
Cholinesterase inhibitors side effects .....ANSWER.....dizziness, GI
upset, fatigue, headache
cholinesterase inhibitors adverse affects
.....ANSWER.....bradycardia bronchoconstriction
cholinesterase inhibitors interactions
.....ANSWER.....Anticholinergics, first generation anithistamines,
TCA's, conventional antipsychotics
,Page 2 of 34
Donzepil side effects .....ANSWER.....nausea vomitting diarrhea
urinary urgency bronchoconstriction bradycardia orthostatic
hypotension
rivastigmine .....ANSWER.....side effects likely and more intense.
caution with PUD bradycardia sick sinus syndrome urinary
obstruction, lung disease. transdermal route lowers intensity of
side effects.
neostigmine .....ANSWER.....prevents acetylcholine degradation.
myasthenia gravis, parkinsons dementia, alzheimers
Galantamine .....ANSWER.....caution use in asthma or copd .
avoid anticholinergics 1st gen antihistamines, TCAs, conventional
antipsychotics because they reduce effects.
nmda blocker .....ANSWER.....antagonist.
Memantime .....ANSWER.....NMDA blocker
,Page 3 of 34
Memantime adverse reactions .....ANSWER.....skin reactions.
steven johnsons syndrome. erythema multiforme. bradycardia,
hypertensions, angina.
Memantime side effects .....ANSWER.....dizziness headache
confusion diarrhea or constipation
Immunomodulators .....ANSWER.....interferon beta
interferon beta .....ANSWER.....FLu like symptoms, hepatotoxicity,
myelosuppression (decreases all blood cells monistor cbc
frequently) injection site reaction. depressions
interferon beta drug interactions .....ANSWER.....other
immunosuppressive drugs
immunosuppressants .....ANSWER.....Mitoxantrone
mitoxantrone .....ANSWER.....decreases autoimmune destruction of
myelin.
, Page 4 of 34
Mitoxantrone side effects
.....ANSWER.....myelosuppression(montior cbc) increased risk for
infections. no live virus immunizations. cardiotoxicity (irreverisble
damage to ejection fraction) fetal harm (growth delay and
prematurity)
Mitoxantrone reversible injuries .....ANSWER.....hair loss, Gi
mucosa, amenorrhea, sysmptoms of allergy, acute myelogenous
leukemia.
seizure meds .....ANSWER.....IV benzos (Diazepam/lorazepam
longterm- phenytoin
what antiseizure meds do .....ANSWER.....either suppress
discharge or neurons or suppress progation of seizure activity
from the focus to other areas of the brain.
5 basic mechanisms of antiseizure drugs .....ANSWER.....suppress
sodium influx
