NR 565 PHARMACOLOGY WEEK 4 EXAM QUESTIONS & EXACT CORRECT ANSWERS

NR 565 PHARMACOLOGY WEEK 4
EXAM QUESTIONS & EXACT
CORRECT ANSWERS

Most common inflammatory form of arthritis - correct answer ✔✔Gout



Characteristics: RA - correct answer ✔✔Rapid onset

3:1 in women/men

Age 35-50 years at onset

Affects hands and feet

local and systemic inflammation

60 mins morning joint stiffness

Symmetric

Elevated ESR

Leukocytosis

Systemic symptoms



RA symptoms - correct answer ✔✔Pain

Swelling

Warmth

Stiffness



Characteristics: Osteoarthritis - correct answer ✔✔Slow onset (years)

1:1 in men/women

Age > 50 years at onset

, Affects hands, hips, knees

Mild or local inflammation

< 30 min morning joint stiffness

symmetric or asymmetric pattern

ESR normal

Mild leukocytosis

No systemic symptoms



Symptoms: Osteoarthritis - correct answer ✔✔Pain

Bone enlargement



Treatment goals: RA - correct answer ✔✔Relieve symptoms

Maintain joint function and ROM

Decrease systemic involvement

Delay disease progression



Medications: RA - correct answer ✔✔NSAIDS

Glucocorticoids

Conventional DMARDS

Biologic DMARDS



Mechanism of action: Conventional DMARDs - correct answer ✔✔Immunosuppressant

Inhibits dihydrofolate reductase

Inhibits lymphocyte proliferation

Folate antagonist