and Correct Verified Answers/ ANCC Medical Surgical
Nursing Certification 2026 Practice Exam
Which of the following is not a symptom of Diabetes Insipidus?
A. hyponatremia
B. polydipsia
C. polyphagia
D. polyuria - ANSWER-A. hyponatremia
DI would cause hypernatremia
Which of the following medications used to treat Type 2 diabetes is least likely to
cause hypoglycemia?
A. Glimepiride (Amaryl)
B. Metformin (Glucophage)
C. Glipizide (Glucotrol)
D. Micronized glyburide (Glynase) - ANSWER-B. Metformin (Glucophage)
An assessment of a pressure injury reveals full-thickness tissue loss surrounded by
pink healing tissue with no bone, tendon, or muscle exposed. How would this
wound be classified?
A. Stage I
B. Stage II
C. Stage III
D. Stage IV - ANSWER-C. Stage III
pg. 1
,What is the #1 cause of hemorrhagic stroke?
A. alcohol abuse
B. hypertension
C. liver dysfunction
D. bleeding disorders - ANSWER-B. hypertension
Kidney failure is defined as a GFR less than:
A. 15%
B. 30%
C. 45%
D. 60% - ANSWER-A. 15%
Chronic kidney disease involves all of the following except:
A. Hypermagnesemia
B. Hypokalemia
C. Hypocalcemia
D. Hyperphosphatemia - ANSWER-B. Hypokalemia
The most likely cause of acute kidney injury in the hospitalized patient is:
A. Hypoperfusion
B. Hyperlipidemia
C. Hyperkalemia
D. Hypernatremia - ANSWER-A. Hypoperfusion
pg. 2
,To assess long term maintenance of serum glucose, the nurse will monitor results
of which ordered lab test?
A. glucose tolerance testing
B. hemoglobin A1C
C. serum insulin
D. pancreatic enzymes - ANSWER-B. hemoglobin A1C
A nurse is teaching a patient about self-insulin injection. The nurse knows which
of the following is the site of fastest absorption?
A. upper outer arm
B. buttocks
C. mid-lateral thigh
D. abdomen - ANSWER-D. abdomen
largest surface area of subcutaneous tissue
Which of the following is a systemic autoimmune disorder?
A. multiple sclerosis
B. rheumatoid arthritis
C. myasthenia gravis
D. glomerulonephritis - ANSWER-B. rheumatoid arthritis
Rheumatoid arthritis may be treated with all of the following except:
A. Methotrexate
B. Hydroxychloroquine
C. NSAIDs
pg. 3
, D. Steroids - ANSWER-B. Hydroxychloroquine
hydroxy is used for lupus
Which of the following is a symptom of Systemic Lupus Erythematosus?
A. butterfly rash over the cheeks
B. hypercoagulopathy
C. nausea
D. weight loss - ANSWER-A. butterfly rash over the cheeks
How is the absolute neutrophil count (ANC) calculated?
A. (% neutrophils + % bands) x WBCs
B. # platelets + # WBCs
C. (% neutrophils - % bands) x WBCs
D. (% neutrophils + % bands) / WBCs - ANSWER-A. (% neutrophils + % bands)
x WBCs
Neutropenia is defined as:
A. ANC < 1500
B. ANC < 1000
C. ANC < 500
D. ANC < 250 - ANSWER-C. ANC < 500
Compartment syndrome may be suspected with a pressure of:
A. 5 mmHg
B. 10 mmHg
pg. 4