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Class notes

Endocrine

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Notes on Diabetes and Endocrine Emergencies

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DIABETES TYPE I DIABETES
-

usually associated
causes
of
the body to
with autoimmune
destroy the bata
phenomenon
insulin
when

producing
a genetic abnormality
sells of the Islets
Langerhans
-

generally affects children
D EFINTrised managed by :
-




>
-

daily insulin by injection or
pump
by a deficiency of insulin or by a >
-
exercise
inability of the baby to respond to insulin >
-
diet
-
it is often associated by
SIGNS SYMPTOMS
>
-

polydipsia /increased thirsty
>
-

palyuria (excessive voine excretion) -


frequent urination
-
>
glucsuria (glucose in urinel -

weight loss
>
-


Polyphagia /excessive hunger) -
extreme thirst hunger
>
-


weight loss -

vomiting nausea
-
extreme weakness 3 fatigue
-


iroitability




TYPE 2 DIABETES GESTATIONAL DIABETES
-
results from a progressive insulin secretary deficiency decreased tissue -
form of g lucose intolerance during pregnancy normally in 3rd trimester
,



sensitivity to insulin (insulin resistances >
-

inability of the mother to metabolize Carbohydrates during pregnancy
-
insulin resistance ·
deficiency of mother's insulin
> too
-
few insulin osceptors ·
hormones secreted by placenta that blocks the action of the
>
-

faulty insulin receptors mother's insulin
in adulthood increases risk of type 2 diabetes
typically develops
- -




-
related to : -
resolves after delivery for most women
>
-
metabolic syndrome -
excessive simants of mother's glucose is transferred to the fatus
·
excessive weight around waist where it is stored as fat
·

hypertension >
-
results in large babies
·

hypercholesterolemia
>
-

genetic factors
>
-

obesity
-

managed with meds exercise diet ,

-


type 2 diabetes seen more foequently in children due to increase in shildhood
obesity
SIGNS 3 SYMPTOMS
-

irritability -

glycosuria
-
blurred vision -

polyuria
-
skin infections -
thirst
-

weight loss -
dry 3 itchy skin
-

hunger -
numbers in the skin

, DIABETESSECONDARY TO OTHER CONDITIONI
-
conditions that damage the pancreas including :


>
-
chronic pancreatitis
>
-
carcinoma of the pancreas
>
-

pancreatectomy
> infections
-




>
-


pregnancy (gestational)
>
-
cortisol works against the action of insulin , such as Cushing's syndrome
-

drugs or medications



KIDNEY FAILLIRE
-

glomeruli become scleratic
>
-
necrosis of the papillary tissue
>
-
remal failure




CEREBROVASCULAR DISEASE ,
S



STROKE 3 HYPERTENSION
lipolysis raises fat level in the blood
EYES
-




>
>
-
increased risk of atherosclerosis coronary
artery disease
-

high blood glucose levels damage vessels ,

-


misooangiopathy /small vessel disease) restricts leading to blindness
blood flow ; is associated with serebrovascular -
cataracts form from forstose , sorbital in
disease stroke the lens




COMPLICATIONS OF
DIABETES

> NEUROPATHY
PERIPHERAL VASCULAR DISEASE
-
often affects peripheral nerves
>
-
diminished sensation 3 function
-

secondary to atherosclerosis in the extremities
-
need for amputation


INFECTION
-
decreased immune system

Document information

Uploaded on
November 12, 2025
Number of pages
5
Written in
2024/2025
Type
Class notes
Professor(s)
Ms mcdonald
Contains
All classes
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