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What is MAC? - CORRECT ANSWER-the minimum alveolar concentration needed to achieve surgical anesthesia (immobility) in 50% of patients exposed to noxious stimuli. Think: anesthesia gas dose Blood/Gas Partition Coefficient of Isoflurane - CORRECT ANSWER-1.4 Blood/Gas Partition Coefficient of Sevoflurane - CORRECT ANSWER-0.6 Blood/Gas Partition Coefficient of Desflurane - CORRECT ANSWER-0.42 Blood/Gas Partition Coefficient of N2O - CORRECT ANSWER-0.47 Blood/Gas Partition Coefficient is a measure of _________. - CORRECT ANSWERspeed...how fast you go to sleep and how fast you wake up Put gasses in order of fastest to slowest - CORRECT ANSWER-N2O Desflurane Sevoflurane Isoflurane Oil/Gas Coefficient of Isoflurane - CORRECT ANSWER-99 Oil-Gas Coefficient of Sevoflurane - CORRECT ANSWER-50 Oil/Gas Coefficient of N2O - CORRECT ANSWER-1.4 Oil/Gas Coefficient of Desflurane - CORRECT ANSWER-18.7 Oil/Gas Partition Coefficient is a measure of........ - CORRECT ANSWER-potentcy Put gasses in order of most potent to least potent - CORRECT ANSWER-Isoflurane Sevoflurane Desflurane N2O An INCREASE in cardiac output ________ the onset of all anesthetic gasses. - CORRECT ANSWER-slows A DECREASE in cardiac output ________ the onset of al anesthetic gasses. - CORRECT ANSWER-speedsWhat is the MAC of Isoflurane? - CORRECT ANSWER-1.15 What is the MAC of Sevoflurane? - CORRECT ANSWER-2 What is the MAC of Desflurane? - CORRECT ANSWER-5.8 What is the MAC of N2O? - CORRECT ANSWER-105 Which gases will be effected the most by an increase in cardiac output? - CORRECT ANSWER-the highest blood/gas coefficient gases (slowest) A ventilation/perfusion deficit ________ the delivery of all anesthetic gases. - CORRECT ANSWER-slows Which gases will be effect most by a ventilation/perfusion deficit? - CORRECT ANSWER-the faster inhalation agents (lowest blood/gas partition coefficient) are effected more than the slower inhalation agents (higher blood/gas partition coefficient)

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Nagelhout Pharmacology 1 Exam 2
What is MAC? - CORRECT ANSWER-the minimum alveolar concentration needed to
achieve surgical anesthesia (immobility) in 50% of patients exposed to noxious stimuli.
Think: anesthesia gas dose

Blood/Gas Partition Coefficient of Isoflurane - CORRECT ANSWER-1.4

Blood/Gas Partition Coefficient of Sevoflurane - CORRECT ANSWER-0.6

Blood/Gas Partition Coefficient of Desflurane - CORRECT ANSWER-0.42

Blood/Gas Partition Coefficient of N2O - CORRECT ANSWER-0.47

Blood/Gas Partition Coefficient is a measure of _________. - CORRECT ANSWER-
speed...how fast you go to sleep and how fast you wake up

Put gasses in order of fastest to slowest - CORRECT ANSWER-N2O
Desflurane
Sevoflurane
Isoflurane

Oil/Gas Coefficient of Isoflurane - CORRECT ANSWER-99

Oil-Gas Coefficient of Sevoflurane - CORRECT ANSWER-50

Oil/Gas Coefficient of N2O - CORRECT ANSWER-1.4

Oil/Gas Coefficient of Desflurane - CORRECT ANSWER-18.7

Oil/Gas Partition Coefficient is a measure of........ - CORRECT ANSWER-potentcy

Put gasses in order of most potent to least potent - CORRECT ANSWER-Isoflurane
Sevoflurane
Desflurane
N2O

An INCREASE in cardiac output ________ the onset of all anesthetic gasses. -
CORRECT ANSWER-slows


A DECREASE in cardiac output ________ the onset of al anesthetic gasses. -
CORRECT ANSWER-speeds

, What is the MAC of Isoflurane? - CORRECT ANSWER-1.15

What is the MAC of Sevoflurane? - CORRECT ANSWER-2

What is the MAC of Desflurane? - CORRECT ANSWER-5.8

What is the MAC of N2O? - CORRECT ANSWER-105

Which gases will be effected the most by an increase in cardiac output? - CORRECT
ANSWER-the highest blood/gas coefficient gases (slowest)

A ventilation/perfusion deficit ________ the delivery of all anesthetic gases. -
CORRECT ANSWER-slows

Which gases will be effect most by a ventilation/perfusion deficit? - CORRECT
ANSWER-the faster inhalation agents (lowest blood/gas partition coefficient) are
effected more than the slower inhalation agents (higher blood/gas partition coefficient)

What are the volatile gas anesthetics? - CORRECT ANSWER-Iso, Sevo, Des....these
start in liquid phase and have to be "volatilized" (vaporized) in order to be administered.

What are the non-volatile gas anesthetics? - CORRECT ANSWER-Nitrous
Oxide....already in gas form from the wall

___________ is the only inorganic gas.
All other gases are __________. - CORRECT ANSWER-Nitrous Oxide. Contains no
carbons
Halogenated Ethers

What anesthetics have a GABAMIMETIC mechanism of action? - CORRECT
ANSWER-gases
propofol
benzos
etomidate

Which anesthetics have a NMDA ANTAGONIST mechanism of action? - CORRECT
ANSWER-ketamine

Which anesthetics have a PSA2 ANTAGONIST mechanism of action? - CORRECT
ANSWER-dexmetatomadine

What does a GABA RECEPTOR do? - CORRECT ANSWER-increases chloride
production

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