Update ) Advanced
Pharmacology for the Adult-
Gerontology Primary Care Nurse
Practitioner | Questions with
Answers | 100% Correct | Grade A –
Chamberlain
Question:
What are adverse effects of MAOIs?
Answer:
CNS stimulation, orthostatic hypotension, hypertensive crisis from dietary
tyramine: foods like Avocados, figs, fermented/smoked meats, fish,
milk/cheeses, beer/wine
,Question:
What are signs of serotonin syndrome and when does it begin?
Answer:
2-72 hours of starting treatments/s AMS, incoordination, diaphoresis, tremor,
fever
Question:
Adverse reactions of SSRIs/SNRIs
Answer:
Serotonin syndrome, sexual dysfunction, weight gain, teratogenic
Question:
Which SSRIs can cause QT prolongation in the elderly?
Answer:
Lexapro and Citalopram*cut dose in half
Question:
What increases the risk of Serotonin syndrome when combined with
SSRIs/SNRIs?
Answer:
MAOIs
,Question:
Caution should be taken when combining diuretics with SNRIs because?
Answer:
Hyponatremia
Question:
MAOIs should be withdrawn for how many days prior to starting SNRI/SSRI
Answer:
7 days before/after
Question:
Cardiac monitoring should be done with TCAs because of?
Answer:
Potential for cardiac toxicity (especially with overdose)Monitor ECGs,
orthostatics
Question:
How to treat TCA toxicity?
Answer:
NaHCO3
, Question:
Examples of MAOIs
Answer:
phenelzine (Nardil)Isocarboxazid (Marplan)Tranylcypromine
(Parnate)Selegiline (Emsam)-transdermal MAOI
Question:
Adverse effect of MAOIs
Answer:
hypertensive crisis
Question:
Which medications increase risk of HTN with MAOIs?
Answer:
Sympathometics, TCA, SSRI/SNRI
Question:
Baseline assessment before starting MAOIs? (*think: adverse reactions)
Answer:
Baseline BP