ASAM Essentials of Addiction Medicine Exam
COMPLETE 700 Questions and Detailed
Answers LATEST UPDATE THIS YEAR
QUESTION: Which pharmacologic treatment has consistently demonstrated efficacy in treating
compulsive buying disorders?
A. Opioid antagonists
B. Selective serotonin reuptake inhibitors
C. Glutamate antagonists
D. Dopamine reuptake blockers
E. Currently, no pharmacologic treatments consistently demonstrated efficacy in treating
compulsive buying disorder - ANSWER-E. Currently, no pharmacologic treatments consistently
demonstrated efficacy in treating compulsive buying disorder
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QUESTION: Bioavailability is the fraction of unchanged drug that reaches the systemic
circulation after administered by any route. The bioavailability of drugs administered
intravenously is:
A. 50%
B. 70%
C. 80%
D. 90%
E. 100% - ANSWER-E. 100%
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QUESTION: Drugs with first-order elimination kinetics show an exponential decline of drug
concentrations. The time to reach steady state of drugs with first-order elimination kinetics is
dependent upon:
A. Dose
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B. Frequency of drug administration
C. Half-life
D. First-pass metabolism
E. Enzyme saturation - ANSWER-C. Half-life
Half-life of drugs with first-order elimination kinetics is independent of dose
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QUESTION: Flumazenil can be used to treat benzodiazepine overdose. Flumazenil works at the
benzodiazepine receptors as:
A. An antagonist without intrinsic activity
B. A mixed agonist antagonist
C. An inverse agonist with intrinsic activity
D. A partial agonist
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E. An agonist with intrinsic activity - ANSWER-A. An antagonist without intrinsic activity
Antagonists have no effect when used alone & bind with equal affinity to the active and inactive
receptors and prevent an agonist from inducing a response
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Q; Which of the following neural circuits is never affected by the addiction process?
A. Memory
B. Motivation
C. Reward
D. Introception
E. None of the above - ANSWER-E. None of the above
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